Identification of novel specific and general inhibitors of the three major human ATP-binding cassette transporters P-gp, BCRP and MRP2 among registered drugs P Matsson, JM Pedersen, U Norinder, CAS Bergström, P Artursson Pharmaceutical research 26, 1816-1831, 2009 | 356 | 2009 |
Structural requirements for drug inhibition of the liver specific human organic cation transport protein 1 G Ahlin, J Karlsson, JM Pedersen, L Gustavsson, R Larsson, P Matsson, ... Journal of medicinal chemistry 51 (19), 5932-5942, 2008 | 218 | 2008 |
Early identification of clinically relevant drug interactions with the human bile salt export pump (BSEP/ABCB11) JM Pedersen, P Matsson, CAS Bergström, J Hoogstraate, A Norén, ... toxicological sciences 136 (2), 328-343, 2013 | 174 | 2013 |
Prediction and identification of drug interactions with the human ATP-binding cassette transporter multidrug-resistance associated protein 2 (MRP2; ABCC2) JM Pedersen, P Matsson, CAS Bergström, U Norinder, J Hoogstraate, ... Journal of medicinal chemistry 51 (11), 3275-3287, 2008 | 149 | 2008 |
Can bile salt export pump inhibition testing in drug discovery and development reduce liver injury risk? An international transporter consortium perspective JG Kenna, KS Taskar, C Battista, DL Bourdet, KLR Brouwer, KR Brouwer, ... Clinical Pharmacology & Therapeutics 104 (5), 916-932, 2018 | 88 | 2018 |
Substrate and method dependent inhibition of three ABC-transporters (MDR1, BCRP, and MRP2) JM Pedersen, EK Khan, CAS Bergström, J Palm, J Hoogstraate, ... European journal of pharmaceutical sciences 103, 70-76, 2017 | 31 | 2017 |
Fluid dynamic modeling to support the development of flow-based hepatocyte culture systems for metabolism studies JM Pedersen, YS Shim, V Hans, MB Phillips, JM Macdonald, G Walker, ... Frontiers in Bioengineering and Biotechnology 4, 72, 2016 | 23 | 2016 |
Xenobiotic metabolism in alginate-encapsulated primary human hepatocytes over long timeframes MB Phillips, P Balbuena-Venancio, JR Enders, RL Norini, YS Shim, ... Applied In Vitro Toxicology 4 (3), 238-247, 2018 | 8 | 2018 |
Hepatocyte size fractionation allows dissection of human liver zonation M Ölander, C Wegler, I Flörkemeier, A Treyer, N Handin, JM Pedersen, ... Journal of Cellular Physiology 236 (8), 5885-5894, 2021 | 7 | 2021 |
Bioethical implications of globalization: an international consortium project of the European Commission TE Novotny, E Mordini, R Chadwick, JM Pedersen, F Fabbri, R Lie, ... PloS Medicine 3 (2), e43, 2006 | 6 | 2006 |
ATP-Binding-Cassette transporters in biliary efflux and drug-induced liver injury JM Pedersen Acta Universitatis Upsaliensis, 2013 | 4 | 2013 |
Liver bioreactor as an in vitro metabolism system for quantitative in vitro to in vivo extrapolation M Yoon, J Pedersen, E LeCluyse, M Andersen, H Clewell Toxicology Letters, S13, 2014 | 1 | 2014 |
IDENTIFICATION AND PREDICTION OF INHIBITORS OF THE THREE MAJOR HUMAN ATP-BINDING CASSETTE TRANSPORTERS P GP, MRP2 AND BCRP P Matsson, J Pedersen, U Norinder, C Bergstrom, P Artursson Drug Metabolism Reviews 40, 161-162, 2008 | 1 | 2008 |