The epichaperome is an integrated chaperome network that facilitates tumour survival A Rodina, T Wang, P Yan, EDG Gomes, MPS Dunphy, N Pillarsetty, ... Nature 538 (7625), 397-401, 2016 | 248 | 2016 |
Paralog-selective Hsp90 inhibitors define tumor-specific regulation of HER2 PD Patel, P Yan, PM Seidler, HJ Patel, W Sun, C Yang, NS Que, ... Nature chemical biology 9 (11), 677-684, 2013 | 210 | 2013 |
Improved targeting of JAK2 leads to increased therapeutic efficacy in myeloproliferative neoplasms N Bhagwat, P Koppikar, M Keller, S Marubayashi, K Shank, R Rampal, ... Blood, The Journal of the American Society of Hematology 123 (13), 2075-2083, 2014 | 119 | 2014 |
Heat shock protein (HSP) drug discovery and development: targeting heat shock proteins in disease L Shrestha, A Bolaender, H J Patel, T Taldone Current topics in medicinal chemistry 16 (25), 2753-2764, 2016 | 115 | 2016 |
Advances in the discovery and development of heat-shock protein 90 inhibitors for cancer treatment HJ Patel, S Modi, G Chiosis, T Taldone Expert opinion on drug discovery 6 (5), 559-587, 2011 | 109 | 2011 |
Survey of data mining techniques used in healthcare domain S Patel, H Patel International Journal of Information 6 (1/2), 53-60, 2016 | 106 | 2016 |
Identification of an allosteric pocket on human hsp70 reveals a mode of inhibition of this therapeutically important protein A Rodina, PD Patel, Y Kang, Y Patel, I Baaklini, MJH Wong, T Taldone, ... Chemistry & biology 20 (12), 1469-1480, 2013 | 106 | 2013 |
Chemical tools to investigate mechanisms associated with HSP90 and HSP70 in disease L Shrestha, HJ Patel, G Chiosis Cell chemical biology 23 (1), 158-172, 2016 | 77 | 2016 |
Experimental and structural testing module to analyze paralogue-specificity and affinity in the Hsp90 inhibitors series T Taldone, PD Patel, M Patel, HJ Patel, CE Evans, A Rodina, S Ochiana, ... Journal of medicinal chemistry 56 (17), 6803-6818, 2013 | 77 | 2013 |
Heat shock protein 70 inhibitors. 1. 2, 5′-thiodipyrimidine and 5-(phenylthio) pyrimidine acrylamides as irreversible binders to an allosteric site on heat shock protein 70 Y Kang, T Taldone, HJ Patel, PD Patel, A Rodina, A Gozman, R Maharaj, ... Journal of medicinal chemistry 57 (4), 1188-1207, 2014 | 70 | 2014 |
Heat shock protein 70 inhibitors. 2. 2, 5′-thiodipyrimidines, 5-(phenylthio) pyrimidines, 2-(pyridin-3-ylthio) pyrimidines, and 3-(phenylthio) pyridines as reversible binders … T Taldone, Y Kang, HJ Patel, MR Patel, PD Patel, A Rodina, Y Patel, ... Journal of medicinal chemistry 57 (4), 1208-1224, 2014 | 67 | 2014 |
Synthesis and anticonvulsant activity of new N-1′, N-3′-disubstituted-2′ H, 3H, 5′ H-spiro-(2-benzofuran-1, 4′-imidazolidine)-2′, 3, 5′-triones HJ Patel, J Sarra, F Caruso, M Rossi, U Doshi, RA Stephani Bioorganic & medicinal chemistry letters 16 (17), 4644-4647, 2006 | 63 | 2006 |
Structure–activity relationship in a purine-scaffold compound series with selectivity for the endoplasmic reticulum Hsp90 paralog Grp94 HJ Patel, PD Patel, SO Ochiana, P Yan, W Sun, MR Patel, SK Shah, ... Journal of medicinal chemistry 58 (9), 3922-3943, 2015 | 59 | 2015 |
Protein chaperones: a composition of matter review (2008–2013) T Taldone, HJ Patel, A Bolaender, MR Patel, G Chiosis Expert opinion on therapeutic patents 24 (5), 501-518, 2014 | 53 | 2014 |
Different techniques to reduce the PAPR in OFDM system M Chauhan, S Patel, H Patel International Journal of Engineering Research and Applications (IJERA) 2 (3 …, 2012 | 45 | 2012 |
Molecular stressors engender protein connectivity dysfunction through aberrant N-glycosylation of a chaperone P Yan, HJ Patel, S Sharma, A Corben, T Wang, P Panchal, C Yang, ... Cell reports 31 (13), 2020 | 39 | 2020 |
Nanotechnology: Innovative applications in the oil and gas industry MF Fakoya, H Patel, SN Shah International Journal of Global Advanced Materials and Nanotechnology 1 (1 …, 2018 | 34 | 2018 |
Detection of quality in orange fruit image using SVM classifier H Patel, R Prajapati, M Patel 2019 3rd International Conference on Trends in Electronics and Informatics …, 2019 | 32 | 2019 |
Electronic tongue: A new taste sensor H Jain, R Panchal, P Pradhan, H Patel, TY Pasha International Journal of Pharmaceutical Sciences Review and Research 5 (2 …, 2010 | 27 | 2010 |
Mutations in the yeast Hsp70, Ssa1, at P417 alter ATP cycling, interdomain coupling, and specific chaperone functions PG Needham, HJ Patel, G Chiosis, PH Thibodeau, JL Brodsky Journal of molecular biology 427 (18), 2948-2965, 2015 | 24 | 2015 |