Dr. Thirumal Kumar D, M.Sc (Biotech), Ph.D., FLS (London), MRSB (UK)
Dr. Thirumal Kumar D, M.Sc (Biotech), Ph.D., FLS (London), MRSB (UK)
Saveetha School of Engineering, Saveetha Institute of Medical and Technical Sciences, Chennai, India
Verified email at vit.ac.in
Title
Cited by
Cited by
Year
Influence of V54M mutation in giant muscle protein titin: a computational screening and molecular dynamics approach
DT Kumar, C Doss, G Priya, P Sneha, IA Tayubi, R Siva, C Chakraborty, ...
Journal of Biomolecular Structure & Dynamics 35 (5), 917-928, 2017
522017
Structural Analysis of G1691S Variant in the Human Filamin B Gene Responsible for Larsen Syndrome: A Comparative Computational Approach.
D KT, H Tanwar, C GPD, H Zayed
Journal of cellular biochemistry 118 (7), 1900-1910, 2017
372017
Investigating the inhibitory effect of Wortmannin in the hotspot mutation at codon 1047 of PIK3CA kinase domain: a molecular docking and molecular dynamics approach
DT Kumar, CGP Doss
Advances in protein chemistry and structural biology 102, 267-297, 2016
352016
The Rise and Impact of COVID-19 in India
SU Kumar, DT Kumar, BP Christopher, C Doss
Frontiers in Medicine 7, 250, 2020
322020
Functionality study of santalin as tyrosinase inhibitor: A potential depigmentation agent
H Hridya, A Amrita, S Mohan, M Gopalakrishnan, TK Dakshinamurthy, ...
International journal of biological macromolecules 86, 383-389, 2016
322016
Deciphering the impact of somatic mutations in exon 20 and exon 9 of PIK3CA gene in breast tumors among Indian women through molecular dynamics approach
N Sudhakar, C George Priya Doss, D Thirumal Kumar, C Chakraborty, ...
Journal of Biomolecular Structure and Dynamics 34 (1), 29-41, 2016
322016
Role of E542 and E545 missense mutations of PIK3CA in breast cancer: a comparative computational approach
D Thirumal Kumar, C George Priya Doss
Journal of Biomolecular Structure and Dynamics 35 (12), 2745-2757, 2017
312017
Unraveling the inhibition mechanism of cyanidin-3-sophoroside on polyphenol oxidase and its effect on enzymatic browning of apples
H Hemachandran, A Anantharaman, S Mohan, G Mohan, DT Kumar, ...
Food chemistry 227, 102-110, 2017
312017
Determining the role of missense mutations in the POU domain of HNF1A that reduce the DNA-binding affinity: A computational approach
H Zayed
PLoS One 12 (4), e0174953, 2017
292017
Computational approach to unravel the impact of missense mutations of proteins (D2HGDH and IDH2) causing D-2-hydroxyglutaric aciduria 2
DT Kumar, LJ Emerald, CGP Doss, P Sneha, R Siva, WCE Jebaraj, ...
Metabolic brain disease 33 (5), 1699-1710, 2018
282018
Computational approaches and resources in single amino acid substitutions analysis toward clinical research
CGP Doss, C Chakraborty, V Narayan, DT Kumar
Advances in protein chemistry and structural biology 94, 365-423, 2014
262014
Computational modelling approaches as a potential platform to understand the molecular genetics association between Parkinson’s and Gaucher diseases
DT Kumar, HG Eldous, ZA Mahgoub, CGP Doss, H Zayed
Metabolic Brain Disease 33 (6), 1835-1847, 2018
252018
Genotype–phenotype correlation in patients with isovaleric acidaemia: comparative structural modelling and computational analysis of novel variants
OK Zaki, G Priya Doss C, SA Ali, GG Murad, SA Elashi, MSA Ebnou, ...
Human Molecular Genetics 26 (16), 3105-3115, 2017
252017
Binding and molecular dynamic studies of sesquiterpenes (2R-acetoxymethyl-1, 3, 3-trimethyl-4t-(3-methyl-2-buten-1-yl)-1t-cyclohexanol) derived from marine Streptomyces sp …
SJ Naine, CS Devi, V Mohanasrinivasan, CGP Doss, DT Kumar
Applied microbiology and biotechnology 100 (6), 2869-2882, 2016
252016
Mechanism of artemisinin resistance for malaria PfATP6 L263 mutations and discovering potential antimalarials: an integrated computational approach
N Nagasundaram, C Chakraborty, V Karthick, V Balaji, R Siva, A Lu, Z Ge, ...
Scientific reports 6 (1), 1-12, 2016
232016
Structural analysis of missense mutations in galactokinase 1 (GALK1) leading to galactosemia type-2.
EA Ebrahimi, SA Ghazala, D TK, PD CG, H Zayed
Journal of cellular biochemistry 119 (9), 7585-7598, 2018
222018
Induction of apoptosis by apocarotenoids in B16 melanoma cells through ROS-mediated mitochondrial-dependent pathway
A Anantharaman, H Hemachandran, S Mohan, DM Ayyathan, R Siva
Journal of Functional Foods 20, 346-357, 2016
212016
Exploring the interaction between iron oxide nanoparticles (IONPs) and human serum albumin (HSA): spectroscopic and docking studies
G Sekar, M Haldar, DT Kumar, CGP Doss, A Mukherjee, ...
Journal of Molecular Liquids 241, 793-800, 2017
182017
DNA Repair Gene (XRCC1) Polymorphism (Arg399Gln) Associated with Schizophrenia in South Indian Population: A Genotypic and Molecular Dynamics Study
SP Sujitha, DT Kumar, CGP Doss, K Aavula, R Ramesh, S Lakshmanan, ...
PloS one 11 (1), e0147348, 2016
172016
A computational method to characterize the missense mutations in the catalytic domain of GAA protein causing Pompe disease
D Thirumal Kumar, M Umer Niazullah, S Tasneem, E Judith, B Susmita, ...
Journal of Cellular Biochemistry 120 (3), 3491-3505, 2019
132019
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