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Gene Hopping
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AChBP‐targeted α‐conotoxin correlates distinct binding orientations with nAChR subtype selectivity
S Dutertre, C Ulens, R Büttner, A Fish, R van Elk, Y Kendel, G Hopping, ...
The EMBO journal 26 (16), 3858-3867, 2007
1982007
Total synthesis of the analgesic conotoxin MrVIB through selenocysteine‐assisted folding
AD de Araujo, B Callaghan, ST Nevin, NL Daly, DJ Craik, M Moretta, ...
Angewandte Chemie International Edition 29 (50), 6527-6529, 2011
932011
Designed α-sheet peptides inhibit amyloid formation by targeting toxic oligomers
G Hopping, J Kellock, RP Barnwal, P Law, J Bryers, G Varani, B Caughey, ...
Elife 3, e01681, 2014
822014
α-Conotoxins PnIA and [A10L] PnIA stabilize different states of the α7-L247T nicotinic acetylcholine receptor
RC Hogg, G Hopping, PF Alewood, DJ Adams, D Bertrand
Journal of Biological Chemistry 278 (29), 26908-26914, 2003
722003
Peptides composed of alternating L-and D-amino acids inhibit amyloidogenesis in three distinct amyloid systems independent of sequence
J Kellock, G Hopping, B Caughey, V Daggett
Journal of molecular biology 428 (11), 2317-2328, 2016
602016
Nature versus design: the conformational propensities of d-amino acids and the importance of side chain chirality
CL Towse, G Hopping, I Vulovic, V Daggett
Protein Engineering, Design & Selection 27 (11), 447-455, 2014
432014
A potent peptide-steroid conjugate accumulates in cartilage and reverses arthritis without evidence of systemic corticosteroid exposure
ML Cook Sangar, EJ Girard, G Hopping, C Yin, F Pakiam, MY Brusniak, ...
Science translational medicine 12 (533), eaay1041, 2020
342020
Designed Trpzip-3 β-hairpin inhibits amyloid formation in two different amyloid systems
G Hopping, J Kellock, B Caughey, V Daggett
ACS Medicinal Chemistry Letters 4 (9), 824-828, 2013
312013
Hydrophobic residues at position 10 of α-conotoxin PnIA influence subtype selectivity between α7 and α3β2 neuronal nicotinic acetylcholine receptors
G Hopping, CIA Wang, RC Hogg, ST Nevin, RJ Lewis, DJ Adams, ...
Biochemical pharmacology 91 (4), 534-542, 2014
272014
Marine toxins as sources of drug leads
P Alewood, G Hopping, C Armishaw
Australian journal of chemistry 56 (8), 769-774, 2003
272003
A TfR-binding cystine-dense peptide promotes blood–brain barrier penetration of bioactive molecules
ZR Crook, E Girard, GP Sevilla, M Merrill, D Friend, PB Rupert, F Pakiam, ...
Journal of molecular biology 432 (14), 3989-4009, 2020
262020
Benzhydrylamine linker grafting: a strategy for the improved synthesis of C‐terminal peptide amides
D Alewood, G Hopping, A Brust, RC Reid, PF Alewood
Journal of Peptide Science 16 (10), 551-557, 2010
72010
Rapid Access to ω-Conotoxin Chimeras using Native Chemical Ligation
G Hopping, RJ Lewis, PF Alewood
Australian journal of chemistry 62 (10), 1333-1338, 2009
62009
Pacifastin-derived Peptides Target Tumors for Use in In Vivo Imaging
TL Sottero, EJ Girard, C Myers, G Hopping, AJ Mhyre, JM Olson
Anticancer Research 38 (1), 51-60, 2018
22018
Amyloidosis-inhibiting polypeptides and their use
V Daggett, G Hopping
22014
Hydrophobic residues at position 10 of a-conotoxin PnIA influence subtype selectivity between a7 and a3ß2 neuronal nicotinic acetylcholine receptors
G Hopping, CI Wang, R Hogg, S Nevin, R Lewis, DJ Adams, P Alewood
Biochemical Pharmacology 91 (4), 534-542, 2014
22014
Transferrin receptor targeting peptides
Z Crook, MY Brusniak, J Olson, AJ Mhyre, C Yin, GG Hopping, R Strong
US Patent App. 17/312,703, 2022
12022
Synthesis, Structure and Activity of Disulfide-Rich Conus Peptides
GG Hopping
12006
Conjugates of cartilage-homing peptides
GG Hopping, JA Simon, C Yin, C Mehlin, MLC SANGAR, AJ Mhyre, ...
US Patent App. 17/049,148, 2021
2021
Transferrin receptor targeting peptides
Z CROOK, M BRUSNIAK, J Olson, AJ MHYRE, C Yin, GG HOPPING, ...
2020
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