Rational Targeting of Active Site Tyrosine Residues using Sulfonyl Fluoride Probes EC Hett, H Xu, KF Geoghegan, A Gopalsamy, RE Kyne, CA Menard, ... ACS chemical biology, 2015 | 163 | 2015 |
Reversible acetylation and inactivation of Mycobacterium tuberculosis acetyl-CoA synthetase is dependent on cAMP H Xu, SS Hegde, JS Blanchard Biochemistry 50 (26), 5883-5892, 2011 | 129 | 2011 |
Synthesis and in vitro antimycobacterial activity of B-ring modified diaryl ether InhA inhibitors CW am Ende, SE Knudson, N Liu, J Childs, TJ Sullivan, M Boyne, H Xu, ... Bioorganic & medicinal chemistry letters 18 (10), 3029-3033, 2008 | 102 | 2008 |
NXL104 Irreversibly Inhibits the β-Lactamase from Mycobacterium tuberculosis H Xu, S Hazra, JS Blanchard Biochemistry 51 (22), 4551-4557, 2012 | 90 | 2012 |
Mechanism and Inhibition of saFabI, the Enoyl Reductase from Staphylococcus aureus† H Xu, TJ Sullivan, J Sekiguchi, T Kirikae, I Ojima, CF Stratton, W Mao, ... Biochemistry 47 (14), 4228-4236, 2008 | 82 | 2008 |
Structures of the Michaelis complex (1.2 Å) and the covalent acyl intermediate (2.0 Å) of cefamandole bound in the active sites of the Mycobacterium tuberculosis β-lactamase … LW Tremblay, H Xu, JS Blanchard Biochemistry 49 (45), 9685-9687, 2010 | 65 | 2010 |
Tebipenem, a New Carbapenem Antibiotic is a Slow Substrate that Inhibits the β-Lactamase from Mycobacterium tuberculosis S Hazra, H Xu, JS Blanchard Biochemistry, 2014 | 50 | 2014 |
Potential of Lichen Secondary Metabolites against Plasmodium Liver Stage Parasites with FAS-II as the Potential Target IL Lauinger, L Vivas, R Perozzo, C Stairiker, A Tarun, M Zloh, X Zhang, ... Journal of natural products 76 (6), 1064-1070, 2013 | 45 | 2013 |
Mechanism and regulation of mycobactin fatty acyl-AMP ligase FadD33 O Vergnolle, H Xu, JS Blanchard Journal of Biological Chemistry 288 (39), 28116-28125, 2013 | 43 | 2013 |
Kinetic Characterization of Hydrolysis of Nitrocefin, Cefoxitin, and Meropenem by β-Lactamase from Mycobacterium tuberculosis C Chow, H Xu, JS Blanchard Biochemistry 52 (23), 4097-4104, 2013 | 31 | 2013 |
Synthesis of 4-phenoxybenzamide adenine dinucleotide as NAD analogue with inhibitory activity against enoyl-ACP reductase (InhA) of Mycobacterium tuberculosis L Bonnac, GY Gao, L Chen, K Felczak, EM Bennett, H Xu, TS Kim, N Liu, ... Bioorganic & medicinal chemistry letters 17 (16), 4588-4591, 2007 | 30 | 2007 |
Metallic samarium and iodine promoted facile and efficient syntheses of trisubstituted alkenes from the acetates of Baylis–Hillman adducts J Li, H Xu, Y Zhang Tetrahedron letters 46 (11), 1931-1934, 2005 | 30 | 2005 |
A novel interaction linking the FAS-II and phthiocerol dimycocerosate (PDIM) biosynthetic pathways NA Kruh, JG Borgaro, BP Ruzsicska, H Xu, PJ Tonge Journal of Biological Chemistry 283 (46), 31719-31725, 2008 | 20 | 2008 |
Acetylation of acetyl-CoA synthetase from< i> Mycobacterium tuberculosis</i> leads to specific inactivation of the adenylation reaction T Noy, H Xu, JS Blanchard Archives of biochemistry and biophysics 550, 42-49, 2014 | 19 | 2014 |
A library approach to rapidly discover photoaffinity probes of the mRNA decapping scavenger enzyme DcpS H Xu, EC Hett, A Gopalsamy, MD Parikh, KF Geoghegan, RE Kyne, ... Molecular BioSystems, 2015 | 12 | 2015 |
Click chemistry patents and their impact on drug discovery and chemical biology H Xu, LH Jones Pharmaceutical patent analyst 4 (2), 109-119, 2015 | 7 | 2015 |