Janet Siliciano
Janet Siliciano
Associate Professor of Medicine, Johns Hopkins University School of Medicine
Verified email at
Cited by
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Latent infection of CD4+ T cells provides a mechanism for lifelong persistence of HIV-1, even in patients on effective combination therapy
D Finzi, J Blankson, JD Siliciano, JB Margolick, K Chadwick, T Pierson, ...
Nature medicine 5 (5), 512-517, 1999
Activation of the ATM kinase by ionizing radiation and phosphorylation of p53
CE Canman, DS Lim, KA Cimprich, Y Taya, K Tamai, K Sakaguchi, ...
Science 281 (5383), 1677-1679, 1998
Long-term follow-up studies confirm the stability of the latent reservoir for HIV-1 in resting CD4+ T cells
JD Siliciano, J Kajdas, D Finzi, TC Quinn, K Chadwick, JB Margolick, ...
Nature medicine 9 (6), 727-728, 2003
Identification of ZO-1: a high molecular weight polypeptide associated with the tight junction (zonula occludens) in a variety of epithelia.
BR Stevenson, JD Siliciano, MS Mooseker, DA Goodenough
The Journal of cell biology 103 (3), 755-766, 1986
Replication-competent noninduced proviruses in the latent reservoir increase barrier to HIV-1 cure
YC Ho, L Shan, NN Hosmane, J Wang, SB Laskey, DIS Rosenbloom, ...
Cell 155 (3), 540-551, 2013
DNA damage induces phosphorylation of the amino terminus of p53
JD Siliciano, CE Canman, Y Taya, K Sakaguchi, E Appella, MB Kastan
Genes & development 11 (24), 3471-3481, 1997
Defective proviruses rapidly accumulate during acute HIV-1 infection
KM Bruner, AJ Murray, RA Pollack, MG Soliman, SB Laskey, AA Capoferri, ...
Nature medicine 22 (9), 1043-1049, 2016
Comparative analysis of measures of viral reservoirs in HIV-1 eradication studies
S Eriksson, EH Graf, V Dahl, MC Strain, SA Yukl, ES Lysenko, RJ Bosch, ...
PLoS pathogens 9 (2), e1003174, 2013
A quantitative approach for measuring the reservoir of latent HIV-1 proviruses
KM Bruner, Z Wang, FR Simonetti, AM Bender, KJ Kwon, S Sengupta, ...
Nature 566 (7742), 120-125, 2019
Broad CTL response is required to clear latent HIV-1 due to dominance of escape mutations
K Deng, M Pertea, A Rongvaux, L Wang, CM Durand, G Ghiaur, J Lai, ...
Nature 517 (7534), 381-385, 2015
New ex vivo approaches distinguish effective and ineffective single agents for reversing HIV-1 latency in vivo
CK Bullen, GM Laird, CM Durand, JD Siliciano, RF Siliciano
Nature medicine 20 (4), 425-429, 2014
A vinculin-containing cortical lattice in skeletal muscle: transverse lattice elements (" costameres") mark sites of attachment between myofibrils and sarcolemma.
JV Pardo, JD Siliciano, SW Craig
Proceedings of the National Academy of Sciences 80 (4), 1008-1012, 1983
Residual human immunodeficiency virus type 1 viremia in some patients on antiretroviral therapy is dominated by a small number of invariant clones rarely found in circulating …
JR Bailey, AR Sedaghat, T Kieffer, T Brennan, PK Lee, M Wind-Rotolo, ...
Journal of virology 80 (13), 6441-6457, 2006
HIV-1 integration landscape during latent and active infection
LB Cohn, IT Silva, TY Oliveira, RA Rosales, EH Parrish, GH Learn, ...
Cell 160 (3), 420-432, 2015
International AIDS Society global scientific strategy: towards an HIV cure 2016
SG Deeks, SR Lewin, AL Ross, J Ananworanich, M Benkirane, P Cannon, ...
Nature medicine 22 (8), 839-850, 2016
Resting CD4+ T Cells from Human Immunodeficiency Virus Type 1 (HIV-1)-Infected Individuals Carry Integrated HIV-1 Genomes within Actively Transcribed Host …
Y Han, K Lassen, D Monie, AR Sedaghat, S Shimoji, X Liu, TC Pierson, ...
Journal of virology 78 (12), 6122-6133, 2004
Ex vivo analysis identifies effective HIV-1 latency–reversing drug combinations
GM Laird, CK Bullen, DIS Rosenbloom, AR Martin, AL Hill, CM Durand, ...
The Journal of clinical investigation 125 (5), 1901-1912, 2015
Proliferation of latently infected CD4+ T cells carrying replication-competent HIV-1: Potential role in latent reservoir dynamics
NN Hosmane, KJ Kwon, KM Bruner, AA Capoferri, S Beg, ...
Journal of Experimental Medicine 214 (4), 959-972, 2017
Challenges in detecting HIV persistence during potentially curative interventions: a study of the Berlin patient
SA Yukl, E Boritz, M Busch, C Bentsen, TW Chun, D Douek, E Eisele, ...
PLoS pathogens 9 (5), e1003347, 2013
Isolation and characterization of replication-competent human immunodeficiency virus type 1 from a subset of elite suppressors
JN Blankson, JR Bailey, S Thayil, HC Yang, K Lassen, J Lai, SK Gandhi, ...
Journal of virology 81 (5), 2508-2518, 2007
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