| Nrf2 suppresses macrophage inflammatory response by blocking proinflammatory cytokine transcription EH Kobayashi, T Suzuki, R Funayama, T Nagashima, M Hayashi, ... Nature communications 7 (1), 1-14, 2016 | 1395 | 2016 |
| Molecular basis of the Keap1–Nrf2 system T Suzuki, M Yamamoto Free Radical Biology and Medicine 88, 93-100, 2015 | 865 | 2015 |
| Loss of Keap1 function activates Nrf2 and provides advantages for lung cancer cell growth T Ohta, K Iijima, M Miyamoto, I Nakahara, H Tanaka, M Ohtsuji, T Suzuki, ... Cancer research 68 (5), 1303-1309, 2008 | 713 | 2008 |
| Toward clinical application of the Keap1–Nrf2 pathway T Suzuki, H Motohashi, M Yamamoto Trends in pharmacological sciences 34 (6), 340-346, 2013 | 702 | 2013 |
| Physiological significance of reactive cysteine residues of Keap1 in determining Nrf2 activity T Yamamoto, T Suzuki, A Kobayashi, J Wakabayashi, J Maher, ... Molecular and cellular biology 28 (8), 2758-2770, 2008 | 556 | 2008 |
| Identification of the interactive interface and phylogenic conservation of the Nrf2‐Keap1 system M Kobayashi, K Itoh, T Suzuki, H Osanai, K Nishikawa, Y Katoh, Y Takagi, ... Genes to Cells 7 (8), 807-820, 2002 | 409 | 2002 |
| Stress-sensing mechanisms and the physiological roles of the Keap1–Nrf2 system during cellular stress T Suzuki, M Yamamoto Journal of Biological Chemistry 292 (41), 16817-16824, 2017 | 366 | 2017 |
| p62/Sqstm1 promotes malignancy of HCV-positive hepatocellular carcinoma through Nrf2-dependent metabolic reprogramming T Saito, Y Ichimura, K Taguchi, T Suzuki, T Mizushima, K Takagi, Y Hirose, ... Nature communications 7 (1), 12030, 2016 | 298 | 2016 |
| Validation of the multiple sensor mechanism of the Keap1-Nrf2 system K Takaya, T Suzuki, H Motohashi, K Onodera, S Satomi, TW Kensler, ... Free Radical Biology and Medicine 53 (4), 817-827, 2012 | 287 | 2012 |
| The aryl hydrocarbon receptor AhR links atopic dermatitis and air pollution via induction of the neurotrophic factor artemin T Hidaka, E Ogawa, EH Kobayashi, T Suzuki, R Funayama, T Nagashima, ... Nature immunology 18 (1), 64-73, 2017 | 258 | 2017 |
| Genetic analysis of cytoprotective functions supported by graded expression of Keap1 K Taguchi, JM Maher, T Suzuki, Y Kawatani, H Motohashi, M Yamamoto Molecular and cellular biology 30 (12), 3016-3026, 2010 | 237 | 2010 |
| Characterizations of three major cysteine sensors of Keap1 in stress response R Saito, T Suzuki, K Hiramoto, S Asami, E Naganuma, H Suda, T Iso, ... Molecular and cellular biology 36 (2), 271-284, 2016 | 235 | 2016 |
| Nrf2-deficiency creates a responsive microenvironment for metastasis to the lung H Satoh, T Moriguchi, K Taguchi, J Takai, JM Maher, T Suzuki, ... Carcinogenesis 31 (10), 1833-1843, 2010 | 224 | 2010 |
| Molecular mechanism of cellular oxidative stress sensing by Keap1 T Suzuki, A Muramatsu, R Saito, T Iso, T Shibata, K Kuwata, S Kawaguchi, ... Cell reports 28 (3), 746-758. e4, 2019 | 197 | 2019 |
| The homeobox protein Six3 interacts with the Groucho corepressor and acts as a transcriptional repressor in eye and forebrain formation M Kobayashi, K Nishikawa, T Suzuki, M Yamamoto Developmental biology 232 (2), 315-326, 2001 | 193 | 2001 |
| Mitochondrial SKN-1/Nrf mediates a conserved starvation response J Paek, JY Lo, SD Narasimhan, TN Nguyen, K Glover-Cutter, ... Cell metabolism 16 (4), 526-537, 2012 | 183 | 2012 |
| Transcription factor Nrf2 hyperactivation in early-phase renal ischemia-reperfusion injury prevents tubular damage progression M Nezu, T Souma, L Yu, T Suzuki, D Saigusa, S Ito, N Suzuki, ... Kidney international 91 (2), 387-401, 2017 | 177 | 2017 |
| Environmental pollutants and the immune response T Suzuki, T Hidaka, Y Kumagai, M Yamamoto Nature Immunology 21 (12), 1486-1495, 2020 | 176 | 2020 |
| Global downstream pathway analysis reveals a dependence of oncogenic NF-E2–related factor 2 mutation on the mTOR growth signaling pathway T Shibata, S Saito, A Kokubu, T Suzuki, M Yamamoto, S Hirohashi Cancer research 70 (22), 9095-9105, 2010 | 139 | 2010 |
| Regulatory nexus of synthesis and degradation deciphers cellular Nrf2 expression levels T Suzuki, T Shibata, K Takaya, K Shiraishi, T Kohno, H Kunitoh, K Tsuta, ... Molecular and cellular biology, 2013 | 137 | 2013 |
Motohashi HozumiInstitute of Development, Aging and Cancer, Tohoku UniversityVerified email at tohoku.ac.jp
