Alessandro Borgia
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Extreme disorder in an ultrahigh-affinity protein complex
A Borgia, MB Borgia, K Bugge, VM Kissling, PO Heidarsson, ...
Nature 555 (7694), 61-66, 2018
Polymer scaling laws of unfolded and intrinsically disordered proteins quantified with single-molecule spectroscopy
H Hofmann, A Soranno, A Borgia, K Gast, D Nettels, B Schuler
Proceedings of the National Academy of Sciences 109 (40), 16155-16160, 2012
Single-molecule studies of protein folding
A Borgia, PM Williams, J Clarke
Annu. Rev. Biochem. 77 (1), 101-125, 2008
Single-molecule fluorescence reveals sequence-specific misfolding in multidomain proteins
MB Borgia, A Borgia, RB Best, A Steward, D Nettels, B Wunderlich, ...
Nature 474 (7353), 662-665, 2011
Experimental evidence for a frustrated energy landscape in a three-helix-bundle protein family
BG Wensley, S Batey, FAC Bone, ZM Chan, NR Tumelty, A Steward, ...
Nature 463 (7281), 685-688, 2010
Consistent view of polypeptide chain expansion in chemical denaturants from multiple experimental methods
A Borgia, W Zheng, K Buholzer, MB Borgia, A Schüler, H Hofmann, ...
Journal of the American Chemical Society 138 (36), 11714-11726, 2016
Localizing internal friction along the reaction coordinate of protein folding by combining ensemble and single-molecule fluorescence spectroscopy
A Borgia, BG Wensley, A Soranno, D Nettels, MB Borgia, A Hoffmann, ...
Nature communications 3 (1), 1195, 2012
Quantifying heterogeneity and conformational dynamics from single molecule FRET of diffusing molecules: recurrence analysis of single particles (RASP)
A Hoffmann, D Nettels, J Clark, A Borgia, SE Radford, J Clarke, B Schuler
Physical Chemistry Chemical Physics 13 (5), 1857-1871, 2011
Probing the action of chemical denaturant on an intrinsically disordered protein by simulation and experiment
W Zheng, A Borgia, K Buholzer, A Grishaev, B Schuler, RB Best
Journal of the American Chemical Society 138 (36), 11702-11713, 2016
Transient misfolding dominates multidomain protein folding
A Borgia, KR Kemplen, MB Borgia, A Soranno, S Shammas, B Wunderlich, ...
Nature communications 6 (1), 8861, 2015
Inferring properties of disordered chains from FRET transfer efficiencies
W Zheng, G Zerze, A Borgia, J Mittal, B Schuler, RB Best
Biophysical Journal 114 (3), 367a, 2018
Binding without folding–the biomolecular function of disordered polyelectrolyte complexes
B Schuler, A Borgia, MB Borgia, PO Heidarsson, ED Holmstrom, D Nettels, ...
Current opinion in structural biology 60, 66-76, 2020
Polyelectrolyte interactions enable rapid association and dissociation in high-affinity disordered protein complexes
A Sottini, A Borgia, MB Borgia, K Bugge, D Nettels, A Chowdhury, ...
Nature communications 11 (1), 5736, 2020
An Obligatory Intermediate in the Folding Pathway of Cytochromec552 from Hydrogenobacterthermophilus
C Travaglini-Allocatelli, S Gianni, VK Dubey, A Borgia, A Di Matteo, ...
Journal of Biological Chemistry 280 (27), 25729-25734, 2005
GPCR-mediated β-arrestin activation deconvoluted with single-molecule precision
WB Asher, DS Terry, GGA Gregorio, AW Kahsai, A Borgia, B Xie, A Modak, ...
Cell 185 (10), 1661-1675. e16, 2022
Release of linker histone from the nucleosome driven by polyelectrolyte competition with a disordered protein
PO Heidarsson, D Mercadante, A Sottini, D Nettels, MB Borgia, A Borgia, ...
Nature Chemistry 14 (2), 224-231, 2022
Comment on “Innovative scattering analysis shows that hydrophobic disordered proteins are expanded in water”
RB Best, W Zheng, A Borgia, K Buholzer, MB Borgia, H Hofmann, ...
Science 361 (6405), eaar7101, 2018
Tuning the Baird aromatic triplet-state energy of cyclooctatetraene to maximize the self-healing mechanism in organic fluorophores
AK Pati, O El Bakouri, S Jockusch, Z Zhou, RB Altman, GA Fitzgerald, ...
Proceedings of the National Academy of Sciences 117 (39), 24305-24315, 2020
Unveiling a hidden folding intermediate in c-type cytochromes by protein engineering
A Borgia, D Bonivento, C Travaglini-Allocatelli, A Di Matteo, M Brunori
Journal of Biological Chemistry 281 (14), 9331-9336, 2006
An effective strategy for the design of proteins with enhanced mechanical stability
A Borgia, A Steward, J Clarke
Angewandte Chemie (International ed. in English) 47 (36), 6900, 2008
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Articles 1–20