Synthesis and tumor inhibitory activity of novel coumarin analogs targeting angiogenesis and apoptosis BRV Avin, P Thirusangu, VL Ranganatha, A Firdouse, BT Prabhakar, ... European journal of medicinal chemistry 75, 211-221, 2014 | 120 | 2014 |
Repurposing quinacrine for treatment-refractory cancer DB Oien, CL Pathoulas, U Ray, P Thirusangu, E Kalogera, V Shridhar Seminars in Cancer Biology 68, 21-30, 2021 | 72 | 2021 |
Synthesis and evaluation of novel benzophenone-thiazole derivatives as potent VEGF-A inhibitors T Prashanth, P Thirusangu, BRV Avin, VL Ranganatha, BT Prabhakar, ... European journal of medicinal chemistry 87, 274-283, 2014 | 54 | 2014 |
BP-1T, an antiangiogenic benzophenone-thiazole pharmacophore, counteracts HIF-1 signalling through p53/MDM2-mediated HIF-1α proteasomal degradation P Thirusangu, V Vigneshwaran, T Prashanth, BRV Avin, VH Malojirao, ... Angiogenesis 20 (1), 55–71, 2017 | 52 | 2017 |
Synthesis, angiopreventive activity, and in vivo tumor inhibition of novel benzophenone–benzimidazole analogs VL Ranganatha, BRV Avin, P Thirusangu, T Prashanth, BT Prabhakar, ... Life sciences 93 (23), 904-911, 2013 | 52 | 2013 |
Synthesis of coumarin analogs appended with quinoline and thiazole moiety and their apoptogenic role against murine ascitic carcinoma T Prashanth, BRV Avin, P Thirusangu, VL Ranganatha, BT Prabhakar, ... Biomedicine & Pharmacotherapy 112, 108707, 2019 | 48 | 2019 |
A tumoural angiogenic gateway blocker, Benzophenone-1B represses the HIF-1α nuclear translocation and its target gene activation against neoplastic progression P Thirusangu, V Vigneshwaran, VL Ranganatha, BRV Avin, SA Khanum, ... Biochemical Pharmacology 125, 26-40, 2017 | 46 | 2017 |
Inhibition of PFKFB3 induces cell death and synergistically enhances chemosensitivity in endometrial cancer Y Xiao, L Jin, C Deng, Y Guan, E Kalogera, U Ray, P Thirusangu, J Staub, ... Oncogene, 1-16, 2021 | 44 | 2021 |
PFKFB3 regulates cancer stemness through the hippo pathway in small cell lung carcinoma P Thirusangu, U Ray, S Sarkar Bhattacharya, DB Oien, L Jin, J Staub, ... Oncogene 41 (33), 4003-4017, 2022 | 42 | 2022 |
Targeting LRRC15 inhibits metastatic dissemination of ovarian cancer U Ray, DB Jung, L Jin, Y Xiao, S Dasari, S Sarkar Bhattacharya, ... Cancer research 82 (6), 1038-1054, 2022 | 40 | 2022 |
DAO-9 (2, 5-di (4-aryloylaryloxymethyl)-1, 3, 4-oxadiazole) exhibits p53 induced apoptogenesis through caspase-3 mediated endonuclease activity in murine carcinoma HD Gurupadaswamy, P Thirusangu, BRV Avin, V Vigneshwaran, ... Biomedicine & Pharmacotherapy 68 (6), 791-797, 2014 | 39 | 2014 |
Synthesis and antiproliferative activity of benzophenone tagged pyridine analogues towards activation of caspase activated DNase mediated nuclear fragmentation in Dalton’s lymphoma M Al-Ghorbani, P Thirusangu, HD Gurupadaswamy, V Girish, ... Bioorganic chemistry 65, 73-81, 2016 | 38 | 2016 |
New role of lupeol in reticence of angiogenesis, the cellular parameter of neoplastic progression in tumorigenesis models through altered gene expression BRV Avin, T Prabhu, CK Ramesh, V Vigneshwaran, M Riaz, K Jayashree, ... Biochemical and Biophysical Research Communications 448 (2), 139-144, 2014 | 38 | 2014 |
PFKFB3 inhibition reprograms malignant pleural mesothelioma to nutrient stress-induced macropinocytosis and ER stress as independent binary adaptive responses S Sarkar Bhattacharya, P Thirusangu, L Jin, D Roy, D Jung, Y Xiao, ... Cell Death & Disease 10 (10), 725, 2019 | 37 | 2019 |
The Novel 4-Phenyl-2-Phenoxyacetamide Thiazoles modulates the tumor hypoxia leading to the crackdown of neoangiogenesis and evoking the cell death YHE Mohammed, VH Malojirao, P Thirusangu, M Al-Ghorbani, ... European journal of medicinal chemistry 143, 1826-1839, 2018 | 33 | 2018 |
Scutellarein antagonizes the tumorigenesis by modulating cytokine VEGF mediated neoangiogenesis and DFF-40 actuated nucleosomal degradation P Thirusangu, V Vigneshwaran, BRV Avin, H Rakesh, HM Vikas, ... Biochemical and biophysical research communications 484 (1), 85-92, 2017 | 31 | 2017 |
Immunomodulatory glc/man-directed Dolichos lablab lectin (DLL) evokes anti-tumour response in vivo by counteracting angiogenic gene expressions V Vigneshwaran, P Thirusangu, BR Vijay Avin, V Krishna, SN Pramod, ... Clinical & Experimental Immunology 189 (1), 21-35, 2017 | 29 | 2017 |
The latex sap of the ‘Old World Plant’Lagenaria siceraria with potent lectin activity mitigates neoplastic malignancy targeting neovasculature and cell death V Vigneshwaran, P Thirusangu, S Madhusudana, V Krishna, SN Pramod, ... International Immunopharmacology 39, 158-171, 2016 | 27 | 2016 |
The anti-invasive role of novel synthesized pyridazine hydrazide appended phenoxy acetic acid against neoplastic development targeting matrix metallo proteases YHE Mohammed, P Thirusangu, V Vigneshwaran, BT Prabhakar, ... Biomedicine & Pharmacotherapy 95, 375-386, 2017 | 25 | 2017 |
Synthesis and an angiolytic role of novel piperazine–benzothiazole analogues on neovascularization, a chief tumoral parameter in neoplastic development M Al-Ghorbani, GS Pavankumar, P Naveen, P Thirusangu, BT Prabhakar, ... Bioorganic chemistry 65, 110-117, 2016 | 24 | 2016 |