| BCL-2 family proteins: changing partners in the dance towards death J Kale, EJ Osterlund, DW Andrews Cell Death & Differentiation 25 (1), 65-80, 2018 | 1366 | 2018 |
| Mechanisms of action of Bcl-2 family proteins A Shamas-Din, J Kale, B Leber, DW Andrews Cold Spring Harbor perspectives in biology 5 (4), a008714, 2013 | 850 | 2013 |
| Drugs targeting Bcl-2 family members as an emerging strategy in cancer B Leber, F Geng, J Kale, DW Andrews Expert reviews in molecular medicine 12, e28, 2010 | 108 | 2010 |
| BH 3‐in‐groove dimerization initiates and helix 9 dimerization expands Bax pore assembly in membranes Z Zhang, S Subramaniam, J Kale, C Liao, B Huang, H Brahmbhatt, ... The EMBO journal 35 (2), 208-236, 2016 | 100 | 2016 |
| Shedding light on apoptosis at subcellular membranes J Kale, Q Liu, B Leber, DW Andrews Cell 151 (6), 1179-1184, 2012 | 93 | 2012 |
| Regulating cell death at, on, and in membranes X Chi, J Kale, B Leber, DW Andrews Biochimica et Biophysica Acta (BBA)-Molecular Cell Research 1843 (9), 2100-2113, 2014 | 89 | 2014 |
| After embedding in membranes antiapoptotic Bcl-XL protein binds both Bcl-2 homology region 3 and helix 1 of proapoptotic Bax protein to inhibit apoptotic mitochondrial … J Ding, BHM Mooers, Z Zhang, J Kale, D Falcone, J McNichol, B Huang, ... Journal of Biological Chemistry 289 (17), 11873-11896, 2014 | 83 | 2014 |
| Phosphorylation switches Bax from promoting to inhibiting apoptosis thereby increasing drug resistance J Kale, O Kutuk, GC Brito, TS Andrews, B Leber, A Letai, DW Andrews EMBO reports 19 (9), e45235, 2018 | 76 | 2018 |
| Bcl-xL acts as an inhibitor of IP3R channels, thereby antagonizing Ca2+-driven apoptosis N Rosa, H Ivanova, LE Wagner 2nd, J Kale, R La Rovere, ... Cell Death & Differentiation 29 (4), 788-805, 2022 | 46 | 2022 |
| Allosteric regulation of BH3 proteins in Bcl-xL complexes enables switch-like activation of Bax C Bogner, J Kale, J Pogmore, X Chi, A Shamas-Din, C Fradin, B Leber, ... Molecular Cell 77 (4), 901-912. e9, 2020 | 36 | 2020 |
| Examining the molecular mechanism of bcl-2 family proteins at membranes by fluorescence spectroscopy J Kale, X Chi, B Leber, D Andrews Methods in Enzymology 544, 1-23, 2014 | 32 | 2014 |
| Mechanisms of action of Bcl-2 family proteins. Cold Spring Harb Perspect Biol 5: a008714 A Shamas-Din, J Kale, B Leber, DW Andrews | 24 | 2013 |
| An amphipathic Bax core dimer forms part of the apoptotic pore wall in the mitochondrial␣ membrane F Lv, F Qi, Z Zhang, M Wen, J Kale, A Piai, L Du, S Wang, L Zhou, Y Yang, ... The EMBO journal 40 (14), e106438, 2021 | 23 | 2021 |
| Conformational heterogeneity of bax helix 9 dimer for apoptotic pore formation C Liao, Z Zhang, J Kale, DW Andrews, J Lin, J Li Scientific reports 6 (1), 29502, 2016 | 22 | 2016 |
| BDA-366, a putative Bcl-2 BH4 domain antagonist, induces apoptosis independently of Bcl-2 in a variety of cancer cell models T Vervloessem, BK Sasi, E Xerxa, S Karamanou, J Kale, RM La Rovere, ... Cell Death & Disease 11 (9), 769, 2020 | 20 | 2020 |
| Unleashing Blocked Apoptosis in Cancer Cells: New MCL1 Inhibitors Find Their Groove B Leber, J Kale, DW Andrews Cancer discovery 8 (12), 1511-1514, 2018 | 4 | 2018 |
| Characterization of the Activation Mechanism of Bax J Kale | | 2017 |
| Multi-molecular complexes of Bcl-2 proteins regulate membrane permeabilization by Bax C Bogner, J Kale, X Chi, B Leber, D Andrews Oncology Research and Treatment 38, 99-100, 2015 | | 2015 |
| BH3-in-groove dimer interface that initiates mitochondrial Bax oligomerization rearranges to form a pore complex with an additional helix 9 dimer interface. J Lin, Z Zhang, S Subramaniam, J Kale, A Senes, DW Andrews MOLECULAR BIOLOGY OF THE CELL 25, 2014 | | 2014 |
| Conformation dictates function: Membrane associated interactions of Bcl-XL with Bax, c (t) Bid and Bad C Bogner, J Kale, X Chi, A Shamas-Din, B Leber, DW Andrews ONCOLOGY RESEARCH AND TREATMENT 37, 280-280, 2014 | | 2014 |
