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Aleksandra M Kubiak
Aleksandra M Kubiak
Post doctoral Researcher, Maastricht University
Verified email at maastrichtuniversity.nl
Title
Cited by
Cited by
Year
Spores of Clostridium engineered for clinical efficacy and safety cause regression and cure of tumors in vivo
JT Heap, J Theys, M Ehsaan, AM Kubiak, L Dubois, K Paesmans, ...
Oncotarget 5 (7), 1761, 2014
862014
The potential of clostridial spores as therapeutic delivery vehicles in tumour therapy
AM Kubiak, NP Minton
Research in microbiology 166 (4), 244-254, 2015
412015
Efficient secretion of murine IL-2 from an attenuated strain of Clostridium sporogenes, a novel delivery vehicle for cancer immunotherapy
AM Kubiak, TS Bailey, LJ Dubois, J Theys, P Lambin
Frontiers in Microbiology 12, 1466, 2021
132021
Use of an optimised enzyme/prodrug combination for Clostridia directed enzyme prodrug therapy induces a significant growth delay in necrotic tumours
AM Mowday, LJ Dubois, AM Kubiak, JVE Chan-Hyams, CP Guise, ...
Cancer Gene Therapy 29 (2), 178-188, 2022
102022
Complete genome sequence of the nonpathogenic soil-dwelling bacterium Clostridium sporogenes strain NCIMB 10696
AM Kubiak, A Poehlein, P Budd, SA Kuehne, K Winzer, J Theys, P Lambin, ...
Genome Announcements 3 (4), 10.1128/genomea. 00942-15, 2015
62015
Heterologous Gene Regulation in Clostridia: Rationally Designed Gene Regulation for Industrial and Medical Applications
Y Zhang, TS Bailey, AM Kubiak, P Lambin, J Theys
ACS Synthetic Biology 11 (11), 3817-3828, 2022
42022
Development of a CRISPR-Cas12a system for efficient genome engineering in clostridia
Y Zhang, AM Kubiak, TS Bailey, L Claessen, P Hittmeyer, L Dubois, ...
Microbiology spectrum 11 (6), e02459-23, 2023
32023
Refined control of CRISPR-Cas9 gene editing in Clostridium sporogenes: the creation of recombinant strains for therapeutic applications
AM Kubiak, L Claessen, Y Zhang, K Khazaie, TS Bailey
Frontiers in immunology 14, 1241632, 2023
12023
Streamlined assembly of cloning and genome editing vectors for genus Clostridium
TS Bailey, P Hittmeyer, Y Zhang, AM Kubiak
Iscience 26 (8), 2023
12023
Clostridia as live biotherapeutics: can modified Clostridium species enhance disease treatments?
AM Kubiak, J de Laak, Y Zhang, TS Bailey, L Claessen, P Hittmeyer, ...
Future Microbiology, 2023
12023
Genetic Engineering of Clostridial Strains for Cancer Therapy
M Zygouropoulou, A Kubiak, AV Patterson, NP Minton
Microbial Infections and Cancer Therapy, 73, 2019
12019
Using modified Clostridium sporogenes as a delivery vehicle for anti-cancer therapeutics
P Budd, A Kubiak, M Collery, C Gustafsson, N Minton, S Kuehne
Annals of Oncology 26, ii20, 2015
12015
The use of Clostridium sporogenes in directed enzyme pro-drug therapy
AM Kubiak
University of Nottingham, 2013
12013
Bugs as Trojan Horses to Target Necrotic Tumors
AM Mowday, NG Lieuwes, R Biemans, R Gehlen, CP Guise, ...
MOLECULAR THERAPY 28 (4), 508-509, 2020
2020
Efficacy of a Novel Enzyme/Prodrug Combination for Clostridia Directed Enzyme Prodrug Therapy
AM Mowday, CP Guise, AM Kubiak, NP Minton, MR Abbattista, P Lambin, ...
Molecular Therapy 25 (5), 131-132, 2017
2017
Clostridium as" Trojan Horse" Vectors for Cancer Treatment
M Zygouropoulou, AM Kubiak, JN Copp, LJ Dubois, AM Mowday, ...
Molecular Therapy 25 (5), 23-23, 2017
2017
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