| Natural alkaloids as P-gp inhibitors for multidrug resistance reversal in cancer P Joshi, RA Vishwakarma, SB Bharate European Journal of Medicinal Chemistry 138, 273-292, 2017 | 151 | 2017 |
| Discovery of a marine-derived bis-indole alkaloid fascaplysin, as a new class of potent P-glycoprotein inducer and establishment of its structure–activity relationship S Manda, S Sharma, A Wani, P Joshi, V Kumar, SK Guru, SS Bharate, ... European journal of medicinal chemistry 107, 1-11, 2016 | 76 | 2016 |
| Boeravinone B, A Novel Dual Inhibitor of NorA Bacterial Efflux Pump of Staphylococcus aureus and Human P-Glycoprotein, Reduces the Biofilm Formation and Intracellular Invasion … S Singh, NP Kalia, P Joshi, A Kumar, PR Sharma, A Kumar, SB Bharate, ... Frontiers in microbiology 8, 1868, 2017 | 72 | 2017 |
| Total synthesis and anti-cholinesterase activity of marine-derived bis-indole alkaloid fascaplysin SB Bharate, S Manda, P Joshi, B Singh, RA Vishwakarma MedChemComm 3 (9), 1098-1103, 2012 | 67 | 2012 |
| Osthol and curcumin as inhibitors of human Pgp and multidrug efflux pumps of Staphylococcus aureus: Reversing the resistance against frontline antibacterial drugs. P Joshi, S Singh, A Wani, S Sharma, SK Jain, B Singh, B Gupta, N Satti, ... Med. Chem. Commun. 5, 1540-1547, 2014 | 55 | 2014 |
| Synthesis and biological evaluation of pyrrole-based chalcones as CYP1 enzyme inhibitors, for possible prevention of cancer and overcoming cisplatin resistance IS Williams, P Joshi, L Gatchie, M Sharma, NK Satti, RA Vishwakarma, ... Bioorganic & Medicinal Chemistry Letters 27 (16), 3683-3687, 2017 | 48 | 2017 |
| Discovery and characterization of novel CYP1B1 inhibitors based on heterocyclic chalcones: Overcoming cisplatin resistance in CYP1B1-overexpressing lines NJ Horley, KJM Beresford, T Chawla, GJP McCann, KC Ruparelia, ... European Journal of Medicinal Chemistry 129, 159-174, 2017 | 46 | 2017 |
| Meridianin derivatives as potent Dyrk1A inhibitors and neuroprotective agents RR Yadav, S Sharma, P Joshi, A Wani, RA Vishwakarma, A Kumar, ... Bioorganic & medicinal chemistry letters 25 (15), 2948-2952, 2015 | 45 | 2015 |
| Quinazoline derivatives as selective CYP1B1 inhibitors MUM Siddique, GJP McCann, VR Sonawane, N Horley, L Gatchie, ... European Journal of Medicinal Chemistry 130, 320-327, 2017 | 43 | 2017 |
| Colchicine derivatives with potent anticancer activity and reduced P-glycoprotein induction liability B Singh, A Kumar, P Joshi, SK Guru, S Kumar, ZA Wani, G Mahajan, ... Organic & biomolecular chemistry 13 (20), 5674-5689, 2015 | 43 | 2015 |
| Chromatography-free isolation of rohitukine from leaves of Dysoxylum binectariferum: Evaluation for in-vitro cytotoxicity, Cdk inhibition and physicochemical properties. RAV Vikas Kumar, Santosh K. Guru, Shreyans K. Jain, Prashant Joshi, Sumit G ... Bioorg. Med. Chem. Lett. 26, 3457-3463, 2016 | 42 | 2016 |
| Pyrano-isochromanones as IL-6 inhibitors: Synthesis, in-vitro and in-vivo anti-arthritic activity. J S.K., S Singh, A Khajuria, SK Guru, P Joshi, S Meena, J Nadkarni, ... J. Med. Chem. 57, 7085-7097, 2014 | 42 | 2014 |
| Identification of Potent and Selective CYP1A1 Inhibitors via Combined Ligand and Structure-Based Virtual Screening and Their in Vitro Validation in Sacchrosomes and Live Human … P Joshi, GJP McCann, VR Sonawane, RA Vishwakarma, B Chaudhuri, ... Journal of chemical information and modeling 57 (6), 1309-1320, 2017 | 41 | 2017 |
| 6-Aryl substituted 4-(4-cyanomethyl) phenylamino quinazolines as a new class of isoform-selective PI3K-alpha inhibitors RR Yadav, SK Guru, P Joshi, G Mahajan, MJ Mintoo, V Kumar, ... European Journal of Medicinal Chemistry 122, 731-743, 2016 | 41 | 2016 |
| Biphenyl-4-carboxylic acid [2-(1H-indol-3-yl)-ethyl]-methylamide (CA224), a non-planar analog of fascaplysin inhibits Cdk4 and tubulin polymerization: Evaluation of in vitro … S Mahale, SB Bharate, S * Manda, P Joshi, SS Bharate, PR Jenkins, ... J. Med. Chem. 57, 9658–9672, 2014 | 39 | 2014 |
| Anti-tumour Potential of BPT: A Dual Inhibitor of Cdk4 and Tubulin Polymerization S Mahale, SB Bharate, S Manda, P Joshi, P Jenkins, RA Vishwakarma, ... Cell Death Dis. 6, e1743, 2015 | 38 | 2015 |
| Discovery of 4-acetyl-3-(4-fluorophenyl)-1-(p-tolyl)-5-methylpyrrole as a dual inhibitor of human P-glycoprotein and Staphylococcus aureus Nor A efflux pump JB Bharate, S Singh, A Wani, S Sharma, P Joshi, IA Khan, A Kumar, ... Organic & biomolecular chemistry 13 (19), 5424-5431, 2015 | 35 | 2015 |
| Identification of ZINC02765569: a potent inhibitor of PTP1B by vHTS P Joshi, GS Deora, V Rathore, O Tanwar, AK Rawat, AK Srivastava, ... Medicinal Chemistry Research 22 (1), 28-34, 2013 | 26 | 2013 |
| Biphenyl urea derivatives as selective CYP1B1 inhibitors MUM Siddique, GJP McCann, V Sonawane, N Horley, IS Williams, ... Organic & Biomolecular Chemistry 14 (38), 8931-8936, 2016 | 25 | 2016 |
| 3-(Benzo[d][1,3]dioxol-5-ylamino)-N-(4-fluorophenyl)thiophene-2- carboxamide overcomes cancer chemoresistance via inhibition of angiogenesis and P-glycoprotein efflux pump activity SBB Ramesh Mudududdla, Santosh K. Guru, Abubakar Wani Sadhana Sharma ... organic and biomolecular chemistry, 2015 | 23 | 2015 |
Ajay KumarSenior Technical Officer, PK-PD-Toxicology Division, Indian Institute of Integrative MedicineVerified email at iiim.res.in
