| Restoration of vision in RPE65-deficient Briard dogs using an AAV serotype 4 vector that specifically targets the retinal pigmented epithelium G Le Meur, K Stieger, AJ Smith, M Weber, JY Deschamps, D Nivard, ... Gene therapy 14 (4), 292-303, 2007 | 256 | 2007 |
| Long-term microdystrophin gene therapy is effective in a canine model of Duchenne muscular dystrophy C Le Guiner, L Servais, M Montus, T Larcher, B Fraysse, S Moullec, ... Nature communications 8 (1), 16105, 2017 | 228 | 2017 |
| History of xenotransplantation JY Deschamps, FA Roux, P Saï, E Gouin Xenotransplantation 12 (2), 91-109, 2005 | 212 | 2005 |
| Forelimb treatment in a large cohort of dystrophic dogs supports delivery of a recombinant AAV for exon skipping in Duchenne patients C Le Guiner, M Montus, L Servais, Y Cherel, V Francois, JL Thibaud, ... Molecular Therapy 22 (11), 1923-1935, 2014 | 133 | 2014 |
| Long-term doxycycline-regulated transgene expression in the retina of nonhuman primates following subretinal injection of recombinant AAV vectors K Stieger, G Le Meur, F Lasne, M Weber, JY Deschamps, D Nivard, ... Molecular Therapy 13 (5), 967-975, 2006 | 131 | 2006 |
| Systemic delivery of allogenic muscle stem cells induces long-term muscle repair and clinical efficacy in duchenne muscular dystrophy dogs K Rouger, T Larcher, L Dubreil, JY Deschamps, C Le Guiner, G Jouvion, ... The American journal of pathology 179 (5), 2501-2518, 2011 | 128 | 2011 |
| Biodistribution of rAAV vectors following intraocular administration: evidence for the presence and persistence of vector DNA in the optic nerve and in the brain N Provost, G Le Meur, M Weber, A Mendes-Madeira, G Podevin, Y Cherel, ... Molecular Therapy 11 (2), 275-283, 2005 | 107 | 2005 |
| Tolerogenic dendritic cells actively inhibit T cells through heme oxygenase‐1 in rodents and in nonhuman primates A Moreau, M Hill, P Thebault, JY Deschamps, E Chiffoleau, C Chauveau, ... The FASEB Journal 23 (9), 3070-3077, 2009 | 105 | 2009 |
| Safety and efficacy of regional intravenous (ri) versus intramuscular (im) delivery of rAAV1 and rAAV8 to nonhuman primate skeletal muscle A Toromanoff, Y Chérel, M Guilbaud, M Penaud-Budloo, RO Snyder, ... Molecular Therapy 16 (7), 1291-1299, 2008 | 103 | 2008 |
| Xenotransfusions, past and present FA Roux, P Saï, JY Deschamps Xenotransplantation 14 (3), 208-216, 2007 | 102 | 2007 |
| Detection of intact rAAV particles up to 6 years after successful gene transfer in the retina of dogs and primates K Stieger, J Schroeder, N Provost, A Mendes-Madeira, B Belbellaa, ... Molecular Therapy 17 (3), 516-523, 2009 | 101 | 2009 |
| Subretinal delivery of recombinant AAV serotype 8 vector in dogs results in gene transfer to neurons in the brain K Stieger, MA Colle, L Dubreil, A Mendes-Madeira, M Weber, G Le Meur, ... Molecular Therapy 16 (5), 916-923, 2008 | 94 | 2008 |
| Capsid-specific removal of circulating antibodies to adeno-associated virus vectors B Bertin, P Veron, C Leborgne, JY Deschamps, S Moullec, Y Fromes, ... Scientific reports 10 (1), 864, 2020 | 87 | 2020 |
| Intracerebral gene therapy using AAVrh. 10-hARSA recombinant vector to treat patients with early-onset forms of metachromatic leukodystrophy: preclinical feasibility and safety … M Zerah, F Piguet, MA Colle, S Raoul, JY Deschamps, J Deniaud, ... Human Gene Therapy Clinical Development 26 (2), 113-124, 2015 | 86 | 2015 |
| Successful gene therapy in the RPGRIP1-deficient dog: a large model of cone–rod dystrophy E Lhériteau, L Petit, M Weber, G Le Meur, JY Deschamps, L Libeau, ... Molecular therapy 22 (2), 265-277, 2014 | 77 | 2014 |
| Restoration of vision in the pde6β-deficient dog, a large animal model of rod-cone dystrophy L Petit, E Lhériteau, M Weber, G Le Meur, JY Deschamps, N Provost, ... Molecular therapy 20 (11), 2019-2030, 2012 | 72 | 2012 |
| Lack of immunotoxicity after regional intravenous (RI) delivery of rAAV to nonhuman primate skeletal muscle A Toromanoff, O Adjali, T Larcher, M Hill, L Guigand, P Chenuaud, ... Molecular Therapy 18 (1), 151-160, 2010 | 68 | 2010 |
| Intra-CSF AAV9 and AAVrh10 administration in nonhuman primates: promising routes and vectors for which neurological diseases? K Bey, J Deniaud, L Dubreil, B Joussemet, J Cristini, C Ciron, J Hordeaux, ... Molecular Therapy Methods & Clinical Development 17, 771-784, 2020 | 65 | 2020 |
| Postsurgical assessment and long-term safety of recombinant adeno-associated virus–mediated gene transfer into the retinas of dogs and primates G Le Meur, M Weber, Y Péréon, A Mendes-Madeira, D Nivard, ... Archives of Ophthalmology 123 (4), 500-506, 2005 | 56 | 2005 |
| Oral administration of doxycycline allows tight control of transgene expression: a key step towards gene therapy of retinal diseases K Stieger, A Mendes-Madeira, GL Meur, M Weber, JY Deschamps, ... Gene therapy 14 (23), 1668-1673, 2007 | 48 | 2007 |
