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| Inositol Trisphosphate Receptor Ca2+ Release Channels JK Foskett, C White, KH Cheung, DOD Mak Physiological reviews 87 (2), 593-658, 2007 | 1401 | 2007 |
| Essential regulation of cell bioenergetics by constitutive InsP3 receptor Ca2+ transfer to mitochondria C Cárdenas, RA Miller, I Smith, T Bui, J Molgó, M Müller, H Vais, ... Cell 142 (2), 270-283, 2010 | 1096 | 2010 |
| Mechanism of Ca2+ disruption in Alzheimer's disease by presenilin regulation of InsP3 receptor channel gating KH Cheung, D Shineman, M Müller, C Cardenas, L Mei, J Yang, T Tomita, ... Neuron 58 (6), 871-883, 2008 | 526 | 2008 |
| Calcium signaling in Alzheimer's disease & therapies BCK Tong, AJ Wu, M Li, KH Cheung Biochimica et Biophysica Acta (BBA)-Molecular Cell Research 1865 (11), 1745-1760, 2018 | 236 | 2018 |
| Gain-of-function enhancement of IP3 receptor modal gating by familial Alzheimer’s disease–linked presenilin mutants in human cells and mouse neurons KH Cheung, L Mei, DOD Mak, I Hayashi, T Iwatsubo, DE Kang, JK Foskett Science signaling 3 (114), ra22-ra22, 2010 | 228 | 2010 |
| Balancing mTOR signaling and autophagy in the treatment of Parkinson’s disease Z Zhu, C Yang, A Iyaswamy, S Krishnamoorthi, SG Sreenivasmurthy, J Liu, ... International journal of molecular sciences 20 (3), 728, 2019 | 186 | 2019 |
| Calcium homeostasis modulator 1 (CALHM1) is the pore-forming subunit of an ion channel that mediates extracellular Ca2+ regulation of neuronal excitability Z Ma, AP Siebert, KH Cheung, RJ Lee, B Johnson, AS Cohen, ... Proceedings of the National Academy of Sciences 109 (28), E1963-E1971, 2012 | 163 | 2012 |
| A small molecule transcription factor EB activator ameliorates beta‐amyloid precursor protein and Tau pathology in Alzheimer's disease models JX Song, S Malampati, Y Zeng, SSK Durairajan, CB Yang, BCK Tong, ... Aging cell 19 (2), e13069, 2020 | 117 | 2020 |
| Vacuolin-1 potently and reversibly inhibits autophagosome-lysosome fusion by activating RAB5A Y Lu, S Dong, B Hao, C Li, K Zhu, W Guo, Q Wang, KH Cheung, ... Autophagy 10 (11), 1895-1905, 2014 | 112 | 2014 |
| Familial Alzheimer’s disease–associated presenilin 1 mutants promote γ-secretase cleavage of STIM1 to impair store-operated Ca2+ entry BCK Tong, CSK Lee, WH Cheng, KO Lai, J Kevin Foskett, KH Cheung Science signaling 9 (444), ra89-ra89, 2016 | 102 | 2016 |
| Constitutive cAMP response element binding protein (CREB) activation by Alzheimer's disease presenilin-driven inositol trisphosphate receptor (InsP3R) Ca2+ signaling M Müller, C Cárdenas, L Mei, KH Cheung, JK Foskett Proceedings of the National Academy of Sciences 108 (32), 13293-13298, 2011 | 96 | 2011 |
| Synergistic effects of cystic fibrosis transmembrane conductance regulator and aquaporin-9 in the rat epididymis KH Cheung, CT Leung, GPH Leung, PYD Wong Biology of reproduction 68 (5), 1505-1510, 2003 | 95 | 2003 |
| Regulation of epididymal principal cell functions by basal cells: role of transient receptor potential (Trp) proteins and cyclooxygenase-1 (COX-1) GPH Leung, KH Cheung, CT Leung, MW Tsang, PYD Wong Molecular and cellular endocrinology 216 (1-2), 5-13, 2004 | 86 | 2004 |
| Cell–cell interaction underlies formation of fluid in the male reproductive tract of the rat K Cheung, GPH Leung, MCT Leung, WWC Shum, W Zhou, PYD Wong The Journal of general physiology 125 (5), 443-454, 2005 | 82 | 2005 |
| Mechanistic study of TRPM2-Ca2+-CAMK2-BECN1 signaling in oxidative stress-induced autophagy inhibition Q Wang, W Guo, B Hao, X Shi, Y Lu, CWM Wong, VWS Ma, TTC Yip, ... Autophagy 12 (8), 1340-1354, 2016 | 75 | 2016 |
| Graded recruitment and inactivation of single InsP3 receptor Ca2+‐release channels: implications for quartal Ca2+ release L Ionescu, KH Cheung, H Vais, DOD Mak, C White, JK Foskett The Journal of physiology 573 (3), 645-662, 2006 | 75 | 2006 |
| Mode Switching Is the Major Mechanism of Ligand Regulation of InsP3 Receptor Calcium Release Channels L Ionescu, C White, KH Cheung, J Shuai, I Parker, JE Pearson, JK Foskett, ... The Journal of general physiology 130 (6), 631-645, 2007 | 69 | 2007 |
| Enhanced ROS generation mediated by Alzheimer's disease presenilin regulation of InsP3R Ca2+ signaling M Müller, KH Cheung, JK Foskett Antioxidants & redox signaling 14 (7), 1225-1235, 2011 | 65 | 2011 |
| Celastrol enhances transcription factor EB (TFEB)-mediated autophagy and mitigates Tau pathology: Implications for Alzheimer's disease therapy C Yang, C Su, A Iyaswamy, SK Krishnamoorthi, Z Zhu, S Yang, BC Tong, ... Acta Pharmaceutica Sinica B 12 (4), 1707-1722, 2022 | 59 | 2022 |
