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JosÚ L. McFaline-Figueroa
JosÚ L. McFaline-Figueroa
Assistant Professor of Biomedical Engineering, Columbia University
Verified email at columbia.edu - Homepage
Title
Cited by
Cited by
Year
DNA damage induced by chronic inflammation contributes to colon carcinogenesis in mice
LB Meira, JM Bugni, SL Green, CW Lee, B Pang, D Borenshtein, ...
The Journal of clinical investigation 118 (7), 2516-2525, 2008
5942008
Joint profiling of chromatin accessibility and gene expression in thousands of single cells
J Cao, DA Cusanovich, V Ramani, D Aghamirzaie, HA Pliner, AJ Hill, ...
Science 361 (6409), 1380-1385, 2018
5532018
Cicero predicts cis-regulatory DNA interactions from single-cell chromatin accessibility data
HA Pliner, JS Packer, JL McFaline-Figueroa, DA Cusanovich, RM Daza, ...
Molecular cell 71 (5), 858-871. e8, 2018
4182018
A genome-wide framework for mapping gene regulation via cellular genetic screens
M Gasperini, AJ Hill, JL McFaline-Figueroa, B Martin, S Kim, MD Zhang, ...
Cell 176 (1-2), 377-390. e19, 2019
3572019
Gut microbes define liver cancer risk in mice exposed to chemical and viral transgenic hepatocarcinogens
JG Fox, Y Feng, EJ Theve, AR Raczynski, JLA Fiala, AL Doernte, ...
Gut 59 (01), 88-97, 2010
2462010
Infection-induced colitis in mice causes dynamic and tissue-specific changes in stress response and DNA damage leading to colon cancer
A Mangerich, CG Knutson, NM Parry, S Muthupalani, W Ye, E Prestwich, ...
Proceedings of the National Academy of Sciences 109 (27), E1820-E1829, 2012
2372012
Dynamics of Gene Expression in Single Root Cells of Arabidopsis thaliana
K Jean-Baptiste, JL McFaline-Figueroa, CM Alexandre, MW Dorrity, ...
The plant cell 31 (5), 993-1011, 2019
2182019
Continuous elimination of oxidized nucleotides is necessary to prevent rapid onset of cellular senescence
P Rai, TT Onder, JJ Young, JL McFaline, B Pang, PC Dedon, ...
Proceedings of the National Academy of Sciences 106 (1), 169-174, 2009
2122009
Defects in purine nucleotide metabolism lead to substantial incorporation of xanthine and hypoxanthine into DNA and RNA
B Pang, JL McFaline, NE Burgis, M Dong, K Taghizadeh, MR Sullivan, ...
Proceedings of the National Academy of Sciences 109 (7), 2319-2324, 2012
1842012
Massively multiplex chemical transcriptomics at single-cell resolution
SR Srivatsan, JL McFaline-Figueroa, V Ramani, L Saunders, J Cao, ...
Science 367 (6473), 45-51, 2020
1472020
Quantification of DNA damage products resulting from deamination, oxidation and reaction with products of lipid peroxidation by liquid chromatography isotope dilution tandemá…
K Taghizadeh, JL McFaline, B Pang, M Sullivan, M Dong, E Plummer, ...
Nature protocols 3 (8), 1287-1298, 2008
1392008
On the design of CRISPR-based single-cell molecular screens
AJ Hill, JL McFaline-Figueroa, LM Starita, MJ Gasperini, KA Matreyek, ...
Nature methods 15 (4), 271-274, 2018
1272018
A pooled single-cell genetic screen identifies regulatory checkpoints in the continuum of the epithelial-to-mesenchymal transition
JL McFaline-Figueroa, AJ Hill, X Qiu, D Jackson, J Shendure, C Trapnell
Nature genetics 51 (9), 1389-1398, 2019
1182019
Minor Changes in Expression of the Mismatch Repair Protein MSH2 Exert a Major Impact on Glioblastoma Response to TemozolomideMinor Decreases in MSH2 Mediate Chemoresistance
JL McFaline-Figueroa, CJ Braun, M Stanciu, ZD Nagel, P Mazzucato, ...
Cancer research 75 (15), 3127-3138, 2015
1042015
Inferring causal gene regulatory networks from coupled single-cell expression dynamics using Scribe
X Qiu, A Rahimzamani, L Wang, B Ren, Q Mao, T Durham, ...
Cell systems 10 (3), 265-274. e11, 2020
93*2020
Thyroid hormone regulates distinct paths to maturation in pigment cell lineages
LM Saunders, AK Mishra, AJ Aman, VM Lewis, MB Toomey, JS Packer, ...
Elife 8, e45181, 2019
782019
Integrated molecular analysis indicates undetectable change in DNA damage in mice after continuous irradiation at~ 400-fold natural background radiation
W Olipitz, D Wiktor-Brown, J Shuga, B Pang, J McFaline, P Lonkar, ...
Environmental health perspectives 120 (8), 1130-1136, 2012
552012
A rapid survival assay to measure drug-induced cytotoxicity and cell cycle effects
C Valiathan, JL McFaline, LD Samson
DNA repair 11 (1), 92-98, 2012
262012
Targeting TWIST 1 through loss of function inhibits tumorigenicity of human glioblastoma
AM Mikheev, SA Mikheeva, LJ Severs, CC Funk, L Huang, ...
Molecular oncology 12 (7), 1188-1202, 2018
252018
Surveying the damage: the challenges of developing nucleic acid biomarkers of inflammation
J Son, B Pang, JL McFaline, K Taghizadeh, PC Dedon
Molecular BioSystems 4 (9), 902-908, 2008
252008
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