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Microbial exposure during early human development primes fetal immune cells
A Mishra, GC Lai, LJ Yao, TT Aung, N Shental, A Rotter-Maskowitz, ...
Cell 184 (13), 3394-3409. e20, 2021
1702021
Amino acid modified xanthone derivatives: novel, highly promising membrane-active antimicrobials for multidrug-resistant Gram-positive bacterial infections
JJ Koh, S Lin, TT Aung, F Lim, H Zou, Y Bai, J Li, H Lin, LM Pang, WL Koh, ...
Journal of medicinal chemistry 58 (2), 739-752, 2015
1302015
Design and synthesis of amphiphilic xanthone-based, membrane-targeting antimicrobials with improved membrane selectivity
H Zou, JJ Koh, J Li, S Qiu, TT Aung, H Lin, R Lakshminarayanan, X Dai, ...
Journal of medicinal chemistry 56 (6), 2359-2373, 2013
1152013
Design and synthesis of amphiphilic xanthone-based, membrane-targeting antimicrobials with improved membrane selectivity
H Zou, JJ Koh, J Li, S Qiu, TT Aung, H Lin, R Lakshminarayanan, X Dai, ...
Journal of medicinal chemistry 56 (6), 2359-2373, 2013
1152013
Symmetrically substituted xanthone amphiphiles combat gram-positive bacterial resistance with enhanced membrane selectivity
S Lin, JJ Koh, TT Aung, F Lim, J Li, H Zou, L Wang, R Lakshminarayanan, ...
Journal of medicinal chemistry 60 (4), 1362-1378, 2017
772017
Semisynthetic Flavone-Derived Antimicrobials with Therapeutic Potential against Methicillin-Resistant Staphylococcus aureus (MRSA)
S Lin, JJ Koh, TT Aung, WLW Sin, F Lim, L Wang, R Lakshminarayanan, ...
Journal of Medicinal Chemistry 60 (14), 6152-6165, 2017
742017
Multifunctional antimicrobial nanofiber dressings containing ε-polylysine for the eradication of bacterial bioburden and promotion of wound healing in critically colonized wounds
V Mayandi, AC Wen Choong, C Dhand, FP Lim, TT Aung, H Sriram, ...
ACS applied materials & interfaces 12 (14), 15989-16005, 2020
732020
Biofilms of pathogenic nontuberculous mycobacteria targeted by new therapeutic approaches
TT Aung, JKH Yam, S Lin, SM Salleh, M Givskov, S Liu, NC Lwin, L Yang, ...
Antimicrobial agents and chemotherapy 60 (1), 24-35, 2016
682016
Antimicrobial activity and cell selectivity of synthetic and biosynthetic cationic polymers
M Venkatesh, VA Barathi, ETL Goh, R Anggara, MHUT Fazil, AJY Ng, ...
Antimicrobial agents and chemotherapy 61 (10), 10.1128/aac. 00469-17, 2017
572017
N-lipidated peptide dimers: effective antibacterial agents against gram-negative pathogens through lipopolysaccharide permeabilization
JJ Koh, H Lin, V Caroline, YS Chew, LM Pang, TT Aung, J Li, ...
Journal of medicinal chemistry 58 (16), 6533-6548, 2015
482015
Synthetic multivalent antifungal peptides effective against fungi
R Lakshminarayanan, S Liu, J Li, M Nandhakumar, TT Aung, E Goh, ...
PLoS One 9 (2), e87730, 2014
422014
Surface immobilization of nano-silver on polymeric medical devices to prevent bacterial biofilm formation
AK Riau, TT Aung, M Setiawan, L Yang, G HF Yam, R W. Beuerman, ...
Pathogens 8 (3), 93, 2019
402019
Branched peptide, B2088, disrupts the supramolecular organization of lipopolysaccharides and sensitizes the gram-negative bacteria
R Lakshminarayanan, WX Tan, TT Aung, ETL Goh, N Muruganantham, ...
Scientific reports 6 (1), 25905, 2016
352016
Repurposing the anticancer drug cisplatin with the aim of developing novel Pseudomonas aeruginosa infection control agents
M Yuan, SL Chua, Y Liu, DI Drautz-Moses, JKH Yam, TT Aung, ...
Beilstein journal of organic chemistry 14 (1), 3059-3069, 2018
312018
Experimental colonization with Blastocystis ST4 is associated with protective immune responses and modulation of gut microbiome in a DSS-induced colitis mouse …
L Deng, L Wojciech, CW Png, EY Koh, TT Aung, DYQ Kioh, ECY Chan, ...
Cellular and Molecular Life Sciences 79 (5), 245, 2022
302022
Collagen-based artificial corneal scaffold with anti-infective capability for prevention of perioperative bacterial infections
AK Riau, D Mondal, TT Aung, E Murugan, L Chen, NC Lwin, L Zhou, ...
ACS Biomaterials Science & Engineering 1 (12), 1324-1334, 2015
262015
Discovery of novel antimycobacterial drug therapy in biofilm of pathogenic nontuberculous mycobacterial keratitis
TT Aung, WHJ Chor, JKH Yam, M Givskov, L Yang, RW Beuerman
The Ocular Surface 15 (4), 770-783, 2017
192017
Antimicrobial activity profiles of amphiphilic xanthone derivatives are a function of their molecular oligomerization
JJ Koh, S Lin, Y Bai, WWL Sin, TT Aung, J Li, V Chandra, K Pervushin, ...
Biochimica et Biophysica Acta (BBA)-Biomembranes 1860 (11), 2281-2298, 2018
182018
Colonization with two different Blastocystis subtypes in DSS-induced colitis mice is associated with strikingly different microbiome and pathological features
L Deng, L Wojciech, CW Png, DYQ Kioh, Y Gu, TT Aung, B Malleret, ...
Theranostics 13 (3), 1165, 2023
162023
Hybrid derivative of cathelicidin and human beta defensin-2 against Gram-positive bacteria: A novel approach for the treatment of bacterial keratitis
DSJ Ting, ETL Goh, V Mayandi, JMF Busoy, TT Aung, MH Periayah, ...
Scientific Reports 11 (1), 18304, 2021
152021
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