Abnormal bundling and accumulation of F-actin mediates tau-induced neuronal degeneration in vivo TA Fulga, I Elson-Schwab, V Khurana, ML Steinhilb, TL Spires, BT Hyman, ... Nature cell biology 9 (2), 139-148, 2007 | 508 | 2007 |
TOR-mediated cell-cycle activation causes neurodegeneration in a Drosophila tauopathy model V Khurana, Y Lu, ML Steinhilb, S Oldham, JM Shulman, MB Feany Current Biology 16 (3), 230-241, 2006 | 301 | 2006 |
Tau phosphorylation sites work in concert to promote neurotoxicity in vivo ML Steinhilb, D Dias-Santagata, TA Fulga, DL Felch, MB Feany Molecular biology of the cell 18 (12), 5060-5068, 2007 | 208 | 2007 |
S/P and T/P phosphorylation is critical for tau neurotoxicity in Drosophila ML Steinhilb, D Dias‐Santagata, EE Mulkearns, JM Shulman, J Biernat, ... Journal of neuroscience research 85 (6), 1271-1278, 2007 | 126 | 2007 |
The protease inhibitor, MG132, blocks maturation of the amyloid precursor protein Swedish mutant preventing cleavage by β-secretase ML Steinhilb, RS Turner, JR Gaut Journal of Biological Chemistry 276 (6), 4476-4484, 2001 | 91 | 2001 |
X11α modulates secretory and endocytic trafficking and metabolism of amyloid precursor protein: mutational analysis of the YENPTY sequence GD King, RG Perez, ML Steinhilb, JR Gaut, RS Turner Neuroscience 120 (1), 143-154, 2003 | 70 | 2003 |
Stable β-secretase activity and presynaptic cholinergic markers during progressive central nervous system amyloidogenesis in Tg2576 mice JT Gau, ML Steinhilb, TC Kao, CJ D'Amato, JR Gaut, KA Frey, RS Turner The American journal of pathology 160 (2), 731-738, 2002 | 69 | 2002 |
Synergistic effects of Munc18a and X11 proteins on amyloid precursor protein metabolism CS Ho, V Marinescu, ML Steinhilb, JR Gaut, RS Turner, EL Stuenkel Journal of Biological Chemistry 277 (30), 27021-27028, 2002 | 66 | 2002 |
Implicating calpain in tau-mediated toxicity in vivo JB Reinecke, SL DeVos, JP McGrath, AM Shepard, DK Goncharoff, ... PLoS One 6 (8), e23865, 2011 | 60 | 2011 |
ELISA analysis of β‐secretase cleavage of the Swedish amyloid precursor protein in the secretory and endocytic pathways ML Steinhilb, RS Turner, JR Gaut Journal of neurochemistry 80 (6), 1019-1028, 2002 | 40 | 2002 |
Animal models of neurodegenerative disease: Recent advances in fly highlight innovative approaches to drug discovery JA Tello, HE Williams, RM Eppler, ML Steinhilb, M Khanna Frontiers in molecular neuroscience 15, 883358, 2022 | 24 | 2022 |
Preparation of prokaryotic and eukaryotic organisms using chemical drying for morphological analysis in scanning electron microscopy (SEM) MA Koon, KA Ali, RM Speaker, JP McGrath, EW Linton, ML Steinhilb JoVE (Journal of Visualized Experiments), e58761, 2019 | 15 | 2019 |
The Drosophila model system to study tau action MB Trotter, TD Stephens, JP McGrath, ML Steinhilb Methods in Cell Biology 141, 259-286, 2017 | 15 | 2017 |
Stable beta-secretase activity and presynaptic cholinergic markers during progressive CNS amyloidogenesis in Tg2576 mice JT Gau, M Steinhilb, J Gaut, K Frey, RS Turner, TC Kao, C D'Amato NEUROBIOLOGY OF AGING 23 (1), S250-S250, 2002 | 1 | 2002 |
X11 alpha/mint-1 inhibits gamma-but not beta-secretase cleavage of amyloid precursor protein G King, M Steinhilb, RG Perez, J Gaut, RS Turner NEUROBIOLOGY OF AGING 23 (1), S185-S185, 2002 | 1 | 2002 |
Quantitative evaluation of β-secretase cleavage of amyloid precursor protein in the secretory and endocytic pathways ML Steinhilb, RS Turner, JR Gaut Neurobiology of Aging, 115, 2000 | 1 | 2000 |
A Novel Tauopathy Model Utilizing Dictyostelium discoideum KE Miller, AL Erwin, SL Hall, ML Steinhilb, CK Damer MOLECULAR BIOLOGY OF THE CELL 23, 2012 | | 2012 |
Cytoplasmic proteins that interact with carboxyl-terminus of amyloid precursor protein alter metabolism, beta-secretase cleavage and A beta production M Steinhilb, G King, S Turner, J Gaut NEUROBIOLOGY OF AGING 23 (1), S202-S202, 2002 | | 2002 |
Cellular trafficking and metabolism of the Alzheimer's disease amyloid precursor protein (APP) in the secretory and endocytic pathways ML Steinhilb University of Michigan, 2002 | | 2002 |
PROTEIN SYNTHESIS, POST-TRANSLATION MODIFICATION, AND DEGRADATION-The protease inhibitor, MG132, blocks maturation of the amyloid precursor protein Swedish mutant preventing … ML Steinhilb, RS Turner, JR Gaut Journal of Biological Chemistry 276 (6), 4476-4484, 2001 | | 2001 |