Design, synthesis and biological evaluation of novel quinazoline derivatives as potential antitumor agents: molecular docking study AS El-Azab, MA Al-Omar, AM Alaa, NI Abdel-Aziz, AA Magda, AM Aleisa, ... European journal of medicinal chemistry 45 (9), 4188-4198, 2010 | 288 | 2010 |
Substituted quinazolines, part 3. Synthesis, in vitro antitumor activity and molecular modeling study of certain 2-thieno-4 (3H)-quinazolinone analogs AM Al-Obaid, SG Abdel-Hamide, HA El-Kashef, AM Alaa, AS El-Azab, ... European journal of medicinal chemistry 44 (6), 2379-2391, 2009 | 216 | 2009 |
Design, synthesis, and biological evaluation of substituted hydrazone and pyrazole derivatives as selective COX-2 inhibitors: Molecular docking study AA Magda, NI Abdel-Aziz, AM Alaa, AS El-Azab, YA Asiri, KEH ElTahir Bioorganic & medicinal chemistry 19 (11), 3416-3424, 2011 | 181 | 2011 |
Synthesis, biological evaluation and molecular modeling study of pyrazole and pyrazoline derivatives as selective COX-2 inhibitors and anti-inflammatory agents. Part 2 AA Magda, NI Abdel-Aziz, AM Alaa, AS El-Azab, KEH ElTahir Bioorganic & medicinal chemistry 20 (10), 3306-3316, 2012 | 171 | 2012 |
Non-classical antifolates. Part 2: synthesis, biological evaluation, and molecular modeling study of some new 2, 6-substituted-quinazolin-4-ones FAM Al-Omary, LA Abou-Zeid, MN Nagi, ESE Habib, AM Alaa, AS El-Azab, ... Bioorganic & medicinal chemistry 18 (8), 2849-2863, 2010 | 163 | 2010 |
Structure-based design of phthalimide derivatives as potential cyclooxygenase-2 (COX-2) inhibitors: anti-inflammatory and analgesic activities AM Alanazi, AS El-Azab, IA Al-Suwaidan, KEH ElTahir, YA Asiri, ... European journal of medicinal chemistry 92, 115-123, 2015 | 130 | 2015 |
Synthesis and anticonvulsant evaluation of some new 2, 3, 8-trisubstituted-4 (3H)-quinazoline derivatives AS El-Azab, KEH ElTahir Bioorganic & medicinal chemistry letters 22 (1), 327-333, 2012 | 104 | 2012 |
Design and synthesis of novel 7-aminoquinazoline derivatives: Antitumor and anticonvulsant activities AS El-Azab, KEH ElTahir Bioorganic & medicinal chemistry letters 22 (5), 1879-1885, 2012 | 101 | 2012 |
Synthesis, anti-inflammatory, analgesic, COX-1/2 inhibitory activities and molecular docking studies of substituted 2-mercapto-4 (3H)-quinazolinones AM Alaa, LA Abou-Zeid, KEH ElTahir, RR Ayyad, AA Magda, AS El-Azab European Journal of Medicinal Chemistry 121, 410-421, 2016 | 100 | 2016 |
Synthesis and antitumor evaluation of trimethoxyanilides based on 4 (3H)-quinazolinone scaffolds MA Mohamed, RR Ayyad, TZ Shawer, AM Alaa, AS El-Azab European journal of medicinal chemistry 112, 106-113, 2016 | 90 | 2016 |
Design, synthesis of 2, 3-disubstitued 4 (3H)-quinazolinone derivatives as anti-inflammatory and analgesic agents: COX-1/2 inhibitory activities and molecular docking studies AM Alaa, LA Abou-Zeid, KEH ElTahir, MA Mohamed, MAA El-Enin, ... Bioorganic & Medicinal Chemistry 24 (16), 3818-3828, 2016 | 77 | 2016 |
Synthesis, antitumor activity and molecular docking study of some novel 3-benzyl-4 (3H) quinazolinone analogues IA Al-Suwaidan, AAM Abdel-Aziz, TZ Shawer, RR Ayyad, AM Alanazi, ... Journal of enzyme inhibition and medicinal chemistry 31 (1), 78-89, 2016 | 76 | 2016 |
Synthesis and biological evaluation of some novel cyclic-imides as hypoglycaemic, anti-hyperlipidemic agents AM Alaa, AS El-Azab, SM Attia, AM Al-Obaid, MA Al-Omar, HI El-Subbagh European journal of medicinal chemistry 46 (9), 4324-4329, 2011 | 73 | 2011 |
Design, synthesis and biological evaluation of some novel substituted quinazolines as antitumor agents AM Alanazi, AM Alaa, IA Al-Suwaidan, SG Abdel-Hamide, TZ Shawer, ... European journal of medicinal chemistry 79, 446-454, 2014 | 72 | 2014 |
Design, synthesis and biological evaluation of 2-mercapto-3-phenethylquinazoline bearing anilide fragments as potential antitumor agents: molecular docking study IA Al-Suwaidan, AM Alanazi, AM Alaa, MA Mohamed, AS El-Azab Bioorganic & medicinal chemistry letters 23 (13), 3935-3941, 2013 | 71 | 2013 |
Synthesis and anti-inflammatory activity of sulfonamides and carboxylates incorporating trimellitimides: dual cyclooxygenase/carbonic anhydrase inhibitory actions AM Alaa, A Angeli, AS El-Azab, MEA Hammouda, MA El-Sherbeny, ... Bioorganic chemistry 84, 260-268, 2019 | 65 | 2019 |
Acacia Senegal gum exudate offers protection against cyclophosphamide-induced urinary bladder cytotoxicity AA Al-Yahya, AA Al-Majed, AM Gado, MH Daba, OA Al-Shabanah, ... Oxidative medicine and cellular longevity 2, 207-213, 2009 | 65 | 2009 |
Synthesis and potential antitumor activity of 7-(4-substituted piperazin-1-yl)-4-oxoquinolines based on ciprofloxacin and norfloxacin scaffolds: in silico studies AAM Abdel-Aziz, AS El-Azab, AM Alanazi, YA Asiri, IA Al-Suwaidan, ... Journal of Enzyme Inhibition and Medicinal Chemistry 31 (5), 796-809, 2016 | 64 | 2016 |
Molecular design, synthesis and biological evaluation of cyclic imides bearing benzenesulfonamide fragment as potential COX-2 inhibitors. Part 2 IA Al-Suwaidan, AM Alanazi, AS El-Azab, AM Al-Obaid, KEH ElTahir, ... Bioorganic & medicinal chemistry letters 23 (9), 2601-2605, 2013 | 64 | 2013 |
Synthesis, anti-inflammatory, analgesic and COX-1/2 inhibition activities of anilides based on 5, 5-diphenylimidazolidine-2, 4-dione scaffold: molecular docking studies AM Alaa, AS El-Azab, LA Abou-Zeid, KEH ElTahir, NI Abdel-Aziz, ... European journal of medicinal chemistry 115, 121-131, 2016 | 62 | 2016 |