Lee-Yuan Liu-Chen
Lee-Yuan Liu-Chen
Temple University Lewis Katz School of Medicine
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Pharmacokinetics and pharmacodynamics of oral oxycodone in healthy human subjects: role of circulating active metabolites
B Lalovic, E Kharasch, C Hoffer, L Risler, LY Liu‐Chen, DD Shen
Clinical pharmacology & therapeutics 79 (5), 461-479, 2006
Comparison of pharmacological activities of buprenorphine and norbuprenorphine: norbuprenorphine is a potent opioid agonist
P Huang, GB Kehner, A Cowan, LY Liu-Chen
Journal of Pharmacology and Experimental Therapeutics 297 (2), 688-695, 2001
Molecular cloning and expression of a rat κ opioid receptor
S Li, J Zhu, C Chen, YW Chen, JK Deriel, B Ashby, LY Liu-Chen
Biochemical Journal 295 (3), 629-633, 1993
Comparison of pharmacological activities of three distinct κ ligands (salvinorin A, TRK-820 and 3FLB) on κ opioid receptors in vitro and their antipruritic and antinociceptive …
Y Wang, K Tang, S Inan, D Siebert, U Holzgrabe, DYW Lee, P Huang, ...
Journal of Pharmacology and Experimental Therapeutics 312 (1), 220-230, 2005
The association of NHERF adaptor proteins with G protein–coupled receptors and receptor tyrosine kinases
EJ Weinman, RA Hall, PA Friedman, LY Liu-Chen, S Shenolikar
Annu. Rev. Physiol. 68, 491-505, 2006
Immunohistochemical evidence for a substance P-containing trigeminovascular pathway to pial arteries in cats
LY Liu-Chen, MR Mayberg, MA Moskowitz
Brain research 268 (1), 162-166, 1983
Heterodimerization and cross-desensitization between the μ-opioid receptor and the chemokine CCR5 receptor
C Chen, J Li, G Bot, I Szabo, TJ Rogers, LY Liu-Chen
European journal of pharmacology 483 (2-3), 175-186, 2004
Mouse model of OPRM1 (A118G) polymorphism has sex-specific effects on drug-mediated behavior
SD Mague, C Isiegas, P Huang, LY Liu-Chen, C Lerman, JA Blendy
Proceedings of the National Academy of Sciences 106 (26), 10847-10852, 2009
U50, 488H-induced internalization of the human κ opioid receptor involves a β-arrestin-and dynamin-dependent mechanism: κ receptor internalization is not required for mitogen …
JG Li, LY Luo, JG Krupnick, JL Benovic, LY Liu-Chen
Journal of Biological Chemistry 274 (17), 12087-12094, 1999
Activation of the cloned human kappa opioid receptor by agonists enhances [35S] GTPγS binding to membranes: determination of potencies and efficacies of ligands
J Zhu, LY Luo, JG Li, C Chen, LY Liu-Chen
Journal of Pharmacology and Experimental Therapeutics 282 (2), 676-684, 1997
Differential binding domains of peptide and non-peptide ligands in the cloned rat kappa opioid receptor.
JC Xue, C Chen, J Zhu, S Kunapuli, JK DeRiel, L Yu, LY Liu-Chen
Journal of Biological Chemistry 269 (48), 30195-30199, 1994
In vitro release of immunoreactive substance P from putative afferent nerve endings in bovine pia arachnoid
MA Moskowitz, M Brody, LY Liu-Chen
Neuroscience 9 (4), 809-814, 1983
Mutational analysis of Gβγ and phospholipid interaction with G protein-coupled receptor kinase 2
CV Carman, LS Barak, C Chen, LY Liu-Chen, JJ Onorato, SP Kennedy, ...
Journal of Biological Chemistry 275 (14), 10443-10452, 2000
Cloning of a human κ opioid receptor from the brain
J Zhu, C Chen, JC Xue, S Kunapuli, JK DeRiel, LY Liu-Chen
Life sciences 56 (9), PL201-PL207, 1995
Dual ultrastructural immunocytochemical labeling of μ and δ opioid receptors in the superficial layers of the rat cervical spinal cord
PY Cheng, LY Liu-Chen, VM Pickel
Brain research 778 (2), 367-380, 1997
A common single nucleotide polymorphism A118G of the μ opioid receptor alters its N-glycosylation and protein stability
P Huang, C Chen, SD Mague, JA Blendy, LY Liu-Chen
Biochemical Journal 441 (1), 379-386, 2012
Ezrin-radixin-moesin-binding phosphoprotein-50/Na+/H+ exchanger regulatory factor (EBP50/NHERF) blocks U50, 488H-induced down-regulation of the human κ opioid receptor by …
JG Li, C Chen, LY Liu-Chen
Journal of Biological Chemistry 277 (30), 27545-27552, 2002
6′-Guanidinonaltrindole (6′-GNTI) is a G protein-biased κ-opioid receptor agonist that inhibits arrestin recruitment
ML Rives, M Rossillo, LY Liu-Chen, JA Javitch
Journal of Biological Chemistry 287 (32), 27050-27054, 2012
Agonist-induced regulation and trafficking of κ opioid receptors
LY Liu-Chen
Life sciences 75 (5), 511-536, 2004
Pia arachnoid contains substance P originating from trigeminal neurons
LY Liu-Chen, DH Han, MA Moskowitz
Neuroscience 9 (4), 803-808, 1983
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