Doxorubicin encapsulated in liposomes containing surface‐bound polyethylene glycol: pharmacokinetics, tumor localization, and safety in patients with AIDS‐related Kaposi's sarcoma DW Northfelt, FJ Martin, P Working, PA Volberding, J Russell, M Newman, ... The Journal of Clinical Pharmacology 36 (1), 55-63, 1996 | 496 | 1996 |
Comparative pharmacokinetics, tissue distribution, and therapeutic effectiveness of cisplatin encapsulated in long-circulating, pegylated liposomes (SPI-077) in tumor-bearing mice MS Newman, GT Colbern, PK Working, C Engbers, MA Amantea Cancer chemotherapy and pharmacology 43, 1-7, 1999 | 350 | 1999 |
A phase I trial of intravenous CG7870, a replication-selective, prostate-specific antigen–targeted oncolytic adenovirus, for the treatment of hormone-refractory, metastatic … EJ Small, MA Carducci, JM Burke, R Rodriguez, L Fong, ... Molecular Therapy 14 (1), 107-117, 2006 | 310 | 2006 |
Pegylated liposomal doxorubicin: proof of principle using preclinical animal models and pharmacokinetic studies DM Vail, MA Amantea, GT Colbern, FJ Martin, RA Hilger, PK Working Seminars in oncology 31, 16-35, 2004 | 240 | 2004 |
Tissue distribution and therapeutic effect of intravenous free or encapsulated liposomal doxorubicin on human prostate carcinoma xenografts J Vaage, E Barberá‐Guillem, R Abra, A Huang, P Working Cancer 73 (5), 1478-1484, 1994 | 220 | 1994 |
Pharmacological-toxicological expert report. CAELYX^< TM>.(Stealth^(! R) liposomal doxorubicin HCl) PK Working Hum Exp. Toxicol. 15, 751-785, 1996 | 219 | 1996 |
Systemic and tumor disposition of platinum after administration of cisplatin or STEALTH liposomal-cisplatin formulations (SPI-077 and SPI-077 B103) in a preclinical tumor model … WC Zamboni, AC Gervais, MJ Egorin, JHM Schellens, EG Zuhowski, ... Cancer chemotherapy and pharmacology 53, 329-336, 2004 | 207 | 2004 |
Pathology of recombinant human transforming growth factor-β1 in rats and rabbits TG Terrell, PK Working, CP Chow, JD Green International Review of Experimental Pathology 34, 43-67, 1993 | 207 | 1993 |
Safety of poly (ethylene glycol) and poly (ethylene glycol) derivatives PK Working, MS Newman, J Johnson, JB Cornacoff | 195 | 1997 |
Pharmacokinetics, biodistribution and therapeutic efficacy of doxorubicin encapsulated in Stealth® liposomes (Doxil®) PK Working, MS Newman, SK Huang, E Mayhew, J Vaage, DD Lasic Journal of Liposome Research 4 (1), 667-687, 1994 | 195 | 1994 |
TAURINE AND HYPOTAURINE: THEIR EFFECTS ON MOTILITY, CAPACITATION AND THE ACROSOME REACTION OF HAMSTER SPERM IN VITRO AND … S Meizel, CW Lui, PK Working, RJ Mrsny Development, Growth & Differentiation 22 (3), 483-494, 1980 | 184 | 1980 |
Differences in the quality of semen in outdoor workers during summer and winter RJ Levine, RM Mathew, CB Chenault, MH Brown, ME Hurtt, KS Bentley, ... New England Journal of Medicine 323 (1), 12-16, 1990 | 182 | 1990 |
Male reproductive toxicology: comparison of the human to animal models. PK Working Environmental health perspectives 77, 37-44, 1988 | 182 | 1988 |
Use of primary cultures of human hepatocytes in toxicology studies BE Butterworth, T Smith-Oliver, L Earle, DJ Loury, RD White, DJ Doolittle, ... Cancer research 49 (5), 1075-1084, 1989 | 162 | 1989 |
Degeneration and regeneration of the olfactory epithelium following inhalation exposure to methyl bromide: pathology, cell kinetics, and olfactory function ME Hurtt, DA Thomas, PK Working, TM Monticello, KT Morgan Toxicology and applied pharmacology 94 (2), 311-328, 1988 | 158 | 1988 |
Reduction of the cardiotoxicity of doxorubicin in rabbits and dogs by encapsulation in long-circulating, pegylated liposomes PK Working, MS Newman, T Sullivan, J Yarrington Journal of Pharmacology and Experimental Therapeutics 289 (2), 1128-1133, 1999 | 149 | 1999 |
Sterically stabilized liposomes in cancer therapy and gene delivery. DD Lasic, JJ Vallner, PK Working Current opinion in molecular therapeutics 1 (2), 177-185, 1999 | 147 | 1999 |
Tumour uptake of doxorubicin in polyethylene glycol-coated liposomes and therapeutic effect against a xenografted human pancreatic carcinoma J Vaage, D Donovan, P Uster, P Working British journal of cancer 75 (4), 482-486, 1997 | 138 | 1997 |
Evidence that the fertilization envelope blocks sperm entry in eggs of Xenopus laevis: interaction of sperm with isolated envelopes RD Grey, PK Working, JL Hedrick Developmental Biology 54 (1), 52-60, 1976 | 122 | 1976 |
Oncolytic adenovirus CG7870 in combination with radiation demonstrates synergistic enhancements of antitumor efficacy without loss of specificity J Dilley, S Reddy, D Ko, N Nguyen, G Rojas, P Working, DC Yu Cancer Gene Therapy 12 (8), 715-722, 2005 | 114 | 2005 |