Assessing helical protein interfaces for inhibitor design BN Bullock, AL Jochim, PS Arora Journal of the American Chemical Society 133 (36), 14220-14223, 2011 | 341 | 2011 |
Rational design of topographical helix mimics as potent inhibitors of protein–protein interactions BB Lao, K Drew, DA Guarracino, TF Brewer, DW Heindel, R Bonneau, ... Journal of the American Chemical Society 136 (22), 7877-7888, 2014 | 139 | 2014 |
In vivo modulation of hypoxia-inducible signaling by topographical helix mimetics BB Lao, I Grishagin, H Mesallati, TF Brewer, BZ Olenyuk, PS Arora Proceedings of the National Academy of Sciences 111 (21), 7531-7536, 2014 | 119 | 2014 |
Protein domain mimetics as in vivo modulators of hypoxia-inducible factor signaling S Kushal, BB Lao, LK Henchey, R Dubey, H Mesallati, NJ Traaseth, ... Proceedings of the National Academy of Sciences 110 (39), 15602-15607, 2013 | 111 | 2013 |
Historical changes in the distributions of invasive and endemic marine invertebrates are contrary to global warming predictions: the effects of decadal climate oscillations TJ Hilbish, PM Brannock, KR Jones, AB Smith, BN Bullock, DS Wethey Journal of Biogeography 37 (3), 423-431, 2010 | 96 | 2010 |
Targeting HPV16 E6-p300 interaction reactivates p53 and inhibits the tumorigenicity of HPV-positive head and neck squamous cell carcinoma X Xie, L Piao, BN Bullock, A Smith, T Su, M Zhang, TN Teknos, PS Arora, ... Oncogene 33 (8), 1037-1046, 2014 | 93 | 2014 |
Plucking the high hanging fruit: A systematic approach for targeting protein–protein interactions M Raj, BN Bullock, PS Arora Bioorganic & medicinal chemistry 21 (14), 4051-4057, 2013 | 83 | 2013 |
Adding diverse noncanonical backbones to rosetta: enabling peptidomimetic design K Drew, PD Renfrew, TW Craven, GL Butterfoss, FC Chou, S Lyskov, ... PLoS One 8 (7), e67051, 2013 | 73 | 2013 |
Guest-accelerated molecular rotor BE Dial, RD Rasberry, BN Bullock, MD Smith, PJ Pellechia, S Profeta Jr, ... Organic Letters 13 (2), 244-247, 2011 | 41 | 2011 |
Protein–protein interactions in transcription: A fertile ground for helix mimetics DA Guarracino, BN Bullock, PS Arora Biopolymers 95 (1), 1-7, 2011 | 40 | 2011 |
A small molecule diacid with long-term chiral memory RD Rasberry, X Wu, BN Bullock, MD Smith, KD Shimizu Organic letters 11 (12), 2599-2602, 2009 | 32 | 2009 |
Oligooxopiperazines and methods of making and using them PS Arora, P Tosovska, D Guarracino, B Bullock US Patent 8,791,121, 2014 | 9 | 2014 |
Oligooxopiperazines and methods of making and using them PS Arora, P To, D Guarracino, BB Lao US Patent 9,309,230, 2016 | 7 | 2016 |
Oxopiperazine helix mimetics as inhibitors of the p53-MDM2 interaction PS Arora, BB Lao, D Guarracino, R Bonneau, K Drew US Patent 11,180,481, 2021 | 5 | 2021 |
Oligooxopiperazines and methods of making and using them PS Arora, P To, D Guarracino, BB Lao US Patent 9,624,203, 2017 | 4 | 2017 |
Control of hypoxia-inducible gene expression with oligooxopiperazine nonpeptidic helix mimetics PS Arora, BB Lao US Patent 9,783,526, 2017 | 3 | 2017 |
Oxopiperazine helix mimetics for control of Hypoxia-Inducible gene expression PS Arora, BB Lao, R Bonneau, K Drew US Patent 10,787,424, 2020 | 1 | 2020 |
Oligooxopiperazines as topographical helix mimetics BB Lao, PS Arora Peptidomimetics II, 1-24, 2017 | 1 | 2017 |
Hydrogen bond surrogate (HBS) helices as orthosteric regulator of hypoxia inducible transcription S Kushal, B Bullock, L Henchey, P Arora, B Olenyuk Cancer Research 72 (8_Supplement), 289-289, 2012 | 1 | 2012 |
Oxopiperazine helix mimetics for control of hypoxia-inducible gene expression PS Arora, BB Lao, R Bonneau, K Drew US Patent 11,560,359, 2023 | | 2023 |