| A Theory of Self-Nonself Discrimination: Paralysis and induction involve the recognition of one and two determinants on an antigen, respectively. P Bretscher, M Cohn Science 169 (3950), 1042-1049, 1970 | 2405 | 1970 |
| Establishment of stable, cell-mediated immunity that makes" susceptible" mice resistant to Leishmania major PA Bretscher, G Wei, JN Menon, H Bielefeldt-Ohmann Science 257 (5069), 539-542, 1992 | 664 | 1992 |
| A two-step, two-signal model for the primary activation of precursor helper T cells PA Bretscher Proceedings of the National Academy of Sciences 96 (1), 185-190, 1999 | 557 | 1999 |
| The two-signal model of lymphocyte activation twenty-one years later P Bretscher Immunology Today 13 (2), 74-76, 1992 | 332 | 1992 |
| A strategy for prophylactic vaccination against HIV J Salk, PA Bretscher, PL Salk, M Clerici, GM Shearer Science 260 (5112), 1270-1272, 1993 | 249 | 1993 |
| Mycobacterial dose defines the Th1/Th2 nature of the immune response independently of whether immunization is administered by the intravenous, subcutaneous, or intradermal route CA Power, G Wei, PA Bretscher Infection and immunity 66 (12), 5743-5750, 1998 | 243 | 1998 |
| Immune elimination of Leishmania major in mice: implications for immune memory, vaccination, and reactivation disease JE Uzonna, G Wei, D Yurkowski, P Bretscher The Journal of Immunology 167 (12), 6967-6974, 2001 | 227 | 2001 |
| Minimal model for the mechanism of antibody induction and paralysis by antigen PA Bretscher, M Cohn Nature 220 (5166), 444-448, 1968 | 220 | 1968 |
| Regulation of the immune response. I. Suppression of delayed‐type hypersensitivity by T cells from mice expressing humoral immunity IA Ramshaw, PA Bretscher, CR Parish European Journal of Immunology 6 (10), 674-679, 1976 | 173 | 1976 |
| Parasite dose determines the Th1/Th2 nature of the response to Leishmania major independently of infection route and strain of host or parasite JN Menon, PA Bretscher European journal of immunology 28 (12), 4020-4028, 1998 | 139 | 1998 |
| On the control between cell-mediated, IgM and IgG immunity PA Bretscher Cellular immunology 13 (2), 171-195, 1974 | 139 | 1974 |
| A strategy to improve the efficacy of vaccination against tuberculosis and leprosy PA Bretscher Immunology Today 13 (9), 342-345, 1992 | 136 | 1992 |
| On the mechanism determining the TH1/TH2 phenotype of an immune response, and its pertinence to strategies for the prevention, and treatment, of certain infectious diseases PA Bretscher Scandinavian journal of immunology 79 (6), 361-376, 2014 | 117 | 2014 |
| A valid ELISPOT assay for enumeration of ex vivo, antigen-specific, IFNγ-producing T cells CA Power, CL Grand, N Ismail, NC Peters, DP Yurkowski, PA Bretscher Journal of immunological methods 227 (1-2), 99-107, 1999 | 109 | 1999 |
| The control of humoral and associative antibody synthesis P Bretscher Immunological Reviews 11 (1), 217-267, 1972 | 105 | 1972 |
| Phospholipid oxidation generates potent anti‐inflammatory lipid mediators that mimic structurally related pro‐resolving eicosanoids by activating Nrf2 P Bretscher, J Egger, A Shamshiev, M Trötzmüller, H Köfeler, EM Carreira, ... EMBO molecular medicine 7 (5), 593-607, 2015 | 104 | 2015 |
| Discrimination of suppressor T cells of humoral and cell-mediated immunity by anti-Ly and anti-Ia sera IA Ramshaw, IFC McKenzie, PA Bretscher, CR Parish Cellular immunology 31 (2), 364-369, 1977 | 101 | 1977 |
| Characterization of the immunological memory state generated in mice susceptible to Leishmania major following exposure to low doses of L. major and resulting … JN Menon, PA Bretscher European Journal of Immunology 26 (1), 243-249, 1996 | 87 | 1996 |
| T cells cooperating in the induction of delayed-type hypersensitivity act via the linked recognition of antigenic determinants. MJ Tucker, PA Bretscher The Journal of experimental medicine 155 (4), 1037-1049, 1982 | 87 | 1982 |
| Regulation of the immune response II. Repressor T cells in cyclophosphamide‐induced tolerant mice IA Ramshav, PA Bretscher, CR Parish European Journal of Immunology 7 (3), 180-185, 1977 | 84 | 1977 |
Linda M. PilarskiProfessor, Dept Oncology, University of Alberta and Cross Cancer InstituteVerified email at ualberta.ca
