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Girdhar Singh Deora
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Discovery and structure–activity relationships of a highly selective butyrylcholinesterase inhibitor by structure-based virtual screening
SN Dighe, GS Deora, E De la Mora, F Nachon, S Chan, MO Parat, ...
Journal of medicinal chemistry 59 (16), 7683-7689, 2016
1482016
Novel N-indolylmethyl substituted olanzapine derivatives: Their design, synthesis and evaluation as PDE4B inhibitors
DR Gorja, S Mukherjee, CLT Meda, GS Deora, K Lalith Kumar, A Jain, ...
Org. Biomol. Chem. 11, 2075-2079, 2013
702013
Synthesis and evaluation of 3-amino/guanidine substituted phenyl oxazoles as a novel class of LSD1 inhibitors with anti-proliferative properties
B Dulla, KT Kirla, V Rathore, GS Deora, S Kavela, S Maddika, K Chatti, ...
Organic & biomolecular chemistry 11, 3103, 2013
672013
Synthesis and pharmacological evaluation of pyrazolo [4, 3-< i> c</i>] cinnoline derivatives as potential anti-inflammatory and antibacterial agents
RK Tonk, S Bawa, G Chawla, GS Deora, S Kumar, V Rathore, ...
European Journal of Medicinal Chemistry 57, 176-184, 2012
632012
Synthesis of some coumarinyl chalcones and their antiproliferative activity against breast cancer cell lines
K Patel, C Karthikeyan, V Raja Solomon, N S Hari Narayana Moorthy, ...
Letters in Drug Design & Discovery 8 (4), 308-311, 2011
522011
Cu-mediated 1, 3-dipolar cycloaddition of azomethine ylides with dipolarophiles: a faster access to spirooxindoles of potential pharmacological interest
SN Singh, S Regati, AK Paul, M Layek, S Jayaprakash, KV Reddy, ...
Tetrahedron Letters 54 (40), 5448-5452, 2013
512013
AlCl (3) mediated unexpected migration of sulfonyl groups: regioselective synthesis of 7-sulfonyl indoles of potential pharmacological interest.
B Prasad, R Adepu, S Sandra, D Rambabu, GR Krishna, CM Reddy, ...
Chemical communications (Cambridge, England) 48, 10434-10436, 2012
492012
Spiro heterocycles as potential inhibitors of SIRT1: Pd/C-mediated synthesis of novel N-indolylmethyl spiroindoline-3, 2′-quinazolines
D Rambabu, G Raja, BY Sreenivas, GPK Seerapu, KL Kumar, GS Deora, ...
Bioorganic & medicinal chemistry letters 23 (5), 1351-1357, 2013
452013
Design, synthesis and biological evaluation of some novel 3-cinnamoyl-4-hydroxy-2H-chromen-2-ones as antimalarial agents
K Patel, C Karthikeyan, NS Hari Narayana Moorthy, GS Deora, ...
Medicinal Chemistry Research 21, 1780-1784, 2012
432012
Facile assembly of two 6-membered fused N-heterocyclic rings: a rapid access to novel small molecules via Cu-mediated reaction
MP R Adepu, R Sunke, CLT Meda, GS Deora, D Rambabu
Chemical Communications 49 (2), 190-192, 2013
412013
A brain-permeable inhibitor of the neurodegenerative disease target kynurenine 3-monooxygenase prevents accumulation of neurotoxic metabolites
S Zhang, M Sakuma, GS Deora, CW Levy, A Klausing, C Breda, KD Read, ...
Communications biology 2 (1), 271, 2019
402019
Effect of the Biphenyl Neolignan Honokiol on Aβ42-Induced Toxicity in Caenorhabditis elegans, Aβ42 Fibrillation, Cholinesterase Activity, DPPH Radicals, and …
S Kantham, S Chan, G McColl, JA Miles, SK Veliyath, GS Deora, ...
ACS Chemical Neuroscience 8 (9), 1901-1912, 2017
372017
Synthesis, anti-inflammatory, analgesic, COX1/2-inhibitory activity, and molecular docking studies of hybrid pyrazole analogues
MJ Alam, O Alam, SA Khan, MJ Naim, M Islamuddin, GS Deora
Drug design, development and therapy, 3529-3543, 2016
372016
Synthesis of 2, 2, 4-trimethyl-1, 2-dihydroquinolinyl substituted 1, 2, 3-triazole derivatives: Their evaluation as potential PDE 4B inhibitors possessing cytotoxic properties …
KSS Praveena, S Durgadas, NS Babu, S Akkenapally, CG Kumar, ...
Bioorganic Chemistry 53, 8-14, 2014
372014
Synthesis of novel benzimidazole acrylonitriles for inhibition of Plasmodium falciparum growth by dual target inhibition
K Sharma, A Shrivastava, RN Mehra, GS Deora, MM Alam, MS Zaman, ...
Archiv der Pharmazie 351 (1), 1700251, 2018
332018
Pyrrole [2, 3< i>-b</i>] quinoxalines as inhibitors of firefly luciferase: Their Cu-mediated synthesis and evaluation as false positives in a reporter Gene Assay
A Nakhi, S Rahman, R Kishore, CLT Meda, GS Deora, KVL Parsa, M Pal
Bioorganic & Medicinal Chemistry Letters 22, 6433-6441, 2012
322012
Multifunctional analogs of kynurenic acid for the treatment of Alzheimer’s disease: synthesis, pharmacology, and molecular modeling studies
GS Deora, S Kantham, S Chan, SN Dighe, SK Veliyath, G McColl, ...
ACS chemical neuroscience 8 (12), 2667-2675, 2017
312017
Design, synthesis and molecular modelling studies of novel 3-acetamido-4-methyl benzoic acid derivatives as inhibitors of protein tyrosine phosphatase 1B
M Rakse, C Karthikeyan, GS Deora, N Moorthy, V Rathore, AK Rawat, ...
European Journal of Medicinal Chemistry 70, 469-476, 2013
282013
Ligand/PTC-free intramolecular Heck reaction: synthesis of pyrroloquinoxalines and their evaluation against PDE4/luciferase/oral cancer cell growth in vitro and zebrafish in vivo
P Vijaya Babu, S Mukherjee, GS Deora, K Chennubhotla, R Medisetti, ...
Organic & biomolecular chemistry 11 (39), 6680-6685, 2013
282013
2, 3-Diaryl-3H-imidazo [4, 5-b] pyridine derivatives as potential anticancer and anti-inflammatory agents
EM Kirwen, T Batra, C Karthikeyan, GS Deora, V Rathore, C Mulakayala, ...
Acta Pharmaceutica Sinica B 7 (1), 73-79, 2017
272017
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