Shiva Nag Kompella
Shiva Nag Kompella
Verified email at manchester.ac.uk
Title
Cited by
Cited by
Year
Determination of the α-conotoxin Vc1. 1 binding site on the α9α10 nicotinic acetylcholine receptor
R Yu, SN Kompella, DJ Adams, DJ Craik, Q Kaas
Journal of medicinal chemistry 56 (9), 3557-3567, 2013
782013
Dicarba α-Conotoxin Vc1.1 Analogues with Differential Selectivity for Nicotinic Acetylcholine and GABAB Receptors
BJ Van Lierop, SD Robinson, SN Kompella, A Belgi, JR McArthur, A Hung, ...
ACS chemical biology 8 (8), 1815-1821, 2013
602013
Dicarba analogues of α-conotoxin RgIA. Structure, stability, and activity at potential pain targets
S Chhabra, A Belgi, P Bartels, BJ van Lierop, SD Robinson, SN Kompella, ...
Journal of medicinal chemistry 57 (23), 9933-9944, 2014
512014
Isolation and characterization of α-conotoxin LsIA with potent activity at nicotinic acetylcholine receptors
MC Inserra, SN Kompella, I Vetter, A Brust, NL Daly, H Cuny, DJ Craik, ...
Biochemical pharmacology 86 (6), 791-799, 2013
442013
RegIIA: an α4/7-conotoxin from the venom of Conus regius that potently blocks α3β4 nAChRs
A Franco, SN Kompella, KB Akondi, C Melaun, NL Daly, CW Luetje, ...
Biochemical pharmacology 83 (3), 419-426, 2012
442012
Alanine scan of α-conotoxin RegIIA reveals a selective α3β4 nicotinic acetylcholine receptor antagonist
SN Kompella, A Hung, RJ Clark, F Marí, DJ Adams
Journal of Biological Chemistry 290 (2), 1039-1048, 2015
312015
Embryonic toxin expression in the cone snail Conus victoriae: primed to kill or divergent function?
H Safavi-Hemami, WA Siero, Z Kuang, NA Williamson, JA Karas, LR Page, ...
Journal of Biological Chemistry 286 (25), 22546-22557, 2011
292011
Conotoxin αD-GeXXA utilizes a novel strategy to antagonize nicotinic acetylcholine receptors
S Xu, T Zhang, SN Kompella, M Yan, A Lu, Y Wang, X Shao, C Chi, ...
Scientific reports 5 (1), 1-8, 2015
252015
Polyaromatic hydrocarbons in pollution: a heart‐breaking matter
CR Marris, SN Kompella, MR Miller, JP Incardona, F Brette, JC Hancox, ...
The Journal of physiology 598 (2), 227-247, 2020
242020
Molecular basis for differential sensitivity of α-conotoxin RegIIA at rat and human neuronal nicotinic acetylcholine receptors
SN Kompella, H Cuny, A Hung, DJ Adams
Molecular pharmacology 88 (6), 993-1001, 2015
172015
α‐Conotoxins active at α3‐containing nicotinic acetylcholine receptors and their molecular determinants for selective inhibition
H Cuny, R Yu, HS Tae, SN Kompella, DJ Adams
British journal of pharmacology 175 (11), 1855-1868, 2018
132018
Key structural determinants in the agonist binding loops of human β2 and β4 nicotinic acetylcholine receptor subunits contribute to α3β4 subtype selectivity of α-conotoxins
H Cuny, SN Kompella, HS Tae, R Yu, DJ Adams
Journal of Biological Chemistry 291 (45), 23779-23792, 2016
132016
Understanding the cardiac toxicity of the anthropogenic pollutant phenanthrene on the freshwater indicator species, the brown trout (Salmo trutta): From whole heart to …
MO Ainerua, J Tinwell, SN Kompella, E Sørhus, KN White, ...
Chemosphere 239, 124608, 2020
112020
Phenanthrene impacts zebrafish cardiomyocyte excitability by inhibiting IKr and shortening action potential duration
SN Kompella, F Brette, JC Hancox, HA Shiels
Journal of General Physiology 153 (2), 2021
22021
Dicarba modification of α-conotoxin RgIA conferring selectivity towards α9α10 nicotinic acetylcholine receptors
SN Kompella, BJ van Lierop, SD Robinson, A Belgi, B Callaghan, A Hung, ...
Biochemical Pharmacology 8 (86), 1230, 2013
22013
Phenanthrene alters the electrical activity of atrial and ventricular myocytes of a polar fish, the Navaga cod
DV Abramochkin, SN Kompella, HA Shiels
Aquatic Toxicology 235, 105823, 2021
2021
Dissecting the nachr-inhibiting D-conotoxin GeXXA
S Xu, L Yang, SN Kompella, HS Tae, T Zhang, A Lv, Y Wang, X Shao, ...
Toxicon 158, S26, 2019
2019
-Conotoxins active at 3-containing nicotinic acetylcholine receptors and their molecular determinants for selective inhibition
H Cuny, R Yu, HS Tae, SN Kompella, DJ Adams
2017
Key Structural Determinants in the Agonist Binding Loops of Human 2 and 4 Nicotinic Acetylcholine Receptor Subunits Contribute to 3 4 Subtype Selectivity of-Conotoxins
H Cuny, SN Kompella, HS Tae, R Yu, DJ Adams
2016
α-Conotoxin Regiia Targeting Nicotinic Acetylcholine Receptors: Mutagenesis Studies Improving Selectivity and Potency
SN Kompella, A Hung, RJ Clark, DJ Adams
Biophysical Journal 104 (2), 634a, 2013
2013
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Articles 1–20