Devarajan Karunagaran
Devarajan Karunagaran
Emeritus Professor, Bhupat and Jyoti Mehta School of Biosciences, Department of Biotechnology
Verified email at - Homepage
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A hierarchical network of interreceptor interactions determines signal transduction by Neu differentiation factor/neuregulin and epidermal growth factor.
E Tzahar, H Waterman, X Chen, G Levkowitz, D Karunagaran, S Lavi, ...
Molecular and Cellular Biology 16, 5276-5287, 1996
ErbB-2 is a common auxiliary subunit of NDF and EGF receptors: implications for breast cancer.
D Karunagaran, E Tzahar, RR Beerli, X Chen, D Graus-Porta, BJ Ratzkin, ...
The EMBO journal 15, 254-264, 1996
The flavonoid quercetin induces cell cycle arrest and mitochondria-mediated apoptosis in human cervical cancer (HeLa) cells through p53 induction and NF-κB inhibition
R Vidya Priyadarsini, R Senthil Murugan, S Maitreyi, K Ramalingam, ...
European journal of pharmacology 649, 84-91, 2010
Allicin (from garlic) induces caspase-mediated apoptosis in cancer cells
S Oommen, RJ Anto, G Srinivas, D Karunagaran
European journal of pharmacology 485 (1-3), 97-103, 2004
ErbB-3 and ErbB-4 function as the respective low and high affinity receptors of all Neu differentiation factor/heregulin isoforms.
E Tzahar, G Levkowitz, D Karunagaran, L Yi, E Peles, S Lavi, D Chang, ...
Journal of Biological Chemistry 269, 25226-25233, 1994
Induction of apoptosis by curcumin and its implications for cancer therapy
D Karunagaran, R Rashmi, TR Kumar
Curr Cancer Drug Targets 5, 117-129, 2005
Structural and functional aspects of the multiplicity of Neu differentiation factors.
D Wen, SV Suggs, D Karunagaran, N Liu, RL Cupples, Y Luo, ...
Molecular and cellular biology 14, 1909-1919, 1994
Sensitization of taxol-induced apoptosis by curcumin involves down-regulation of nuclear factor-κB and the serine/threonine kinase Akt and is independent of tubulin polymerization
VB Smitha, TP Vinesh Kumar, A Deepti, A Nair, D Karunagaran, RJ Anto
Journal of Biological Chemistry 280, 6301-6308, 2005
Emodin induces apoptosis of human cervical cancer cells through poly (ADP-ribose) polymerase cleavage and activation of caspase-9
G Srinivas, RJ Anto, P Srinivas, S Vidhyalakshmi, VP Senan, ...
European journal of pharmacology 473, 117-125, 2003
NF-κB is constitutively activated in high-grade squamous intraepithelial lesions and squamous cell carcinomas of the human uterine cervix
A Nair, M Venkatraman, TT Maliekal, B Nair, D Karunagaran
Oncogene 22, 50-58, 2003
Advances in chalcones with anticancer activities
C Karthikeyan, N SH Narayana Moorthy, S Ramasamy, U Vanam, ...
Recent patents on anti-cancer drug discovery 10 (1), 97-115, 2015
An immunological approach reveals biological differences between the two NDF/heregulin receptors, ErbB-3 and ErbB-4
X Chen, G Levkowitz, E Tzahar, D Karunagaran, S Lavi, N Ben-Baruch, ...
Journal of Biological Chemistry 271, 7620-7629, 1996
Inhibition of nuclear factor-κB activity is involved in E1A-mediated sensitization of radiation-induced apoptosis
R Shao, D Karunagaran, BP Zhou, K Li, SS Lo, J Deng, P Chiao, ...
Journal of Biological Chemistry 272, 32739-32742, 1997
The neem limonoids azadirachtin and nimbolide induce cell cycle arrest and mitochondria-mediated apoptosis in human cervical cancer (HeLa) cells
RV Priyadarsini, RS Murugan, P Sripriya, D Karunagaran, S Nagini
Free radical research 44, 624-634, 2010
Human colon cancer cells differ in their sensitivity to curcumin-induced apoptosis and heat shock protects them by inhibiting the release of apoptosis-inducing factor and caspases
R Rashmi, TR Santhosh Kumar, D Karunagaran
FEBS letters 538, 19-24, 2003
Biological and chemical inhibitors of NF‐κB sensitize SiHa cells to cisplatin‐induced apoptosis
M Venkatraman, RJ Anto, A Nair, M Varghese, D Karunagaran
Molecular carcinogenesis 44, 51-59, 2005
Chlorophyll Revisited: Anti-inflammatory Activities of Chlorophyll a and Inhibition of Expression of TNF-α Gene by the Same
A Subramoniam, VV Asha, SA Nair, SP Sasidharan, PK Sureshkumar, ...
Inflammation 35, 959-966, 2012
Human colon cancer cells lacking Bax resist curcumin-induced apoptosis and Bax requirement is dispensable with ectopic expression of Smac or downregulation of Bcl-XL
R Rashmi, S Kumar, D Karunagaran
Carcinogenesis 26, 713-723, 2005
Curcumin and emodin down-regulate TGF-β signaling pathway in human cervical cancer cells
PC Thacker, D Karunagaran
PloS one 10 (3), e0120045, 2015
Ectopic expression of Hsp70 confers resistance and silencing its expression sensitizes human colon cancer cells to curcumin-induced apoptosis
R Rashmi, S Kumar, D Karunagaran
Carcinogenesis 25, 179-187, 2004
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