| Simulation of the undiseased human cardiac ventricular action potential: model formulation and experimental validation T O'Hara, L Virág, A Varró, Y Rudy PLoS computational biology 7 (5), e1002061, 2011 | 1289 | 2011 |
| Cardiac electrophysiological substrate underlying the ECG phenotype and electrogram abnormalities in Brugada syndrome patients J Zhang, F Sacher, K Hoffmayer, T O’Hara, M Strom, P Cuculich, J Silva, ... Circulation 131 (22), 1950-1959, 2015 | 180 | 2015 |
| Physiological properties of hERG 1a/1b heteromeric currents and a hERG 1b-specific mutation associated with Long-QT syndrome H Sale, J Wang, TJ O'Hara, DJ Tester, P Phartiyal, JQ He, Y Rudy, ... Circulation research 103 (7), e81-e95, 2008 | 157 | 2008 |
| Quantitative comparison of cardiac ventricular myocyte electrophysiology and response to drugs in human and nonhuman species T O'Hara, Y Rudy American Journal of Physiology-Heart and Circulatory Physiology 302 (5 …, 2012 | 152 | 2012 |
| Caveolin-3 regulates compartmentation of cardiomyocyte beta2-adrenergic receptor-mediated cAMP signaling PT Wright, VO Nikolaev, T O'Hara, I Diakonov, A Bhargava, S Tokar, ... Journal of molecular and cellular cardiology 67, 38-48, 2014 | 129 | 2014 |
| Microdomain-specific modulation of L-type calcium channels leads to triggered ventricular arrhythmia in heart failure JL Sanchez-Alonso, A Bhargava, T O’Hara, AV Glukhov, ... Circulation research 119 (8), 944-955, 2016 | 116 | 2016 |
| Simultaneous electrical recording of cardiac electrophysiology and contraction on chip F Qian, C Huang, YD Lin, AN Ivanovskaya, TJ O'Hara, RH Booth, ... Lab on a Chip 17 (10), 1732-1739, 2017 | 113 | 2017 |
| Early somatic mosaicism is a rare cause of long-QT syndrome JR Priest, C Gawad, KM Kahlig, JK Yu, T O’Hara, PM Boyle, S Rajamani, ... Proceedings of the National Academy of Sciences 113 (41), 11555-11560, 2016 | 50 | 2016 |
| Arrhythmia formation in subclinical (“silent”) long QT syndrome requires multiple insults: quantitative mechanistic study using the KCNQ1 mutation Q357R as example T O'Hara, Y Rudy Heart Rhythm 9 (2), 275-282, 2012 | 49 | 2012 |
| Subepicardial phase 0 block and discontinuous transmural conduction underlie right precordial ST-segment elevation by a SCN5A loss-of-function mutation M Bébarová, T O'Hara, JLMC Geelen, RJ Jongbloed, C Timmermans, ... American Journal of Physiology-Heart and Circulatory Physiology 295 (1), H48-H58, 2008 | 46 | 2008 |
| Computational cardiology: how computer simulations could be used to develop new therapies and advance existing ones NA Trayanova, T O'Hara, JD Bayer, PM Boyle, KS McDowell, ... Europace 14 (suppl_5), v82-v89, 2012 | 41 | 2012 |
| Dysfunction of the Voltage‐Gated K+ Channel β2 Subunit in a Familial Case of Brugada Syndrome V Portero, S Le Scouarnec, Z Es‐Salah‐Lamoureux, S Burel, ... Journal of the American Heart Association 5 (6), e003122, 2016 | 32 | 2016 |
| Complex Brugada syndrome inheritance in a family harbouring compound SCN5A and CACNA1C mutations DM Béziau, J Barc, T O’Hara, L Le Gloan, MY Amarouch, A Solnon, ... Basic research in cardiology 109, 1-15, 2014 | 32 | 2014 |
| Degradation of T-tubular microdomains and altered cAMP compartmentation lead to emergence of arrhythmogenic triggers in heart failure myocytes: an in silico study AD Loucks, T O’Hara, NA Trayanova Frontiers in Physiology 9, 403555, 2018 | 12 | 2018 |
| Efficient computational modeling of human ventricular activation and its electrocardiographic representation: A sensitivity study JP Cranford, TJ O’Hara, CT Villongco, OM Hafez, RC Blake, J Loscalzo, ... Cardiovascular engineering and technology 9, 447-467, 2018 | 8 | 2018 |
| Caveolin-3 and Caveolae regulate ventricular repolarization YS Markandeya, ZR Gregorich, L Feng, V Ramchandran, T O'Hara, ... Journal of Molecular and Cellular Cardiology 177, 38-49, 2023 | 4 | 2023 |
| Economical utilization of health information with learning healthcare system data commons T O'Hara, A Saldanha, M Trunnell, RL Grossman, B Hota, ... Perspectives in Health Information Management 19 (Spring), 2022 | 3 | 2022 |
| Cardioid J Cranford, D Richards, X Zhang, S Laudenschlager, J Glosli, T O'Hara, ... Lawrence Livermore National Laboratory (LLNL), Livermore, CA (United States), 2018 | 2 | 2018 |
| Cardiac-specific deletion of caveolin-3 delays repolarization and increases susceptibility to ventricular arrhythmia YS Markandeya, L Feng, V Ramchandran, R Vaidyanathan, J Best, ... Circulation 132 (suppl_3), A19749-A19749, 2015 | 2 | 2015 |
| hERG 1b as a potential target for inherited and acquired long QT syndrome GA Robertson, H Sale, D Tester, TJ O’Hara, P Phartiyal, J Wang, JQ He, ... Circulation 118 (suppl_18), S_525-S_525, 2008 | 2 | 2008 |
Natalia TrayanovaJohns Hopkins UniversityVerified email at jhu.edu
