Traditional Chinese medicine compounds regulate autophagy for treating neurodegenerative disease: a mechanism review ZY Wang, J Liu, Z Zhu, CF Su, SG Sreenivasmurthy, A Iyaswamy, JH Lu, ... Biomedicine & Pharmacotherapy 133, 110968, 2021 | 61 | 2021 |
Celastrol enhances transcription factor EB (TFEB)-mediated autophagy and mitigates Tau pathology: Implications for Alzheimer's disease therapy C Yang, C Su, A Iyaswamy, SK Krishnamoorthi, Z Zhu, S Yang, BC Tong, ... Acta Pharmaceutica Sinica B 12 (4), 1707-1722, 2022 | 60 | 2022 |
A curcumin derivative activates TFEB and protects against parkinsonian neurotoxicity in vitro Z Wang, C Yang, J Liu, B Chun-Kit Tong, Z Zhu, S Malampati, ... International journal of molecular sciences 21 (4), 1515, 2020 | 47 | 2020 |
Theranostic F-SLOH mitigates Alzheimer's disease pathology involving TFEB and ameliorates cognitive functions in Alzheimer's disease models A Iyaswamy, X Wang, S Krishnamoorthi, V Kaliamoorthy, ... Redox biology 51, 102280, 2022 | 43 | 2022 |
Targeting aggrephagy for the treatment of Alzheimer’s disease S Malampati, JX Song, B Chun-Kit Tong, A Nalluri, CB Yang, Z Wang, ... Cells 9 (2), 311, 2020 | 43 | 2020 |
Resveratrol in rodent models of Parkinson’s disease: A systematic review of experimental studies CF Su, L Jiang, XW Zhang, A Iyaswamy, M Li Frontiers in Pharmacology 12, 644219, 2021 | 42 | 2021 |
Antidiabetic activity and potential mechanism of amentoflavone in diabetic mice C Su, C Yang, M Gong, Y Ke, P Yuan, X Wang, M Li, X Zheng, W Feng Molecules 24 (11), 2184, 2019 | 42 | 2019 |
Antihyperlipidaemic and antioxidant effect of the total flavonoids in Selaginella tamariscina (Beauv.) Spring in diabetic mice X Zheng, W Wang, L Zhang, C Su, Y Wu, Y Ke, Q Hou, Z Liu, A Gao, ... Journal of Pharmacy and Pharmacology 65 (5), 757-766, 2013 | 42 | 2013 |
Qingyangshen mitigates amyloid-β and Tau aggregate defects involving PPARα-TFEB activation in transgenic mice of Alzheimer's disease A Iyaswamy, SK Krishnamoorthi, H Zhang, SG Sreenivasmurthy, Z Zhu, ... Phytomedicine 91, 153648, 2021 | 37 | 2021 |
Protopine promotes the proteasomal degradation of pathological tau in Alzheimer's disease models via HDAC6 inhibition SG Sreenivasmurthy, A Iyaswamy, S Krishnamoorthi, S Senapati, ... Phytomedicine 96, 153887, 2022 | 34 | 2022 |
Lignanamides with potent antihyperlipidemic activities from the root bark of Lycium chinense H Chen, YJ Li, YJ Sun, JH Gong, K Du, YL Zhang, CF Su, QQ Han, ... Fitoterapia 122, 119-125, 2017 | 34 | 2017 |
Lysosomal TPCN (two pore segment channel) inhibition ameliorates beta-amyloid pathology and mitigates memory impairment in Alzheimer disease BCK Tong, AJ Wu, AS Huang, R Dong, S Malampati, A Iyaswamy, ... Autophagy 18 (3), 624-642, 2022 | 33 | 2022 |
Bromo-protopine, a novel protopine derivative, alleviates tau pathology by activating chaperone-mediated autophagy for Alzheimer’s disease therapy SG Sreenivasmurthy, A Iyaswamy, S Krishnamoorthi, RN Reddi, ... Frontiers in Molecular Biosciences 9, 1030534, 2022 | 23 | 2022 |
Tetrandrine ameliorates cognitive deficits and mitigates tau aggregation in cell and animal models of tauopathies BCK Tong, AS Huang, AJ Wu, A Iyaswamy, OKY Ho, AHY Kong, ... Journal of Biomedical Science 29 (1), 85, 2022 | 23 | 2022 |
Corynoxine B derivative CB6 prevents Parkinsonian toxicity in mice by inducing PIK3C3 complex-dependent autophagy Z Zhu, L Liu, C Su, J Liu, BCK Tong, A Iyaswamy, S Krishnamoorthi, ... Acta Pharmacologica Sinica 43 (10), 2511-2526, 2022 | 23 | 2022 |
Mechanism by which Eucommia ulmoides leaves Regulate Nonalcoholic fatty liver disease based on system pharmacology M Gong, C Su, M Fan, P Wang, B Cui, Z Guo, S Liang, L Yang, X Liu, ... Journal of Ethnopharmacology 282, 114603, 2022 | 23 | 2022 |
Klotho an autophagy stimulator as a potential therapeutic target for Alzheimer’s disease: A review TY Fung, A Iyaswamy, SG Sreenivasmurthy, S Krishnamoorthi, XJ Guan, ... Biomedicines 10 (3), 705, 2022 | 22 | 2022 |
TFEB, a master regulator of autophagy and biogenesis, unexpectedly promotes apoptosis in response to the cyclopentenone prostaglandin 15d-PGJ2 C Yang, J Liu, BCK Tong, Z Wang, Z Zhu, C Su, SG Sreenivasmurthy, ... Acta Pharmacologica Sinica 43 (5), 1251-1263, 2022 | 19 | 2022 |
Trilateral association of autophagy, mTOR and Alzheimer’s disease: potential pathway in the development for Alzheimer’s disease therapy A Subramanian, T Tamilanban, A Alsayari, G Ramachawolran, LS Wong, ... Frontiers in Pharmacology 13, 1094351, 2022 | 18 | 2022 |
Construction of Cd(II) complexes based on 2-(1H-imidazol-1-methyl)-1H-benzimidazole and 1,4-benzenedicarboxylate YQ Yang, CF Su, JD Zhang, HX Yang, GY Zhang, XR Meng Journal of Coordination Chemistry 69 (24), 3762-3775, 2016 | 16 | 2016 |