Christine M. Eischen
Christine M. Eischen
Professor of Pathology, Microbiology and Immunology, Cancer Biology, Vanderbilt University
Verified email at - Homepage
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Cited by
Myc signaling via the ARF tumor suppressor regulates p53-dependent apoptosis and immortalization
F Zindy, CM Eischen, DH Randle, T Kamijo, JL Cleveland, CJ Sherr, ...
Genes & development 12 (15), 2424-2433, 1998
Disruption of the ARF–Mdm2–p53 tumor suppressor pathway in Myc-induced lymphomagenesis
CM Eischen, JD Weber, MF Roussel, CJ Sherr, JL Cleveland
Genes & development 13 (20), 2658-2669, 1999
Comparison of apoptosis in wild-type and Fas-resistant cells: chemotherapy-induced apoptosis is not dependent on Fas/Fas ligand interactions
CM Eischen, TJ Kottke, LM Martins, GS Basi, JS Tung, WC Earnshaw, ...
Blood 90 (3), 935-943, 1997
Interaction with WDR5 Promotes Target Gene Recognition and Tumorigenesis by MYC
LR Thomas, Q Wang, BC Grieb, J Phan, AM Foshage, Q Sun, ...
Molecular cell, 2015
Apoptosis triggered by Myc-induced suppression of Bcl-XL or Bcl-2 is bypassed during lymphomagenesis
CM Eischen, D Woo, MF Roussel, JL Cleveland
Molecular and cellular biology 21 (15), 5063-5070, 2001
Tyrosine kinase activation provides an early and requisite signal for Fas-induced apoptosis.
CM Eischen, CJ Dick, PJ Leibson
The Journal of immunology 153 (5), 1947-1954, 1994
Bax loss impairs Myc-induced apoptosis and circumvents the selection of p53 mutations during Myc-mediated lymphomagenesis
CM Eischen, MF Roussel, SJ Korsmeyer, JL Cleveland
Molecular and cellular biology 21 (22), 7653-7662, 2001
Loss of miRNA biogenesis induces p19Arf-p53 signaling and senescence in primary cells
R Mudhasani, Z Zhu, G Hutvagner, CM Eischen, S Lyle, LL Hall, ...
The Journal of cell biology 181 (7), 1055-1063, 2008
Bcl-2 is an apoptotic target suppressed by both c-Myc and E2F-1.
CM Eischen, G Packham, J Nip, BE Fee, SW Hiebert, GP Zambetti, ...
Oncogene 20 (48), 6983-6993, 2001
Apoptosis-inducing factor mediates microglial and neuronal apoptosis caused by pneumococcus
JS Braun, R Novak, PJ Murray, CM Eischen, SA Susin, G Kroemer, ...
Journal of Infectious Diseases 184 (10), 1300-1309, 2001
Fc receptor-induced expression of Fas ligand on activated NK cells facilitates cell-mediated cytotoxicity and subsequent autocrine NK cell apoptosis.
CM Eischen, JD Schilling, DH Lynch, PH Krammer, PJ Leibson
The Journal of Immunology 156 (8), 2693-2699, 1996
Mdm2 haplo‐insufficiency profoundly inhibits Myc‐induced lymphomagenesis
JR Alt, TC Greiner, JL Cleveland, CM Eischen
The EMBO journal 22 (6), 1442-1450, 2003
Mdm2 binds to Nbs1 at sites of DNA damage and regulates double strand break repair
JR Alt, A Bouska, MR Fernandez, RL Cerny, H Xiao, CM Eischen
Journal of Biological Chemistry 280 (19), 18771-18781, 2005
Selective regulation of Bcl-XL by a Jak kinase-dependent pathway is bypassed in murine hematopoietic malignancies
G Packham, EL White, CM Eischen, H Yang, E Parganas, JN Ihle, ...
Genes & development 12 (16), 2475-2487, 1998
Glycolytic rate and lymphomagenesis depend on PARP14, an ADP ribosyltransferase of the B aggressive lymphoma (BAL) family
SH Cho, AK Ahn, P Bhargava, CH Lee, CM Eischen, O McGuinness, ...
Proceedings of the National Academy of Sciences 108 (38), 15972-15977, 2011
Mdm2 promotes genetic instability and transformation independent of p53
A Bouska, T Lushnikova, S Plaza, CM Eischen
Molecular and cellular biology 28 (15), 4862-4874, 2008
PARP-14, a member of the B aggressive lymphoma family, transduces survival signals in primary B cells
SH Cho, S Goenka, T Henttinen, P Gudapati, A Reinikainen, CM Eischen, ...
Blood 113 (11), 2416-2425, 2009
The RING domain of Mdm2 can inhibit cell proliferation
J Dang, ML Kuo, CM Eischen, L Stepanova, CJ Sherr, MF Roussel
Cancer research 62 (4), 1222-1230, 2002
Inhibition of histone deacetylase 3 causes replication stress in cutaneous T cell lymphoma
CE Wells, S Bhaskara, KR Stengel, Y Zhao, B Sirbu, B Chagot, D Cortez, ...
PloS one 8 (7), e68915, 2013
miR-223 Regulates cell growth and targets proto-oncogenes in mycosis fungoides/cutaneous T-cell lymphoma
LY McGirt, CM Adams, DA Baerenwald, JP Zwerner, JA Zic, CM Eischen
Journal of Investigative Dermatology 134 (4), 1101-1107, 2014
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