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Jen-Wei Huang
Jen-Wei Huang
Associate Research Scientist, Columbia University Medical Center
Verified email at cumc.columbia.edu
Title
Cited by
Cited by
Year
Restoration of replication fork stability in BRCA1-and BRCA2-deficient cells by inactivation of SNF2-family fork remodelers
A Taglialatela, S Alvarez, G Leuzzi, V Sannino, L Ranjha, JW Huang, ...
Molecular cell 68 (2), 414-430. e8, 2017
3402017
Replication fork slowing and reversal upon DNA damage require PCNA polyubiquitination and ZRANB3 DNA translocase activity
M Vujanovic, J Krietsch, MC Raso, N Terraneo, R Zellweger, JA Schmid, ...
Molecular cell 67 (5), 882-890. e5, 2017
2332017
MicroRNA-138 modulates DNA damage response by repressing histone H2AX expression
Y Wang, JW Huang, M Li, WK Cavenee, PS Mitchell, X Zhou, M Tewari, ...
Molecular Cancer Research 9 (8), 1100-1111, 2011
1692011
Functional interrogation of DNA damage response variants with base editing screens
R Cuella-Martin, SB Hayward, X Fan, X Chen, JW Huang, A Taglialatela, ...
Cell 184 (4), 1081-1097. e19, 2021
1632021
MiR-96 downregulates REV1 and RAD51 to promote cellular sensitivity to cisplatin and PARP inhibition
Y Wang, JW Huang, P Calses, CJ Kemp, T Taniguchi
Cancer research 72 (16), 4037-4046, 2012
1432012
Stimulation of CRISPR-mediated homology-directed repair by an engineered RAD18 variant
TS Nambiar, P Billon, G Diedenhofen, SB Hayward, A Taglialatela, K Cai, ...
Nature Communications 10 (1), 3395, 2019
1132019
Treacher Collins syndrome TCOF1 protein cooperates with NBS1 in the DNA damage response
A Ciccia, JW Huang, L Izhar, ME Sowa, JW Harper, SJ Elledge
Proceedings of the National Academy of Sciences 111 (52), 18631-18636, 2014
1102014
Systematic screen identifies miRNAs that target RAD51 and RAD51D to enhance chemosensitivity
JW Huang, Y Wang, KK Dhillon, P Calses, E Villegas, PS Mitchell, ...
Molecular cancer research 11 (12), 1564-1573, 2013
1102013
REV1-Polζ maintains the viability of homologous recombination-deficient cancer cells through mutagenic repair of PRIMPOL-dependent ssDNA gaps
A Taglialatela, G Leuzzi, V Sannino, R Cuella-Martin, JW Huang, ...
Molecular cell 81 (19), 4008-4025. e7, 2021
972021
FANCI regulates recruitment of the FA core complex at sites of DNA damage independently of FANCD2
M Castella, C Jacquemont, EL Thompson, JE Yeo, RS Cheung, ...
PLoS genetics 11 (10), e1005563, 2015
912015
p53 is positively regulated by miR-542-3p
Y Wang, JW Huang, M Castella, DG Huntsman, T Taniguchi
Cancer research 74 (12), 3218-3227, 2014
662014
DGCR8 mediates repair of UV-induced DNA damage independently of RNA processing
PC Calses, KK Dhillon, N Tucker, Y Chi, J Huang, M Kawasumi, ...
Cell reports 19 (1), 162-174, 2017
382017
MCM8IP activates the MCM8-9 helicase to promote DNA synthesis and homologous recombination upon DNA damage
JW Huang, A Acharya, A Taglialatela, TS Nambiar, R Cuella-Martin, ...
Nature communications 11 (1), 2948, 2020
342020
Time for remodeling: SNF2-family DNA translocases in replication fork metabolism and human disease
SA Joseph, A Taglialatela, G Leuzzi, JW Huang, R Cuella-Martin, A Ciccia
DNA repair 95, 102943, 2020
252020
The synthesis and proteasomal degradation of a model substrate Ub5DHFR
YA Lam, JW Huang, O Showole
Methods in enzymology 398, 379-390, 2005
142005
SMARCAL1 is a dual regulator of innate immune signaling and PD-L1 expression that promotes tumor immune evasion
G Leuzzi, A Vasciaveo, A Taglialatela, X Chen, TM Firestone, ...
Cell 187 (4), 861-881. e32, 2024
22024
Mechanism of DNA unwinding by hexameric MCM8–9 in complex with HROB
A Acharya, H Bret, JW Huang, M Muetze, M Goese, V Kissling, R Seidel, ...
Research Square, 2023
12023
MicroRNA-103 and 107 target RAD51 and RAD51D to regulate homologous recombination and enhance cellular sensitivity to DNA damaging agents
JW Huang
12013
MicroRNA-mediated regulation of the Fanconi anemia-BRCA pathway
JW Huang, E Villegas, T Taniguchi
Cancer Research 70 (8_Supplement), 1951-1951, 2010
12010
Abstract PR009: SMARCAL1 is a dual regulator of innate immune signaling and PD-L1 expression that promotes tumor immune evasion
G Leuzzi, A Vasciaveo, A Taglialatela, X Chen, TM Firestone, ...
Cancer Research 84 (1_Supplement), PR009-PR009, 2024
2024
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