| Selective BCL-2 inhibition by ABT-199 causes on-target cell death in acute myeloid leukemia R Pan, LJ Hogdal, JM Benito, D Bucci, L Han, G Borthakur, J Cortes, ... Cancer discovery 4 (3), 362-375, 2014 | 722 | 2014 |
| Synthetic lethality of combined Bcl-2 inhibition and p53 activation in AML: mechanisms and superior antileukemic efficacy R Pan, V Ruvolo, H Mu, JD Leverson, G Nichols, JC Reed, M Konopleva, ... Cancer cell 32 (6), 748-760. e6, 2017 | 248 | 2017 |
| Inhibition of Mcl-1 with the pan–Bcl-2 family inhibitor (–) BI97D6 overcomes ABT-737 resistance in acute myeloid leukemia R Pan, VR Ruvolo, J Wei, M Konopleva, JC Reed, M Pellecchia, ... Blood, The Journal of the American Society of Hematology 126 (3), 363-372, 2015 | 152 | 2015 |
| Augmenting NK cell-based immunotherapy by targeting mitochondrial apoptosis R Pan, J Ryan, D Pan, KW Wucherpfennig, A Letai Cell 185 (9), 1521-1538. e18, 2022 | 80 | 2022 |
| Disruption of Wnt/β-catenin exerts antileukemia activity and synergizes with FLT3 inhibition in FLT3-mutant acute myeloid leukemia X Jiang, PY Mak, H Mu, W Tao, DH Mak, S Kornblau, Q Zhang, P Ruvolo, ... Clinical Cancer Research 24 (10), 2417-2429, 2018 | 79 | 2018 |
| Activation of RAS/MAPK pathway confers MCL-1 mediated acquired resistance to BCL-2 inhibitor venetoclax in acute myeloid leukemia Q Zhang, B Riley-Gillis, L Han, Y Jia, A Lodi, H Zhang, S Ganesan, R Pan, ... Signal transduction and targeted therapy 7 (1), 51, 2022 | 71 | 2022 |
| Sequential deletion of Pichia pastoris genes by a self-excisable cassette R Pan, J Zhang, WL Shen, ZQ Tao, SP Li, X Yan Fems yeast research 11 (3), 292-298, 2011 | 63 | 2011 |
| Selective BCL-2 inhibition by ABT-199 causes on-target cell death in acute myeloid leukemia. Cancer Discov. 2014; 4: 362–375. doi: 10.1158/2159-8290 R Pan, LJ Hogdal, JM Benito, D Bucci, L Han, G Borthakur, J Cortes, ... CD-13-0609.[Europe PMC free article][Abstract][CrossRef][Google Scholar], 0 | 62 | |
| Antileukemia efficacy and mechanisms of action of SL-101, a novel anti-CD123 antibody conjugate, in acute myeloid leukemia L Han, JL Jorgensen, C Brooks, C Shi, Q Zhang, GM Nogueras González, ... Clinical Cancer Research 23 (13), 3385-3395, 2017 | 45 | 2017 |
| The protein phosphatase 2A regulatory subunit B55α is a modulator of signaling and microRNA expression in acute myeloid leukemia cells PP Ruvolo, VR Ruvolo, R Jacamo, JK Burks, Z Zeng, SR Duvvuri, L Zhou, ... Biochimica et Biophysica Acta (BBA)-Molecular Cell Research 1843 (9), 1969-1977, 2014 | 42 | 2014 |
| Biguanides sensitize leukemia cells to ABT-737-induced apoptosis by inhibiting mitochondrial electron transport J Velez, R Pan, JTC Lee, L Enciso, M Suarez, JE Duque, D Jaramillo, ... Oncotarget 7 (32), 51435, 2016 | 35 | 2016 |
| Demethylation and up-regulation of an oncogene after hypomethylating therapy YC Liu, J Kwon, E Fabiani, Z Xiao, YV Liu, MY Follo, J Liu, H Huang, ... New England Journal of Medicine 386 (21), 1998-2010, 2022 | 25 | 2022 |
| Selective BCL-2 inhibition by ABT-199 causes on-target cell death in acute myeloid leukemia. Cancer Discov. 2014; 4 (3): 362–375. doi: 10.1158/2159-8290 R Pan, LJ Hogdal, JM Benito, D Bucci, L Han, G Borthakur, J Cortes, ... CD-13-0609.[Europe PMC free article][Abstract][CrossRef][Google Scholar], 0 | 16 | |
| Selective BCL-2 inhibition by ABT-199 causes on-target cell. death in acute myeloid leukemia. Cancer Discov. 2014; 4 (3): 362-75. doi: 10.1158/2159-8290 R Pan, LJ Hogdal, JM Benito, D Bucci, L Han, G Borthakur CD-13-0609, 0 | 13 | |
| Selective BCL-2 inhibition by ABT-199 causes on-target cell death in acute myeloid leukemia. Cancer Discov.(2014) 4: 362–75. doi: 10.1158/2159-8290 R Pan, LJ Hogdal, JM Benito, D Bucci, L Han, G Borthakur, J Cortes, ... CD-13-0609, 0 | 11 | |
| Selective BCL-2 inhibition by ABT-199 causes on-target cell death in acute myeloid leukemia. Cancer Discov. 2014; 4 (3): 362–75 R Pan, LJ Hogdal, JM Benito, D Bucci, L Han, G Borthakur | 11 | |
| Activation of p53 by novel MDM2 antagonist RG7388 overcomes AML inherent and acquired resistance to Bcl-2 inhibitor ABT-199 (GDC-0199) R Pan, K Kojima, Z Zheng, VR Ruvolo, G Nichols, JD Leverson, M Dangl, ... Blood 124 (21), 2162, 2014 | 10 | 2014 |
| Mechanisms of acquired resistance to venetoclax in preclinical AML models Q Zhang, R Pan, L Han, C Shi, SE Kurtz, H Mu, H Ma, M Andreeff, ... Blood 126 (23), 328, 2015 | 9 | 2015 |
| BCL-2 inhibition by ABT-199 (venetoclax/GDC-0199) and p53 activation by RG7388 (idasanutlin) reciprocally overcome leukemia apoptosis resistance to either strategy alone … R Pan, V Ruvolo, H Mu, Z Zheng, J Leverson, K Kojima, M Konopleva, ... Blood 126 (23), 673, 2015 | 9 | 2015 |
| Proteomic, gene expression, and Micro-RNA analysis of bone marrow mesenchymal stromal cells in acute myeloid leukemia identifies Pro-Inflammatory, Pro-Survival signatures in … M Andreeff, R Wang, RE Davis, R Jacamo, PP Ruvolo, T McQueen, ... Blood, The Journal of the American Society of Hematology 122 (21), 3685-3685, 2013 | 9 | 2013 |
Lina HanMD Anderson Cancer CenterVerified email at mdanderson.org
