Comparative host-coronavirus protein interaction networks reveal pan-viral disease mechanisms DE Gordon, J Hiatt, M Bouhaddou, VV Rezelj, S Ulferts, H Braberg, ... Science 370 (6521), eabe9403, 2020 | 614 | 2020 |
An ultrapotent synthetic nanobody neutralizes SARS-CoV-2 by stabilizing inactive Spike M Schoof, B Faust, RA Saunders, S Sangwan, V Rezelj, N Hoppe, ... Science 370 (6523), 1473-1479, 2020 | 418* | 2020 |
Bi-paratopic and multivalent VH domains block ACE2 binding and neutralize SARS-CoV-2 CJ Bracken, SA Lim, P Solomon, NJ Rettko, DP Nguyen, BS Zha, ... Nature chemical biology 17 (1), 113-121, 2021 | 88 | 2021 |
CryoEM and AI reveal a structure of SARS-CoV-2 Nsp2, a multifunctional protein involved in key host processes M Gupta, CM Azumaya, M Moritz, S Pourmal, A Diallo, GE Merz, G Jang, ... bioRxiv, 2021 | 70 | 2021 |
Highlighting membrane protein structure and function: A celebration of the Protein Data Bank F Li, PF Egea, AJ Vecchio, I Asial, M Gupta, J Paulino, R Bajaj, ... Journal of Biological Chemistry 296, 2021 | 54 | 2021 |
Ceapins block the unfolded protein response sensor ATF6α by inducing a neomorphic inter-organelle tether SE Torres, CM Gallagher, L Plate, M Gupta, CR Liem, X Guo, R Tian, ... Elife 8, e46595, 2019 | 53 | 2019 |
Azole resistance in a Candida albicans mutant lacking the ABC transporter CDR6/ROA1 depends on TOR signaling NK Khandelwal, N Chauhan, P Sarkar, BD Esquivel, P Coccetti, A Singh, ... Journal of Biological Chemistry 293 (2), 412-432, 2018 | 53 | 2018 |
Vacuolar sequestration of azoles, a novel strategy of azole antifungal resistance conserved across pathogenic and nonpathogenic yeast NK Khandelwal, M Wasi, R Nair, M Gupta, M Kumar, AK Mondal, NA Gaur, ... Antimicrobial Agents and Chemotherapy 63 (3), 10.1128/aac. 01347-18, 2019 | 29 | 2019 |
Motifs Q and I are required for ATP hydrolysis but not for ATP binding in SWI2/SNF2 proteins M Nongkhlaw, M Gupta, SS Komath, R Muthuswami Biochemistry 51 (18), 3711-3722, 2012 | 24 | 2012 |
Viral E protein neutralizes BET protein-mediated post-entry antagonism of SARS-CoV-2 IP Chen, JE Longbotham, S McMahon, RK Suryawanshi, MM Khalid, ... Cell reports 40 (3), 2022 | 18 | 2022 |
Molecular basis of multistep voltage activation in plant two-pore channel 1 Miles Sasha Dickinson, Jinping Lu, Meghna Gupta, Irene Marten, Rainer ... Proceedings of the National Academy of Sciences 119 (9), e2110936119, 2022 | 13 | 2022 |
Key computational findings reveal proton transfer as driving the functional cycle in the phosphate transporter PiPT GAV Yu Liu, Chenghan Li, Meghna Gupta, Nidhi Verma, Atul Kumar Johri, Robert ... Proceedings of the National Academy of Sciences 118 (25), 2021 | 12 | 2021 |
Ligand‐induced conformation changes drive ATP hydrolysis and function in SMARCAL 1 M Gupta, M Mazumder, K Dhatchinamoorthy, M Nongkhlaw, DT Haokip, ... The FEBS journal 282 (19), 3841-3859, 2015 | 12 | 2015 |
Symmetry reduction in a hyperpolarization-activated homotetrameric ion channel MS Dickinson, S Pourmal, M Gupta, M Bi, RM Stroud Biochemistry, 2021 | 6 | 2021 |
Smart data collection for CryoEM T Bepler, AJ Borst, J Bouvette, G Cannone, S Chen, A Cheng, A Cheng, ... Journal of Structural Biology 214 (4), 107913, 2022 | 5 | 2022 |
Structural basis of prostaglandin efflux by MRP4 S Pourmal, E Green, R Bajaj, IE Chemmama, GM Knudsen, M Gupta, ... Nature Structural & Molecular Biology, 1-12, 2024 | 4 | 2024 |
Fun30 and Rtt109 Mediate Epigenetic Regulation of the DNA Damage Response Pathway in C. albicans PK Maurya, P Garai, K Goel, H Bhatt, A Dutta, A Goyal, S Dewasthale, ... Journal of Fungi 8 (6), 559, 2022 | 1 | 2022 |
Kinetic Network Modeling with Molecular Simulation Inputs: A Proton-Coupled Phosphate Symporter Y Liu, C Li, M Gupta, RM Stroud, GA Voth Biophysical Journal, 2024 | | 2024 |
The structural basis of prostaglandin efflux by MRP4 RM Stroud, S Pourmal, E Green, R Bajaj, IE Chemmama, G Knudsen, ... Biophysical Journal 123 (3), 396a, 2024 | | 2024 |
Recent advances in infectious disease research using cryo-electron tomography Frontiers in Molecular Biosciences 10, 2024 | | 2024 |