DNA methylation inhibitor 5-Aza-2′-deoxycytidine induces reversible genome-wide DNA damage that is distinctly influenced by DNA methyltransferases 1 and 3B SS Palii, BO Van Emburgh, UT Sankpal, KD Brown, KD Robertson Molecular and cellular biology 28 (2), 752-771, 2008 | 445 | 2008 |
Sulforaphane-induced G2/M phase cell cycle arrest involves checkpoint kinase 2-mediated phosphorylation of cell division cycle 25C SV Singh, A Herman-Antosiewicz, AV Singh, KL Lew, SK Srivastava, ... Journal of Biological Chemistry 279 (24), 25813-25822, 2004 | 399 | 2004 |
Dissociation of centrosome replication events from cycles of DNA synthesis and mitotic division in hydroxyurea-arrested Chinese hamster ovary cells. R Balczon, L Bao, WE Zimmer, K Brown, RP Zinkowski, BR Brinkley The Journal of cell biology 130 (1), 105-115, 1995 | 378 | 1995 |
Atm deficiency results in severe meiotic disruption as early as leptonema of prophase I C Barlow, M Liyanage, PB Moens, M Tarsounas, K Nagashima, K Brown, ... Development 125 (20), 4007-4017, 1998 | 351 | 1998 |
Atm selectively regulates distinct p53-dependent cell-cycle checkpoint and apoptotic pathways C Barlow, KD Brown, CX Deng, DA Tagle, A Wynshaw-Boris Nature genetics 17 (4), 453-456, 1997 | 261 | 1997 |
The mismatch repair system is required for S-phase checkpoint activation KD Brown, A Rathi, R Kamath, DI Beardsley, Q Zhan, JL Mannino, ... Nature genetics 33 (1), 80-84, 2003 | 257 | 2003 |
Sonic hedgehog is an autocrine viability factor for myofibroblastic hepatic stellate cells L Yang, Y Wang, H Mao, S Fleig, A Omenetti, KD Brown, JK Sicklick, YX Li, ... Journal of hepatology 48 (1), 98-106, 2008 | 233 | 2008 |
Inactivation of Wnt inhibitory factor-1 (WIF1) expression by epigenetic silencing is a common event in breast cancer L Ai, Q Tao, S Zhong, CR Fields, WJ Kim, MW Lee, Y Cui, KD Brown, ... Carcinogenesis 27 (7), 1341-1348, 2006 | 223 | 2006 |
The ataxia-telangiectasia gene product, a constitutively expressed nuclear protein that is not up-regulated following genome damage KD Brown, Y Ziv, SN Sadanandan, L Chessa, FS Collins, Y Shiloh, ... Proceedings of the National Academy of Sciences 94 (5), 1840-1845, 1997 | 216 | 1997 |
ATM is a cytoplasmic protein in mouse brain required to prevent lysosomal accumulation C Barlow, C Ribaut-Barassin, TA Zwingman, AJ Pope, KD Brown, ... Proceedings of the National Academy of Sciences 97 (2), 871-876, 2000 | 211 | 2000 |
Bilingual Education. CR Baker, K Brown Encyclopedia of Language and Linguistics: 2nd ed, 772-780, 2005 | 205 | 2005 |
Differential signaling and tumor necrosis factor receptor–associated factor (Traf) degradation mediated by Cd40 and the Epstein-Barr virus oncoprotein latent membrane protein 1 … KD Brown, BS Hostager, GA Bishop The Journal of experimental medicine 193 (8), 943-954, 2001 | 205 | 2001 |
Ataxia telangiectasia mutated is essential during adult neurogenesis DM Allen, H van Praag, J Ray, Z Weaver, CJ Winrow, TA Carter, ... Genes & development 15 (5), 554-566, 2001 | 202 | 2001 |
Accumulation of hedgehog-responsive progenitors parallels alcoholic liver disease severity in mice and humans Y Jung, KD Brown, RP Witek, A Omenetti, L Yang, M Vandongen, ... Gastroenterology 134 (5), 1532-1543. e3, 2008 | 190 | 2008 |
Bisulfite sequencing of DNA RP Darst, CE Pardo, L Ai, KD Brown, MP Kladde Current protocols in molecular biology 91 (1), 7.9. 1-7.9. 17, 2010 | 178 | 2010 |
Cyclin-like accumulation and loss of the putative kinetochore motor CENP-E results from coupling continuous synthesis with specific degradation at the end of mitosis. KD Brown, RM Coulson, TJ Yen, DW Cleveland The Journal of cell biology 125 (6), 1303-1312, 1994 | 176 | 1994 |
The hedgehog pathway regulates remodelling responses to biliary obstruction in rats A Omenetti, Y Popov, Y Jung, SS Choi, RP Witek, L Yang, KD Brown, ... Gut 57 (9), 1275-1282, 2008 | 150 | 2008 |
Ataxia-telangiectasia: founder effect among north African Jews S Gilad, A Bar-Shira, R Harnik, D Shkedy, Y Ziv, R Khosravi, K Brown, ... Human Molecular Genetics 5 (12), 2033-2037, 1996 | 143 | 1996 |
Regulation of TRAF2 signaling by self-induced degradation KD Brown, BS Hostager, GA Bishop Journal of Biological Chemistry 277 (22), 19433-19438, 2002 | 142 | 2002 |
High-quality gene assembly directly from unpurified mixtures of microarray-synthesized oligonucleotides AY Borovkov, AV Loskutov, MD Robida, KM Day, JA Cano, T Le Olson, ... Nucleic acids research 38 (19), e180-e180, 2010 | 139 | 2010 |