| Strategic approaches to overcome resistance against Gram-negative pathogens using β-lactamase inhibitors and β-lactam enhancers: activity of three novel diazabicyclooctanes WCK … KM Papp-Wallace, NQ Nguyen, MR Jacobs, CR Bethel, MD Barnes, ... Journal of medicinal chemistry 61 (9), 4067-4086, 2018 | 127 | 2018 |
| Targeting Multidrug-Resistant Acinetobacter spp.: Sulbactam and the Diazabicyclooctenone β-Lactamase Inhibitor ETX2514 as a Novel Therapeutic Agent MD Barnes, V Kumar, CR Bethel, SH Moussa, J O’Donnell, JD Rutter, ... MBio 10 (2), 10.1128/mbio. 00159-19, 2019 | 76 | 2019 |
| Insights into BAY 60-2770 Activation and S-Nitrosylation-Dependent Desensitization of Soluble Guanylyl Cyclase via Crystal Structures of Homologous Nostoc H … V Kumar, F Martin, MG Hahn, M Schaefer, JS Stamler, JP Stasch, ... Biochemistry 52 (20), 3601-3608, 2013 | 62 | 2013 |
| Discovery of the soluble guanylate cyclase activator runcaciguat (BAY 1101042) MG Hahn, T Lampe, S El Sheikh, N Griebenow, E Woltering, ... Journal of Medicinal Chemistry 64 (9), 5323-5344, 2021 | 45 | 2021 |
| Insights into soluble guanylyl cyclase activation derived from improved heme-mimetics M von Wantoch Rekowski, V Kumar, Z Zhou, J Moschner, A Marazioti, ... Journal of medicinal chemistry 56 (21), 8948-8952, 2013 | 29 | 2013 |
| A γ-Lactam Siderophore Antibiotic Effective Against Multidrug-Resistant Gram-Negative Bacilli J Goldberg, H Nguyen, V Kumar, E Spencer, D Hoyer, E Marshall, ... Journal of Medicinal Chemistry, 2020 | 26 | 2020 |
| Development of a process for preparation of pure and blended kinnow wine without debittering kinnow mandarin juice K Pratima, K Vijay, D Niranjan, TS Mohan Food Saf. Inform. Publish 8, 24-29, 2006 | 22 | 2006 |
| Structural characterization of diazabicyclooctane β-lactam “enhancers” in complex with penicillin-binding proteins PBP2 and PBP3 of Pseudomonas aeruginosa M Rajavel, V Kumar, H Nguyen, J Wyatt, SH Marshall, KM Papp-Wallace, ... Mbio 12 (1), 10.1128/mbio. 03058-20, 2021 | 21 | 2021 |
| Structural characterization of the D179N and D179Y variants of KPC-2 β-lactamase: Ω-loop destabilization as a mechanism of resistance to ceftazidime-avibactam TA Alsenani, SL Viviani, V Kumar, MA Taracila, CR Bethel, MD Barnes, ... Antimicrobial Agents and Chemotherapy 66 (4), e02414-21, 2022 | 20 | 2022 |
| Replacement of the active surface of a thermophile protein by that of a homologous mesophile protein through structure-guided ‘protein surface grafting’ D Kapoor, V Kumar, SK Chandrayan, S Ahmed, S Sharma, M Datt, ... Biochimica et Biophysica Acta (BBA)-Proteins and Proteomics 1784 (11), 1771-1776, 2008 | 18 | 2008 |
| A γ-lactam siderophore antibiotic effective against multidrug-resistant Pseudomonas aeruginosa, Klebsiella pneumoniae, and Acinetobacter spp. JA Goldberg, V Kumar, EJ Spencer, D Hoyer, SH Marshall, AM Hujer, ... European journal of medicinal chemistry 220, 113436, 2021 | 15 | 2021 |
| Structural studies and molecular dynamics simulations suggest a processive mechanism of exolytic lytic transglycosylase from Campylobacter jejuni J Vijayaraghavan, V Kumar, NP Krishnan, RT Kaufhold, X Zeng, J Lin, ... PLoS One 13 (5), e0197136, 2018 | 14 | 2018 |
| Purification, crystallization and preliminary X-ray diffraction analysis of aspartate semialdehyde dehydrogenase (Rv3708c) from Mycobacterium tuberculosis R Vyas, V Kumar, S Panjikar, S Karthikeyan, KVR Kishan, R Tewari, ... Acta Crystallographica Section F: Structural Biology and Crystallization …, 2008 | 14 | 2008 |
| Structural analysis of the OXA-48 carbapenemase bound to a “poor” carbapenem substrate, doripenem KM Papp-Wallace, V Kumar, ET Zeiser, SA Becka, F van den Akker Antibiotics 8 (3), 145, 2019 | 13 | 2019 |
| Structural analysis of the boronic acid β-lactamase inhibitor vaborbactam binding to Pseudomonas aeruginosa penicillin-binding protein 3 V Kumar, SL Viviani, J Ismail, S Agarwal, RA Bonomo, F van den Akker PloS one 16 (10), e0258359, 2021 | 10 | 2021 |
| Carboxylated lysine is required for higher activities in hydantoinases V Kumar, N Saxena, M Sarma, KV Kishan Protein and peptide letters 18 (7), 663-669, 2011 | 10 | 2011 |
| Structural insights into ceftobiprole inhibition of Pseudomonas aeruginosa penicillin-binding protein 3 V Kumar, C Tang, CR Bethel, KM Papp-Wallace, J Wyatt, E Desarbre, ... Antimicrobial agents and chemotherapy 64 (5), 10.1128/aac. 00106-20, 2020 | 9 | 2020 |
| Turnover Chemistry and Structural Characterization of the Cj0843c Lytic Transglycosylase of Campylobacter jejuni V Kumar, SA Mathure, M Lee, J Boorman, X Zeng, J Lin, D Hesek, ... Biochemistry 60 (14), 1133-1144, 2021 | 4 | 2021 |
| Exploring the inhibition of the soluble lytic transglycosylase Cj0843c of Campylobacter jejuni via targeting different sites with different scaffolds V Kumar, J Boorman, WJ Greenlee, X Zeng, J Lin, F van den Akker Protein Science, e4683, 2023 | 1 | 2023 |
| Natural protein engineering in the Ω-loop: the role of Y221 in ceftazidime and ceftolozane resistance in Pseudomonas-derived cephalosporinase AR Mack, V Kumar, MA Taracila, MF Mojica, M O'Shea, W Schinabeck, ... Antimicrobial Agents and Chemotherapy 67 (11), e00791-23, 2023 | | 2023 |
