Prasanna Venkatraman
Prasanna Venkatraman
Professor, Protein Interaction lab, ACTREC, India
Verified email at - Homepage
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Eukaryotic proteasomes cannot digest polyglutamine sequences and release them during degradation of polyglutamine-containing proteins
P Venkatraman, R Wetzel, M Tanaka, N Nukina, AL Goldberg
Molecular cell 14 (1), 95-104, 2004
Fluorogenic probes for monitoring peptide binding to class II MHC proteins in living cells
P Venkatraman, TT Nguyen, M Sainlos, O Bilsel, S Chitta, B Imperiali, ...
Nature chemical biology 3 (4), 222-228, 2007
Puromycin‐sensitive aminopeptidase is the major peptidase responsible for digesting polyglutamine sequences released by proteasomes during protein degradation
N Bhutani, P Venkatraman, AL Goldberg
The EMBO journal 26 (5), 1385-1396, 2007
The Role of Protein Dynamics in Thymidylate Synthase Catalysis:  Variants of Conserved 2‘-Deoxyuridine 5‘-Monophosphate (dUMP)-Binding Tyr-261,
Z Newby, TT Lee, RJ Morse, Y Liu, L Liu, P Venkatraman, DV Santi, ...
Biochemistry 45 (24), 7415-7428, 2006
A novel pocket in 14-3-3ɛ is required to mediate specific complex formation with cdc25C and to inhibit cell cycle progression upon activation of checkpoint pathways
E Telles, AS Hosing, ST Kundu, P Venkatraman, SN Dalal
Experimental cell research 315 (8), 1448-1457, 2009
Discovery of multiple interacting partners of gankyrin, a proteasomal chaperone and an oncoprotein—Evidence for a common hot spot site at the interface and its functional …
PP Nanaware, MP Ramteke, AK Somavarapu, P Venkatraman
Proteins: Structure, Function, and Bioinformatics 82 (7), 1283-1300, 2014
Cathepsins L and Z are critical in degrading polyglutamine-containing proteins within lysosomes
N Bhutani, R Piccirillo, R Hourez, P Venkatraman, AL Goldberg
Journal of Biological Chemistry 287 (21), 17471-17482, 2012
A novel role for the proteasomal chaperone PSMD 9 and hn RNPA 1 in enhancing IκBα degradation and NF‐κB activation–functional relevance of predicted PDZ domain–motif interaction
I Sahu, N Sangith, M Ramteke, R Gadre, P Venkatraman
The FEBS journal 281 (11), 2688-2709, 2014
Direct ubiquitin independent recognition and degradation of a folded protein by the eukaryotic proteasomes-origin of intrinsic degradation signals
AK Singh Gautam, S Balakrishnan, P Venkatraman
PloS one 7 (4), e34864, 2012
Identification of a novel ATPase activity in 14-3-3 proteins–Evidence from enzyme kinetics, structure guided modeling and mutagenesis studies
MP Ramteke, P Shelke, V Ramamoorthy, AK Somavarapu, AKS Gautam, ...
FEBS letters 588 (1), 71-78, 2014
From prediction to experimental validation: desmoglein 2 is a functionally relevant substrate of matriptase in epithelial cells and their reciprocal relationship is important …
V Wadhawan, YA Kolhe, N Sangith, AKS Gautam, P Venkatraman
Biochemical Journal 447 (1), 61-70, 2012
Structural interrogation of phosphoproteome identified by mass spectrometry reveals allowed and disallowed regions of phosphoconformation
AK Somavarapu, S Balakrishnan, AKS Gautam, DS Palmer, ...
BMC structural biology 14 (1), 1-14, 2014
Discovery of novel interacting partners of PSMD9, a proteasomal chaperone: Role of an Atypical and versatile PDZ-domain motif interaction and identification of putative …
N Sangith, K Srinivasaraghavan, I Sahu, A Desai, S Medipally, ...
FEBS open bio 4, 571-583, 2014
Enhanced proteasomal activity is essential for long term survival and recurrence of innately radiation resistant residual glioblastoma cells
J Rajendra, KK Datta, SBUD Farooqee, R Thorat, K Kumar, N Gardi, ...
Oncotarget 9 (45), 27667, 2018
A sequence and structure based method to predict putative substrates, functions and regulatory networks of endo proteases
P Venkatraman, S Balakrishnan, S Rao, Y Hooda, S Pol
PloS one 4 (5), e5700, 2009
Role of Sug1, a 19S proteasome ATPase, in the transcription of MHC I and the atypical MHC II molecules, HLA-DM and HLA-DO
Y Inostroza-Nieves, P Venkatraman, Z Zavala-Ruiz
Immunology letters 147 (1-2), 67-74, 2012
The polybasic insert, the RBD of the SARS-CoV-2 spike protein, and the feline coronavirus–evolved or yet to evolve
A Budhraja, S Pandey, S Kannan, CS Verma, P Venkatraman
Biochemistry and biophysics reports 25, 100907, 2021
A novel determinant of PSMD9 PDZ binding guides the evolution of the first generation of super binding peptides
M Harish, S Kannan, S Puttagunta, MR Pradhan, CS Verma, ...
Biochemistry 58 (32), 3422-3433, 2019
Specificity in the interaction of natural products with their target proteins-a biochemical and structural insight
P Venkatraman
Mini Reviews in Medicinal Chemistry 10 (6), 540-549, 2010
Phosphorylation promotes binding affinity of Rap-Raf complex by allosteric modulation of switch loop dynamics
P Venkatraman, S Vemparala
Scientific reports 8 (1), 1-15, 2018
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