Stress and circulating cell-free mitochondrial DNA: A systematic review of human studies, physiological considerations, and technical recommendations C Trumpff, J Michelson, CJ Lagranha, V Taleon, KR Karan, G Sturm, ... Mitochondrion 59, 225-245, 2021 | 89 | 2021 |
Mitochondrial phenotypes in purified human immune cell subtypes and cell mixtures S Rausser, C Trumpff, MA McGill, A Junker, W Wang, SH Ho, A Mitchell, ... Elife 10, e70899, 2021 | 64 | 2021 |
OxPhos defects cause hypermetabolism and reduce lifespan in cells and in patients with mitochondrial diseases G Sturm, KR Karan, AS Monzel, B Santhanam, T Taivassalo, C Bris, ... Communications biology 6 (1), 22, 2023 | 37 | 2023 |
Mitochondrial respiratory capacity modulates LPS-induced inflammatory signatures in human blood KR Karan, C Trumpff, MA McGill, JE Thomas, G Sturm, V Lauriola, ... Brain, Behavior, & Immunity-Health 5, 100080, 2020 | 24 | 2020 |
A multi-omics longitudinal aging dataset in primary human fibroblasts with mitochondrial perturbations G Sturm, AS Monzel, KR Karan, J Michelson, SA Ware, A Cardenas, J Lin, ... Scientific Data 9 (1), 751, 2022 | 23 | 2022 |
Rare SLC1A1 variants in hot water epilepsy KR Karan, P Satishchandra, S Sinha, A Anand Human Genetics 136 (6), 693-703, 2017 | 17 | 2017 |
Cellular allostatic load is linked to increased energy expenditure and accelerated biological aging N Bobba-Alves, G Sturm, J Lin, SA Ware, KR Karan, AS Monzel, C Bris, ... Psychoneuroendocrinology 155, 106322, 2023 | 16 | 2023 |
Mitochondria in epithelial ovarian carcinoma exhibit abnormal phenotypes and blunted associations with biobehavioral factors S Bindra, MA McGill, MK Triplett, A Tyagi, PH Thaker, L Dahmoush, ... Scientific reports 11 (1), 11595, 2021 | 15 | 2021 |
Dynamic behavior of cell-free mitochondrial DNA in human saliva C Trumpff, S Rausser, R Haahr, KR Karan, G Gouspillou, E Puterman, ... Psychoneuroendocrinology 143, 105852, 2022 | 12 | 2022 |
Complete Mitochondrial Genome Analysis and Clinical Documentation of a Five‐Generational Indian Family with Mitochondrial 1555A> G Mutation and Postlingual Hearing Loss M Subathra, M Selvakumari, A Ramesh, R Ramakrishnan, KR Karan, ... Annals of Human Genetics 78 (3), 217-234, 2014 | 11 | 2014 |
Chronic glucocorticoid stress reveals increased energy expenditure and accelerated aging as cellular features of allostatic load N Bobba-Alves, G Sturm, J Lin, SA Ware, KR Karan, A Monzel, C Bris, ... bioRxiv, 2022.02. 22.481548, 2022 | 10 | 2022 |
OxPhos dysfunction causes hypermetabolism and reduces lifespan in cells and in patients with mitochondrial diseases G Sturm, KR Karan, A Monzel, BS Santhanam, T Taivassalo, C Bris, ... bioRxiv, 2021.11. 29.470428, 2021 | 10 | 2021 |
A genetic locus for sensory epilepsy precipitated by contact with hot water maps to chromosome 9p24. 3-p23 KR Karan, P Satishchandra, S Sinha, A Anand Journal of genetics 97, 391-398, 2018 | 8 | 2018 |
Leukocyte cytokine responses in adult patients with mitochondrial DNA defects KR Karan, C Trumpff, M Cross, KM Engelstad, AL Marsland, PJ McGuire, ... Journal of Molecular Medicine 100 (6), 963-971, 2022 | 7 | 2022 |
Mitochondrial profiling reveals dynamic, sex-and age-specific mitochondrial phenotypes in human immune cell subtypes S Rausser, C Trumpff, MA McGill, A Junker, W Wang, S Ho, A Mitchell, ... bioRxiv, 2020.10. 16.342923, 2020 | 3 | 2020 |
Somatic nuclear mitochondrial DNA insertions are prevalent in the human brain and accumulate over time in fibroblasts W Zhou, KR Karan, W Gu, HU Klein, G Sturm, PL De Jager, DA Bennett, ... bioRxiv, 2023 | 1 | 2023 |
Hot Water Epilepsy AR Torres, M Aquino-Cabrera, M Mohanty Journal of Pediatric Epilepsy 8 (04), 100-102, 2019 | 1 | 2019 |
Corrigendum to “Dynamic behavior of cell-free mitochondrial DNA in human saliva”[Psychoneuroendocrinology 143 (2022) 105852] C Trumpff, S Rausser, R Haahr, KR Karan, G Gouspillou, E Puterman, ... Psychoneuroendocrinology 144, 105884, 2022 | | 2022 |
CHRONIC GLUCOCORTICOID STRESS INCREASES ENERGY EXPENDITURE AND ACCELERATES AGING TRAJECTORIES IN HUMAN FIBROBLASTS N Bobba-Alves, G Sturm, J Lin, KR Karan, A Monzel, A Higgins-Chen, ... PSYCHOSOMATIC MEDICINE 84 (5), A112-A112, 2022 | | 2022 |
Mitochondrial respiratory capacity regulates acute LPS-stimulated inflammatory signatures in human blood KR Karan, C Trumpff, MA McGill, JE Thomas, G Sturm, V Lauriola, ... Psychoneuroendocrinology 107, 11, 2019 | | 2019 |