Danwei Huangfu
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Induction of pluripotent stem cells by defined factors is greatly improved by small-molecule compounds
D Huangfu, R Maehr, W Guo, A Eijkelenboom, M Snitow, AE Chen, ...
Nature biotechnology 26 (7), 795-797, 2008
Induction of pluripotent stem cells from primary human fibroblasts with only Oct4 and Sox2
D Huangfu, K Osafune, R Maehr, W Guo, A Eijkelenboom, S Chen, ...
Nature biotechnology 26 (11), 1269, 2008
Hedgehog signalling in the mouse requires intraflagellar transport proteins
D Huangfu, A Liu, AS Rakeman, NS Murcia, L Niswander, KV Anderson
Nature 426 (6962), 83-87, 2003
A small-molecule inhibitor of Tgf-β signaling replaces Sox2 in reprogramming by inducing Nanog
JK Ichida, J Blanchard, K Lam, EY Son, JE Chung, D Egli, KM Loh, ...
Cell stem cell 5 (5), 491-503, 2009
Cilia and Hedgehog responsiveness in the mouse
D Huangfu, KV Anderson
Proceedings of the National Academy of Sciences 102 (32), 11325-11330, 2005
Signaling from Smo to Ci/Gli: conservation and divergence of Hedgehog pathways from Drosophila to vertebrates
D Huangfu, KV Anderson
Development 133 (1), 3-14, 2006
An iCRISPR platform for rapid, multiplexable, and inducible genome editing in human pluripotent stem cells
F González, Z Zhu, ZD Shi, K Lelli, N Verma, QV Li, D Huangfu
Cell stem cell 15 (2), 215-226, 2014
All β cells contribute equally to islet growth and maintenance
K Brennand, D Huangfu, D Melton
PLoS biology 5 (7), 2007
Mouse Dispatched homolog1 is required for long-range, but not juxtacrine, Hh signaling
T Caspary, MJ Garcı́a-Garcı́a, D Huangfu, JT Eggenschwiler, MR Wyler, ...
Current biology 12 (18), 1628-1632, 2002
Human pluripotent stem cells: an emerging model in developmental biology
Z Zhu, D Huangfu
Development 140 (4), 705-717, 2013
Analysis of mouse embryonic patterning and morphogenesis by forward genetics
MJ García-García, JT Eggenschwiler, T Caspary, HL Alcorn, MR Wyler, ...
Proceedings of the National Academy of Sciences 102 (17), 5913-5919, 2005
Functional analysis of a chromosomal deletion associated with myelodysplastic syndromes using isogenic human induced pluripotent stem cells
AG Kotini, CJ Chang, I Boussaad, JJ Delrow, EK Dolezal, AB Nagulapally, ...
Nature biotechnology 33 (6), 646, 2015
CRISPR/Cas9-based engineering of the epigenome
J Pulecio, N Verma, E Mejía-Ramírez, D Huangfu, A Raya
Cell Stem Cell 21 (4), 431-447, 2017
Glucose and aging control the quiescence period that follows pancreatic beta cell replication
SJ Salpeter, AM Klein, D Huangfu, J Grimsby, Y Dor
Development 137 (19), 3205-3213, 2010
Genome editing of lineage determinants in human pluripotent stem cells reveals mechanisms of pancreatic development and diabetes
Z Zhu, QV Li, K Lee, BP Rosen, F González, CL Soh, D Huangfu
Cell stem cell 18 (6), 755-768, 2016
Homologous recombination DNA repair genes play a critical role in reprogramming to a pluripotent state
F González, D Georgieva, F Vanoli, ZD Shi, M Stadtfeld, T Ludwig, ...
Cell reports 3 (3), 651-660, 2013
A CRISPR/Cas-mediated selection-free knockin strategy in human embryonic stem cells
Z Zhu, N Verma, F González, ZD Shi, D Huangfu
Stem cell reports 4 (6), 1103-1111, 2015
The p53 family coordinates Wnt and nodal inputs in mesendodermal differentiation of embryonic stem cells
Q Wang, Y Zou, S Nowotschin, SY Kim, QV Li, CL Soh, J Su, C Zhang, ...
Cell stem cell 20 (1), 70-86, 2017
TET proteins safeguard bivalent promoters from de novo methylation in human embryonic stem cells
N Verma, H Pan, LC Doré, A Shukla, QV Li, B Pelham-Webb, V Teijeiro, ...
Nature genetics 50 (1), 83-95, 2018
The iCRISPR platform for rapid genome editing in human pluripotent stem cells
Z Zhu, F González, D Huangfu
Methods in enzymology 546, 215-250, 2014
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