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Hua Xu
Hua Xu
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Cited by
Cited by
Year
Rational Targeting of Active Site Tyrosine Residues using Sulfonyl Fluoride Probes
EC Hett, H Xu, KF Geoghegan, A Gopalsamy, RE Kyne, CA Menard, ...
ACS chemical biology, 2015
1632015
Reversible acetylation and inactivation of Mycobacterium tuberculosis acetyl-CoA synthetase is dependent on cAMP
H Xu, SS Hegde, JS Blanchard
Biochemistry 50 (26), 5883-5892, 2011
1292011
Synthesis and in vitro antimycobacterial activity of B-ring modified diaryl ether InhA inhibitors
CW am Ende, SE Knudson, N Liu, J Childs, TJ Sullivan, M Boyne, H Xu, ...
Bioorganic & medicinal chemistry letters 18 (10), 3029-3033, 2008
1022008
NXL104 Irreversibly Inhibits the β-Lactamase from Mycobacterium tuberculosis
H Xu, S Hazra, JS Blanchard
Biochemistry 51 (22), 4551-4557, 2012
902012
Mechanism and Inhibition of saFabI, the Enoyl Reductase from Staphylococcus aureus†
H Xu, TJ Sullivan, J Sekiguchi, T Kirikae, I Ojima, CF Stratton, W Mao, ...
Biochemistry 47 (14), 4228-4236, 2008
822008
Structures of the Michaelis complex (1.2 Å) and the covalent acyl intermediate (2.0 Å) of cefamandole bound in the active sites of the Mycobacterium tuberculosis β-lactamase …
LW Tremblay, H Xu, JS Blanchard
Biochemistry 49 (45), 9685-9687, 2010
652010
Tebipenem, a New Carbapenem Antibiotic is a Slow Substrate that Inhibits the β-Lactamase from Mycobacterium tuberculosis
S Hazra, H Xu, JS Blanchard
Biochemistry, 2014
502014
Potential of Lichen Secondary Metabolites against Plasmodium Liver Stage Parasites with FAS-II as the Potential Target
IL Lauinger, L Vivas, R Perozzo, C Stairiker, A Tarun, M Zloh, X Zhang, ...
Journal of natural products 76 (6), 1064-1070, 2013
452013
Mechanism and regulation of mycobactin fatty acyl-AMP ligase FadD33
O Vergnolle, H Xu, JS Blanchard
Journal of Biological Chemistry 288 (39), 28116-28125, 2013
432013
Kinetic Characterization of Hydrolysis of Nitrocefin, Cefoxitin, and Meropenem by β-Lactamase from Mycobacterium tuberculosis
C Chow, H Xu, JS Blanchard
Biochemistry 52 (23), 4097-4104, 2013
312013
Synthesis of 4-phenoxybenzamide adenine dinucleotide as NAD analogue with inhibitory activity against enoyl-ACP reductase (InhA) of Mycobacterium tuberculosis
L Bonnac, GY Gao, L Chen, K Felczak, EM Bennett, H Xu, TS Kim, N Liu, ...
Bioorganic & medicinal chemistry letters 17 (16), 4588-4591, 2007
302007
Metallic samarium and iodine promoted facile and efficient syntheses of trisubstituted alkenes from the acetates of Baylis–Hillman adducts
J Li, H Xu, Y Zhang
Tetrahedron letters 46 (11), 1931-1934, 2005
302005
A novel interaction linking the FAS-II and phthiocerol dimycocerosate (PDIM) biosynthetic pathways
NA Kruh, JG Borgaro, BP Ruzsicska, H Xu, PJ Tonge
Journal of Biological Chemistry 283 (46), 31719-31725, 2008
202008
Acetylation of acetyl-CoA synthetase from< i> Mycobacterium tuberculosis</i> leads to specific inactivation of the adenylation reaction
T Noy, H Xu, JS Blanchard
Archives of biochemistry and biophysics 550, 42-49, 2014
192014
A library approach to rapidly discover photoaffinity probes of the mRNA decapping scavenger enzyme DcpS
H Xu, EC Hett, A Gopalsamy, MD Parikh, KF Geoghegan, RE Kyne, ...
Molecular BioSystems, 2015
122015
Click chemistry patents and their impact on drug discovery and chemical biology
H Xu, LH Jones
Pharmaceutical patent analyst 4 (2), 109-119, 2015
72015
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