| Cell-specific effects of RB or RB/p107 loss on retinal development implicate an intrinsically death-resistant cell-of-origin in retinoblastoma D Chen, I Livne-bar, JL Vanderluit, RS Slack, M Agochiya, R Bremner Cancer cell 5 (6), 539-551, 2004 | 326 | 2004 |
| E2f1–3 switch from activators in progenitor cells to repressors in differentiating cells JL Chong, PL Wenzel, MT Sáenz-Robles, V Nair, A Ferrey, JP Hagan, ... Nature 462 (7275), 930-934, 2009 | 282 | 2009 |
| Division and apoptosis of E2f-deficient retinal progenitors D Chen, M Pacal, P Wenzel, PS Knoepfler, G Leone, R Bremner Nature 462 (7275), 925-929, 2009 | 173 | 2009 |
| Minimal regions of chromosomal imbalance in retinoblastoma detected by comparative genomic hybridization D Chen, BL Gallie, JA Squire Cancer genetics and cytogenetics 129 (1), 57-63, 2001 | 117 | 2001 |
| Chx10 is required to block photoreceptor differentiation but is dispensable for progenitor proliferation in the postnatal retina I Livne-Bar, M Pacal, MC Cheung, M Hankin, J Trogadis, D Chen, ... Proceedings of the National Academy of Sciences 103 (13), 4988-4993, 2006 | 116 | 2006 |
| Unique requirement for Rb/E2F3 in neuronal migration: evidence for cell cycle-independent functions KA McClellan, VA Ruzhynsky, DN Douda, JL Vanderluit, KL Ferguson, ... Molecular and cellular biology 27 (13), 4825-4843, 2007 | 98 | 2007 |
| Rb-mediated neuronal differentiation through cell-cycle–independent regulation of E2f3a D Chen, R Opavsky, M Pacal, N Tanimoto, P Wenzel, MW Seeliger, ... PLoS biology 5 (7), e179, 2007 | 96 | 2007 |
| Minimal 16q Genomic Loss Implicates Cadherin-11 in Retinoblastoma MN Marchong, D Chen, TW Corson, C Lee, M Harmandayan, E Bowles, ... Molecular cancer research 2 (9), 495-503, 2004 | 92 | 2004 |
| Established and new mouse models reveal E2f1 and Cdk2 dependency of retinoblastoma, and expose effective strategies to block tumor initiation M Sangwan, SR McCurdy, I Livne-bar, M Ahmad, JL Wrana, D Chen, ... Oncogene 31 (48), 5019-5028, 2012 | 72 | 2012 |
| Genomic amplification in retinoblastoma narrowed to 0.6 megabase on chromosome 6p containing a kinesin-like gene, RBKIN D Chen, S Pajovic, A Duckett, VD Brown, JA Squire, BL Gallie Cancer Research 62 (4), 967-971, 2002 | 62 | 2002 |
| Retinal degeneration depends on Bmi1 function and reactivation of cell cycle proteins D Zencak, K Schouwey, D Chen, P Ekström, E Tanger, R Bremner, ... Proceedings of the National Academy of Sciences 110 (7), E593-E601, 2013 | 44 | 2013 |
| DZNep inhibits H3K27me3 deposition and delays retinal degeneration in the rd1 mice S Zheng, L Xiao, Y Liu, Y Wang, L Cheng, J Zhang, N Yan, D Chen Cell death & disease 9 (3), 310, 2018 | 43 | 2018 |
| Blue-light-blocking intraocular lens implantation improves the sleep quality of cataract patients X Wei, C She, D Chen, F Yan, J Zeng, L Zeng, L Wang Journal of Clinical Sleep Medicine 9 (8), 741-745, 2013 | 38 | 2013 |
| The RB protein family in retinal development and retinoblastoma: new insights from new mouse models R Bremner, D Chen, M Pacal, I Livne-Bar, M Agochiya Developmental neuroscience 26 (5-6), 417-434, 2005 | 35 | 2005 |
| E2f2 induces cone photoreceptor apoptosis independent of E2f1 and E2f3 D Chen, Y Chen, D Forrest, R Bremner Cell Death & Differentiation 20 (7), 931-940, 2013 | 30 | 2013 |
| The role of gut microbiome in autoimmune uveitis X Fu, Y Chen, D Chen Ophthalmic Research 64 (2), 168-177, 2021 | 28 | 2021 |
| The role of the microbiota in Graves’ disease and Graves’ orbitopathy J Hou, Y Tang, Y Chen, D Chen Frontiers in Cellular and Infection Microbiology 11, 739707, 2021 | 25 | 2021 |
| E2f1 mediates high glucose-induced neuronal death in cultured mouse retinal explants Y Wang, Y Zhou, L Xiao, S Zheng, N Yan, D Chen Cell cycle 16 (19), 1824-1834, 2017 | 25 | 2017 |
| Neogenin neutralization prevents photoreceptor loss in inherited retinal degeneration J Charish, AP Shabanzadeh, D Chen, P Mehlen, S Sethuramanujam, ... The Journal of Clinical Investigation 130 (4), 2054-2068, 2020 | 17 | 2020 |
| Ophthalmic artery occlusion after forehead autologous fat injection H Liu, D Chen, J Zhang Retinal Cases and Brief Reports 14 (3), 271-274, 2020 | 16 | 2020 |
