Association analysis identifies 65 new breast cancer risk loci K Michailidou, S Lindström, J Dennis, J Beesley, S Hui, S Kar, A Lemaçon, ... Nature 551 (7678), 92-94, 2017 | 1228 | 2017 |
Identification of 12 new susceptibility loci for different histotypes of epithelial ovarian cancer CM Phelan, KB Kuchenbaecker, JP Tyrer, SP Kar, K Lawrenson, ... Nature genetics 49 (5), 680-691, 2017 | 364 | 2017 |
Identification of ten variants associated with risk of estrogen-receptor-negative breast cancer RL Milne, KB Kuchenbaecker, K Michailidou, J Beesley, S Kar, ... Nature genetics 49 (12), 1767-1778, 2017 | 322 | 2017 |
Intravenous autologous bone marrow mononuclear cells for ischemic stroke SI Savitz, V Misra, M Kasam, H Juneja, CS Cox Jr, S Alderman, I Aisiku, ... Annals of neurology 70 (1), 59-69, 2011 | 317 | 2011 |
Genetic predisposition to mosaic Y chromosome loss in blood DJ Thompson, G Genovese, J Halvardson, JC Ulirsch, DJ Wright, C Terao, ... Nature 575 (7784), 652-657, 2019 | 187 | 2019 |
Genome-wide meta-analyses of breast, ovarian, and prostate cancer association studies identify multiple new susceptibility loci shared by at least two cancer types SP Kar, J Beesley, A Amin Al Olama, K Michailidou, J Tyrer, ZS Kote-Jarai, ... Cancer discovery 6 (9), 1052-1067, 2016 | 177 | 2016 |
Breast cancer risk variants at 6q25 display different phenotype associations and regulate ESR1, RMND1 and CCDC170 AM Dunning, K Michailidou, KB Kuchenbaecker, D Thompson, JD French, ... Nature genetics 48 (4), 374-386, 2016 | 145 | 2016 |
Fine-mapping of 150 breast cancer risk regions identifies 191 likely target genes L Fachal, H Aschard, J Beesley, DR Barnes, J Allen, S Kar, KA Pooley, ... Nature genetics 52 (1), 56-73, 2020 | 143 | 2020 |
Biomarkers of TGF-β signaling pathway and prognosis of pancreatic cancer M Javle, Y Li, D Tan, X Dong, P Chang, S Kar, D Li PloS one 9 (1), e85942, 2014 | 140 | 2014 |
Evidence that breast cancer risk at the 2q35 locus is mediated through IGFBP5 regulation M Ghoussaini, SL Edwards, K Michailidou, S Nord, R Cowper-Sal· lari, ... Nature communications 5 (1), 4999, 2014 | 130 | 2014 |
Identification of four novel susceptibility loci for oestrogen receptor negative breast cancer FJ Couch, KB Kuchenbaecker, K Michailidou, GA Mendoza-Fandino, ... Nature communications 7 (1), 11375, 2016 | 121 | 2016 |
Smoking, alcohol consumption, and cancer: a mendelian randomisation study in UK Biobank and international genetic consortia participants SC Larsson, P Carter, S Kar, M Vithayathil, AM Mason, K Michaëlsson, ... PLoS medicine 17 (7), e1003178, 2020 | 107 | 2020 |
Genome-wide analyses of 200,453 individuals yield new insights into the causes and consequences of clonal hematopoiesis SP Kar, PM Quiros, M Gu, T Jiang, J Mitchell, R Langdon, V Iyer, ... Nature Genetics 54 (8), 1155-1166, 2022 | 95 | 2022 |
Fine-scale mapping of the 5q11. 2 breast cancer locus reveals at least three independent risk variants regulating MAP3K1 DM Glubb, MJ Maranian, K Michailidou, KA Pooley, KB Meyer, S Kar, ... The American Journal of Human Genetics 96 (1), 5-20, 2015 | 89 | 2015 |
Expression QTL-based analyses reveal candidate causal genes and loci across five tumor types Q Li, A Stram, C Chen, S Kar, S Gayther, P Pharoah, C Haiman, ... Human molecular genetics 23 (19), 5294-5302, 2014 | 89 | 2014 |
Molecular characterization of gallbladder cancer using somatic mutation profiling M Javle, A Rashid, C Churi, S Kar, M Zuo, AK Eterovic, ... Human pathology 45 (4), 701-708, 2014 | 88 | 2014 |
Functional mechanisms underlying pleiotropic risk alleles at the 19p13. 1 breast–ovarian cancer susceptibility locus K Lawrenson, S Kar, K McCue, K Kuchenbaeker, K Michailidou, J Tyrer, ... Nature communications 7 (1), 12675, 2016 | 87 | 2016 |
A transcriptome-wide association study of high-grade serous epithelial ovarian cancer identifies new susceptibility genes and splice variants A Gusev, K Lawrenson, X Lin, PC Lyra Jr, S Kar, KC Vavra, F Segato, ... Nature genetics 51 (5), 815-823, 2019 | 84 | 2019 |
Cis-eQTL analysis and functional validation of candidate susceptibility genes for high-grade serous ovarian cancer K Lawrenson, Q Li, S Kar, JH Seo, J Tyrer, TJ Spindler, J Lee, Y Chen, ... Nature communications 6 (1), 8234, 2015 | 77 | 2015 |
Is type 2 diabetes causally associated with cancer risk? Evidence from a two-sample Mendelian randomization study S Yuan, S Kar, P Carter, M Vithayathil, AM Mason, S Burgess, SC Larsson Diabetes 69 (7), 1588-1596, 2020 | 76 | 2020 |