| Metabolic profiling using stable isotope tracing reveals distinct patterns of glucose utilization by physiologically activated CD8+ T cells EH Ma, MJ Verway, RM Johnson, DG Roy, M Steadman, S Hayes, ... Immunity 51 (5), 856-870. e5, 2019 | 290 | 2019 |
| Methionine metabolism shapes T helper cell responses through regulation of epigenetic reprogramming DG Roy, J Chen, V Mamane, EH Ma, BM Muhire, RD Sheldon, ... Cell metabolism 31 (2), 250-266. e9, 2020 | 219 | 2020 |
| Impact of acute exposure to increased hydrostatic pressure and reduced shear rate on conduit artery endothelial function: a limb-specific response J Padilla, RD Sheldon, DM Sitar, SC Newcomer American Journal of Physiology-Heart and Circulatory Physiology 297 (3 …, 2009 | 132 | 2009 |
| Itaconate confers tolerance to late NLRP3 inflammasome activation M Bambouskova, L Potuckova, T Paulenda, M Kerndl, DA Mogilenko, ... Cell reports 34 (10), 2021 | 122 | 2021 |
| ER stress inhibits liver fatty acid oxidation while unmitigated stress leads to anorexia-induced lipolysis and both liver and kidney steatosis D DeZwaan-McCabe, RD Sheldon, MC Gorecki, DF Guo, ER Gansemer, ... Cell reports 19 (9), 1794-1806, 2017 | 89 | 2017 |
| The mitochondrial pyruvate carrier mediates high fat diet-induced increases in hepatic TCA cycle capacity AJ Rauckhorst, LR Gray, RD Sheldon, X Fu, AD Pewa, CR Feddersen, ... Molecular metabolism 6 (11), 1468-1479, 2017 | 76 | 2017 |
| Disrupting mitochondrial pyruvate uptake directs glutamine into the TCA cycle away from glutathione synthesis and impairs hepatocellular tumorigenesis SC Tompkins, RD Sheldon, AJ Rauckhorst, MF Noterman, SR Solst, ... Cell reports 28 (10), 2608-2619. e6, 2019 | 73 | 2019 |
| Aerobic exercise training in the treatment of non‐alcoholic fatty liver disease related fibrosis MA Linden, RD Sheldon, GM Meers, LC Ortinau, EM Morris, FW Booth, ... The Journal of physiology 594 (18), 5271-5284, 2016 | 67 | 2016 |
| Gestational exercise protects adult male offspring from high-fat diet-induced hepatic steatosis RD Sheldon, AN Blaize, JA Fletcher, KJ Pearson, SS Donkin, ... Journal of hepatology 64 (1), 171-178, 2016 | 61 | 2016 |
| Impaired skeletal muscle mitochondrial pyruvate uptake rewires glucose metabolism to drive whole-body leanness A Sharma, L Oonthonpan, RD Sheldon, AJ Rauckhorst, Z Zhu, ... Elife 8, e45873, 2019 | 59 | 2019 |
| Carbon source availability drives nutrient utilization in CD8+ T cells I Kaymak, KM Luda, LR Duimstra, EH Ma, J Longo, MS Dahabieh, ... Cell metabolism 34 (9), 1298-1311. e6, 2022 | 57 | 2022 |
| Acute impact of intermittent pneumatic leg compression frequency on limb hemodynamics, vascular function, and skeletal muscle gene expression in humans RD Sheldon, BT Roseguini, JP Thyfault, BD Crist, MH Laughlin, ... Journal of Applied Physiology 112 (12), 2099-2109, 2012 | 54 | 2012 |
| 1-Methylnicotinamide is an immune regulatory metabolite in human ovarian cancer MK Kilgour, S MacPherson, LG Zacharias, AE Ellis, RD Sheldon, EY Liu, ... Science Advances 7 (4), eabe1174, 2021 | 52 | 2021 |
| New insights into the physiologic basis for intermittent pneumatic limb compression as a therapeutic strategy for peripheral artery disease RD Sheldon, BT Roseguini, MH Laughlin, SC Newcomer Journal of vascular surgery 58 (6), 1688-1696, 2013 | 49 | 2013 |
| Structure of an AMPK complex in an inactive, ATP-bound state Y Yan, S Mukherjee, KG Harikumar, TS Strutzenberg, XE Zhou, ... Science 373 (6553), 413-419, 2021 | 48 | 2021 |
| eNOS deletion impairs mitochondrial quality control and exacerbates Western diet-induced NASH RD Sheldon, GM Meers, EM Morris, MA Linden, RP Cunningham, ... American Journal of Physiology-Endocrinology and Metabolism 317 (4), E605-E616, 2019 | 43 | 2019 |
| Chronic NOS inhibition accelerates NAFLD progression in an obese rat model RD Sheldon, J Padilla, NT Jenkins, MH Laughlin, RS Rector American Journal of Physiology-Gastrointestinal and Liver Physiology 308 (6 …, 2015 | 41 | 2015 |
| Oxaloacetic acid mediates ADP-dependent inhibition of mitochondrial complex II–driven respiration BD Fink, F Bai, L Yu, RD Sheldon, A Sharma, EB Taylor, WI Sivitz Journal of Biological Chemistry 293 (51), 19932-19941, 2018 | 40 | 2018 |
| Fibroblast growth factor 21 and exercise-induced hepatic mitochondrial adaptations JA Fletcher, MA Linden, RD Sheldon, GM Meers, EM Morris, A Butterfield, ... American Journal of Physiology-Gastrointestinal and Liver Physiology 310 (10 …, 2016 | 36 | 2016 |
| Reduced hepatic eNOS phosphorylation is associated with NAFLD and type 2 diabetes progression and is prevented by daily exercise in hyperphagic OLETF rats RD Sheldon, MH Laughlin, RS Rector Journal of Applied Physiology 116 (9), 1156-1164, 2014 | 36 | 2014 |
