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Ka Yang
Ka Yang
Harvard Medical School
Verified email at hms.harvard.edu - Homepage
Title
Cited by
Cited by
Year
Development of the first small molecule histone deacetylase 6 (HDAC6) degraders
K Yang, Y Song, H Xie, H Wu, YT Wu, ED Leisten, W Tang
Bioorganic & medicinal chemistry letters 28 (14), 2493-2497, 2018
1662018
Development of multifunctional histone deacetylase 6 degraders with potent antimyeloma activity
H Wu, K Yang, Z Zhang, ED Leisten, Z Li, H Xie, J Liu, KA Smith, ...
Journal of medicinal chemistry 62 (15), 7042-7057, 2019
1402019
Proteomic landscape of Alzheimer’s Disease: novel insights into pathogenesis and biomarker discovery
B Bai, D Vanderwall, Y Li, X Wang, S Poudel, H Wang, KK Dey, PC Chen, ...
Molecular neurodegeneration 16 (1), 55, 2021
1122021
Development of selective histone deacetylase 6 (HDAC6) degraders recruiting von Hippel–Lindau (VHL) E3 ubiquitin ligase
K Yang, H Wu, Z Zhang, ED Leisten, X Nie, B Liu, Z Wen, J Zhang, ...
ACS Medicinal Chemistry Letters 11 (4), 575-581, 2020
882020
Chemical synthesis and biological application of modified oligonucleotides
DA Glazier, J Liao, BL Roberts, X Li, K Yang, CM Stevens, W Tang
Bioconjugate Chemistry 31 (5), 1213-1233, 2020
642020
A cell-based target engagement assay for the identification of cereblon E3 ubiquitin ligase ligands and their application in HDAC6 degraders
K Yang, Y Zhao, X Nie, H Wu, B Wang, CM Almodovar-Rivera, H Xie, ...
Cell chemical biology 27 (7), 866-876. e8, 2020
612020
Development of selective small molecule MDM2 degraders based on nutlin
B Wang, S Wu, J Liu, K Yang, H Xie, W Tang
European Journal of Medicinal Chemistry 176, 476-491, 2019
612019
Synthesis of carbazoles and carbazole-containing heterocycles via rhodium-catalyzed tandem carbonylative benzannulations
W Song, X Li, K Yang, X Zhao, DA Glazier, B Xi, W Tang
The Journal of Organic Chemistry 81 (7), 2930-2942, 2016
602016
Iridium‐Catalyzed Dynamic Kinetic Isomerization: Expedient Synthesis of Carbohydrates from Achmatowicz Rearrangement Products
HY Wang, K Yang, SR Bennett, S Guo, W Tang
Angewandte Chemie International Edition 54 (30), 8756-8759, 2015
582015
Chiral Catalyst-Directed Dynamic Kinetic Diastereoselective Acylation of Lactols for De Novo Synthesis of Carbohydrate
HY Wang, K Yang, D Yin, C Liu, DA Glazier, W Tang
Organic letters 17 (21), 5272-5275, 2015
472015
Finding the sweet spot in ERLIC mobile phase for simultaneous enrichment of N-glyco and phosphopeptides
Y Cui, K Yang, DN Tabang, J Huang, W Tang, L Li
Journal of the American Society for Mass Spectrometry 30 (12), 2491-2501, 2019
252019
A total synthesis of (±)-rhododaurichromanic acid A via an oxa-[3+ 3] annulation of resorcinols
GY Luo, H Wu, Y Tang, H Li, HS Yeom, K Yang, RP Hsung
Synthesis, 2713-2720, 2015
222015
Synthesis of substituted tropones by sequential Rh-catalyzed [5+ 2] cycloaddition and elimination
W Song, B Xi, K Yang, W Tang
Tetrahedron 71 (35), 5979-5984, 2015
142015
Discovery of 2, 3′-diindolylmethanes as a novel class of PCSK9 modulators
GN Winston-McPherson, H Xie, K Yang, X Li, D Shu, W Tang
Bioorganic & medicinal chemistry letters 29 (16), 2345-2348, 2019
82019
JUMPt: comprehensive protein turnover modeling of in vivo pulse SILAC data by ordinary differential equations
SR Chepyala, X Liu, K Yang, Z Wu, AM Breuer, JH Cho, Y Li, A Mancieri, ...
Analytical chemistry 93 (40), 13495-13504, 2021
72021
A carbohydrate based chiron approach to the lactone intermediate employed in the synthesis of BC-ring fragment of (+)-spirastrellolide A
CC Wang, Y Tang, K Yang, XY Li, YB Wu, RP Hsung
Tetrahedron 69 (38), 8284-8290, 2013
72013
Accelerating multiplexed profiling of protein-ligand interactions: High-throughput plate-based reactive cysteine profiling with minimal input
K Yang, RL Whitehouse, SL Dawson, L Zhang, JG Martin, DS Johnson, ...
Cell Chemical Biology 31 (3), 565-576. e4, 2024
62024
From methylene bridged diindole to carbonyl linked benzimidazoleindole: Development of potent and metabolically stable PCSK9 modulators
H Xie, K Yang, GN Winston-McPherson, DS Stapleton, MP Keller, AD Attie, ...
European journal of medicinal chemistry 206, 112678, 2020
62020
Evaluation of a pooling chemoproteomics strategy with an FDA-approved drug library
H Sun, K Yang, X Zhang, Y Fu, J Yarbro, Z Wu, PC Chen, T Chen, J Peng
Biochemistry 62 (3), 624-632, 2022
42022
Synthesis and biological evaluation of FICZ analogues as agonists of aryl hydrocarbon receptor
H Wu, B Liu, K Yang, GN Winston-McPherson, ED Leisten, CM Vezina, ...
Bioorganic & medicinal chemistry letters 30 (5), 126959, 2020
42020
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