An iCRISPR platform for rapid, multiplexable, and inducible genome editing in human pluripotent stem cells F González, Z Zhu, ZD Shi, K Lelli, N Verma, QV Li, D Huangfu Cell stem cell 15 (2), 215-226, 2014 | 527 | 2014 |
Genome editing of lineage determinants in human pluripotent stem cells reveals mechanisms of pancreatic development and diabetes Z Zhu, QV Li, K Lee, BP Rosen, F González, CL Soh, D Huangfu Cell stem cell 18 (6), 755-768, 2016 | 181 | 2016 |
TET proteins safeguard bivalent promoters from de novo methylation in human embryonic stem cells N Verma, H Pan, LC Doré, A Shukla, QV Li, B Pelham-Webb, V Teijeiro, ... Nature genetics 50 (1), 83-95, 2018 | 172 | 2018 |
Genome Editing in hPSCs Reveals GATA6 Haploinsufficiency and a Genetic Interaction with GATA4 in Human Pancreatic Development DH Zhong-Dong Shi, Kihyun Lee, Dapeng Yang, Sadaf Amin, Nipun Verma, Qing V ... Cell Stem Cell 20 (1-14), 2017 | 157 | 2017 |
The p53 family coordinates Wnt and nodal inputs in mesendodermal differentiation of embryonic stem cells Q Wang, Y Zou, S Nowotschin, SY Kim, QV Li, CL Soh, J Su, C Zhang, ... Cell Stem Cell 20 (1), 70-86, 2017 | 152 | 2017 |
FOXA2 is required for enhancer priming during pancreatic differentiation K Lee, H Cho, RW Rickert, QV Li, J Pulecio, CS Leslie, D Huangfu Cell reports 28 (2), 382-393. e7, 2019 | 120 | 2019 |
Genome-scale screens identify JNK–JUN signaling as a barrier for pluripotency exit and endoderm differentiation QV Li, G Dixon, N Verma, BP Rosen, M Gordillo, R Luo, C Xu, Q Wang, ... Nature genetics 51 (6), 999-1010, 2019 | 99 | 2019 |
The S100P/RAGE signaling pathway regulates expression of microRNA-21 in colon cancer cells ME Mercado-Pimentel, BC Onyeagucha, Q Li, AC Pimentel, J Jandova, ... FEBS letters 589 (18), 2388-2393, 2015 | 59 | 2015 |
CRISPR screening uncovers a central requirement for HHEX in pancreatic lineage commitment and plasticity restriction D Yang, H Cho, Z Tayyebi, A Shukla, R Luo, G Dixon, V Ursu, S Stransky, ... Nature cell biology 24 (7), 1064-1076, 2022 | 19 | 2022 |
Decoding pluripotency: Genetic screens to interrogate the acquisition, maintenance, and exit of pluripotency QV Li, BP Rosen, D Huangfu Wiley Interdisciplinary Reviews: Systems Biology and Medicine 12 (1), e1464, 2020 | 12 | 2020 |
Dynamic network-guided CRISPRi screen identifies CTCF-loop-constrained nonlinear enhancer gene regulatory activity during cell state transitions R Luo, J Yan, JW Oh, W Xi, D Shigaki, W Wong, HS Cho, D Murphy, ... Nature genetics 55 (8), 1336-1346, 2023 | 7 | 2023 |
Parallel genome-scale CRISPR screens distinguish pluripotency and self-renewal BP Rosen, QV Li, H Cho, D Liu, D Yang, S Graff, J Yan, R Luo, N Verma, ... bioRxiv, 2023.05. 03.539283, 2023 | 1 | 2023 |