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Rolf Brekken
Rolf Brekken
Verified email at utsouthwestern.edu - Homepage
Title
Cited by
Cited by
Year
Matrix metalloproteinase-9 triggers the angiogenic switch during carcinogenesis
G Bergers, R Brekken, G McMahon, TH Vu, T Itoh, K Tamaki, K Tanzawa, ...
Nature cell biology 2 (10), 737-744, 2000
34452000
Hypoxia-inducible factor 1α induces fibrosis and insulin resistance in white adipose tissue
N Halberg, T Khan, ME Trujillo, I Wernstedt-Asterholm, AD Attie, ...
Molecular and cellular biology, 2009
10142009
SPARC, a matricellular protein: at the crossroads of cell–matrix
RA Brekken, EH Sage
Matrix Biology 19 (7), 569-580, 2000
10102000
Phosphatidylserine is a global immunosuppressive signal in efferocytosis, infectious disease, and cancer
RB Birge, S Boeltz, S Kumar, J Carlson, J Wanderley, D Calianese, ...
Cell Death & Differentiation 23 (6), 962-978, 2016
5972016
Pancreatic cancer stroma: an update on therapeutic targeting strategies
AN Hosein, RA Brekken, A Maitra
Nature reviews Gastroenterology & hepatology 17 (8), 487-505, 2020
5462020
Selective inhibition of vascular endothelial growth factor (VEGF) receptor 2 (KDR/Flk-1) activity by a monoclonal anti-VEGF antibody blocks tumor growth in mice
RA Brekken, JP Overholser, VA Stastny, J Waltenberger, JD Minna, ...
Cancer research 60 (18), 5117-5124, 2000
5032000
Role of VEGF-A in vascularization of pancreatic islets
E Lammert, G Gu, M McLaughlin, D Brown, R Brekken, LC Murtaugh, ...
Current Biology 13 (12), 1070-1074, 2003
4752003
Dichotomous effects of VEGF-A on adipose tissue dysfunction
K Sun, IW Asterholm, CM Kusminski, AC Bueno, ZV Wang, JW Pollard, ...
Proceedings of the national academy of sciences 109 (15), 5874-5879, 2012
4742012
Antibody compositions for selectively inhibiting VEGF
PE Thorpe, RA Brekken
US Patent 6,342,219, 2002
4672002
Alternatively spliced vascular endothelial growth factor receptor-2 is an essential endogenous inhibitor of lymphatic vessel growth
RJC Albuquerque, T Hayashi, WG Cho, ME Kleinman, S Dridi, A Takeda, ...
Nature medicine 15 (9), 1023-1030, 2009
4482009
Soluble Eph A receptors inhibit tumor angiogenesis and progression in vivo
DM Brantley, N Cheng, EJ Thompson, Q Lin, RA Brekken, PE Thorpe, ...
Oncogene 21 (46), 7011-7026, 2002
4092002
27-Hydroxycholesterol promotes cell-autonomous, ER-positive breast cancer growth
Q Wu, T Ishikawa, R Sirianni, H Tang, JG McDonald, IS Yuhanna, ...
Cell reports 5 (3), 637-645, 2013
3522013
Angiogenic role of LYVE-1–positive macrophages in adipose tissue
CH Cho, Y Jun Koh, J Han, HK Sung, H Jong Lee, T Morisada, ...
Circulation research 100 (4), e47-e57, 2007
3272007
Monitoring response to anticancer therapy by targeting microbubbles to tumor vasculature
G Korpanty, JG Carbon, PA Grayburn, JB Fleming, RA Brekken
Clinical Cancer Research 13 (1), 323-330, 2007
3242007
A small molecule modulates Jumonji histone demethylase activity and selectively inhibits cancer growth
L Wang, J Chang, D Varghese, M Dellinger, S Kumar, AM Best, J Ruiz, ...
Nature communications 4 (1), 2035, 2013
3152013
Vascular endothelial growth factor promotes fibrosis resolution and repair in mice
L Yang, J Kwon, Y Popov, GB Gajdos, T Ordog, RA Brekken, ...
Gastroenterology 146 (5), 1339-1350. e1, 2014
2792014
A peptoid “antibody surrogate” that antagonizes VEGF receptor 2 activity
DG Udugamasooriya, SP Dineen, RA Brekken, T Kodadek
Journal of the American Chemical Society 130 (17), 5744-5752, 2008
2722008
Non-nuclear estrogen receptor α signaling promotes cardiovascular protection but not uterine or breast cancer growth in mice
KL Chambliss, Q Wu, S Oltmann, ES Konaniah, M Umetani, KS Korach, ...
The Journal of clinical investigation 120 (7), 2319-2330, 2010
2702010
Oncogene mutations, copy number gains and mutant allele specific imbalance (MASI) frequently occur together in tumor cells
J Soh, N Okumura, WW Lockwood, H Yamamoto, H Shigematsu, ...
PloS one 4 (10), e7464, 2009
2642009
TBK1 directly engages Akt/PKB survival signaling to support oncogenic transformation
YH Ou, M Torres, R Ram, E Formstecher, C Roland, T Cheng, R Brekken, ...
Molecular cell 41 (4), 458-470, 2011
2602011
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