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Gopa Iyer
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Tumor mutational load predicts survival after immunotherapy across multiple cancer types
RM Samstein, CH Lee, AN Shoushtari, MD Hellmann, R Shen, ...
Nature genetics 51 (2), 202-206, 2019
30652019
Mutational landscape of metastatic cancer revealed from prospective clinical sequencing of 10,000 patients
A Zehir, R Benayed, RH Shah, A Syed, S Middha, HR Kim, P Srinivasan, ...
Nature medicine 23 (6), 703-713, 2017
29112017
OncoKB: a precision oncology knowledge base
D Chakravarty, J Gao, S Phillips, R Kundra, H Zhang, J Wang, ...
JCO precision oncology 1, 1-16, 2017
19292017
Intrinsic subtypes of high-grade bladder cancer reflect the hallmarks of breast cancer biology
JS Damrauer, KA Hoadley, DD Chism, C Fan, CJ Tiganelli, SE Wobker, ...
Proceedings of the national academy of sciences 111 (8), 3110-3115, 2014
8992014
Genome sequencing identifies a basis for everolimus sensitivity
G Iyer, AJ Hanrahan, MI Milowsky, H Al-Ahmadie, SN Scott, ...
Science 338 (6104), 221-221, 2012
7182012
HER kinase inhibition in patients with HER2-and HER3-mutant cancers
DM Hyman, SA Piha-Paul, H Won, J Rodon, C Saura, GI Shapiro, D Juric, ...
Nature 554 (7691), 189-194, 2018
6732018
Somatic ERCC2 Mutations Correlate with Cisplatin Sensitivity in Muscle-Invasive Urothelial Carcinoma
EM Van Allen, KW Mouw, P Kim, G Iyer, N Wagle, H Al-Ahmadie, C Zhu, ...
Cancer discovery 4 (10), 1140-1153, 2014
5762014
Convergent loss of PTEN leads to clinical resistance to a PI (3) Kα inhibitor
D Juric, P Castel, M Griffith, OL Griffith, HH Won, H Ellis, SH Ebbesen, ...
Nature 518 (7538), 240-244, 2015
5742015
Genome doubling shapes the evolution and prognosis of advanced cancers
CM Bielski, A Zehir, AV Penson, MTA Donoghue, W Chatila, J Armenia, ...
Nature genetics 50 (8), 1189-1195, 2018
4772018
Alterations in DNA damage response and repair genes as potential marker of clinical benefit from PD-1/PD-L1 blockade in advanced urothelial cancers
MY Teo, K Seier, I Ostrovnaya, AM Regazzi, BE Kania, MM Moran, ...
Journal of Clinical Oncology 36 (17), 1685, 2018
4502018
Prevalence and co-occurrence of actionable genomic alterations in high-grade bladder cancer
G Iyer, H Al-Ahmadie, N Schultz, AJ Hanrahan, I Ostrovnaya, AV Balar, ...
Journal of Clinical Oncology 31 (25), 3133, 2013
3272013
Next-generation sequencing of nonmuscle invasive bladder cancer reveals potential biomarkers and rational therapeutic targets
EJ Pietzak, A Bagrodia, EK Cha, EN Drill, G Iyer, S Isharwal, I Ostrovnaya, ...
European urology 72 (6), 952-959, 2017
3092017
Contribution of systemic and somatic factors to clinical response and resistance to PD-L1 blockade in urothelial cancer: an exploratory multi-omic analysis
A Snyder, T Nathanson, SA Funt, A Ahuja, J Buros Novik, MD Hellmann, ...
PLoS medicine 14 (5), e1002309, 2017
2852017
DNA damage response and repair gene alterations are associated with improved survival in patients with platinum-treated advanced urothelial carcinoma
MY Teo, RM Bambury, EC Zabor, E Jordan, H Al-Ahmadie, ME Boyd, ...
Clinical cancer research 23 (14), 3610-3618, 2017
2432017
Genomic characterization of upper tract urothelial carcinoma
JP Sfakianos, EK Cha, G Iyer, SN Scott, EC Zabor, RH Shah, Q Ren, ...
European urology 68 (6), 970-977, 2015
2342015
BRAF mutation is associated with early stage disease and improved outcome in patients with low‐grade serous ovarian cancer
RN Grisham, G Iyer, K Garg, D DeLair, DM Hyman, Q Zhou, A Iasonos, ...
Cancer 119 (3), 548-554, 2013
2202013
Clonal relatedness and mutational differences between upper tract and bladder urothelial carcinoma
F Audenet, S Isharwal, EK Cha, MTA Donoghue, EN Drill, I Ostrovnaya, ...
Clinical Cancer Research 25 (3), 967-976, 2019
1942019
Phase II study of everolimus in metastatic urothelial cancer
MI Milowsky, G Iyer, AM Regazzi, H Al-Ahmadie, SR Gerst, I Ostrovnaya, ...
BJU international 112 (4), 462, 2013
1862013
Frequent somatic CDH1 loss-of-function mutations in plasmacytoid variant bladder cancer
HA Al-Ahmadie, G Iyer, BH Lee, SN Scott, R Mehra, A Bagrodia, ...
Nature genetics 48 (4), 356-358, 2016
1762016
Genomic predictors of survival in patients with high-grade urothelial carcinoma of the bladder
PH Kim, EK Cha, JP Sfakianos, G Iyer, EC Zabor, SN Scott, I Ostrovnaya, ...
European urology 67 (2), 198-201, 2015
1632015
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