Frank A. Kruyt
Frank A. Kruyt
Professor of Experimental Oncology
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Cell death independent of caspases: a review
LE Broker, FAE Kruyt, G Giaccone
Clinical Cancer Research 11 (9), 3155-3162, 2005
Expression cloning of a cDNA for the major Fanconi anaemia gene, FAA
JR Lo Ten Foe, MA Rooimans, L Bosnoyan-Collins, N Alon, M Wijker, ...
Nature genetics 14 (3), 320-323, 1996
Response to epidermal growth factor receptor inhibitors in non-small cell lung cancer cells: limited antiproliferative effects and absence of apoptosis associated with …
ML Janmaat, FAE Kruyt, JA Rodriguez, G Giaccone
Clinical Cancer Research 9 (6), 2316-2326, 2003
Apoptosis: target of cancer therapy
CG Ferreira, M Epping, FAE Kruyt, G Giaccone
Clinical Cancer Research 8 (7), 2024-2034, 2002
Global histone modifications predict prognosis of resected non–small-cell lung cancer
F Barlési, G Giaccone, MI Gallegos-Ruiz, A Loundou, SW Span, ...
Journal of clinical oncology 25 (28), 4358-4364, 2007
Hypoxia enhances migration and invasion in glioblastoma by promoting a mesenchymal shift mediated by the HIF1α–ZEB1 axis
JV Joseph, S Conroy, K Pavlov, P Sontakke, T Tomar, E Eggens-Meijer, ...
Cancer letters 359 (1), 107-116, 2015
Cathepsin B mediates caspase-independent cell death induced by microtubule stabilizing agents in non-small cell lung cancer cells
LE Bröker, C Huisman, SW Span, JA Rodriguez, FAE Kruyt, G Giaccone
Cancer research 64 (1), 27-30, 2004
Circulating tumor cells in small-cell lung cancer: a predictive and prognostic factor
TJN Hiltermann, MM Pore, A van den Berg, W Timens, HM Boezen, ...
Annals of oncology 23 (11), 2937-2942, 2012
Chemotherapy triggers apoptosis in a caspase-8-dependent and mitochondria-controlled manner in the non-small cell lung cancer cell line NCI-H460
CG Ferreira, SW Span, GJ Peters, FAE Kruyt, G Giaccone
Cancer research 60 (24), 7133-7141, 2000
CRM1-mediated nuclear export determines the cytoplasmic localization of the antiapoptotic protein Survivin
JA Rodríguez, SW Span, CGM Ferreira, FAE Kruyt, G Giaccone
Experimental cell research 275 (1), 44-53, 2002
The Fanconi anemia protein FANCF forms a nuclear complex with FANCA, FANCC and FANCG
JP De Winter, L Van Der Weel, J De Groot, S Stone, Q Waisfisz, F Arwert, ...
Human Molecular Genetics 9 (18), 2665-2674, 2000
Playing the DISC: turning on TRAIL death receptor-mediated apoptosis in cancer
B Pennarun, A Meijer, EGE de Vries, JH Kleibeuker, F Kruyt, S de Jong
Biochimica et Biophysica Acta (BBA)-Reviews on Cancer 1805 (2), 123-140, 2010
TRAIL and cancer therapy
FAE Kruyt
Cancer letters 263 (1), 14-25, 2008
Non-canonical kinase signaling by the death ligand TRAIL in cancer cells: discord in the death receptor family
K Azijli, B Weyhenmeyer, GJ Peters, S De Jong, FAE Kruyt
Cell Death & Differentiation 20 (7), 858-868, 2013
TGF-β is an inducer of ZEB1-dependent mesenchymal transdifferentiation in glioblastoma that is associated with tumor invasion
JV Joseph, S Conroy, T Tomar, E Eggens-Meijer, K Bhat, S Copray, ...
Cell death & disease 5 (10), e1443-e1443, 2014
TGF-β as a therapeutic target in high grade gliomas–promises and challenges
JV Joseph, V Balasubramaniyan, A Walenkamp, FAE Kruyt
Biochemical pharmacology 85 (4), 478-485, 2013
Abnormal microsomal detoxification implicated in Fanconi anemia group C by interaction of the FAC protein with NADPH cytochrome P450 reductase
FAE Kruyt, T Hoshino, JM Liu, P Joseph, AK Jaiswal, H Youssoufian
Blood, The Journal of the American Society of Hematology 92 (9), 3050-3056, 1998
Enhanced cytotoxicity induced by gefitinib and specific inhibitors of the Ras or phosphatidyl inositol‐3 kinase pathways in non‐small cell lung cancer cells
ML Janmaat, JA Rodriguez, M Gallegos‐Ruiz, FAE Kruyt, G Giaccone
International journal of cancer 118 (1), 209-214, 2006
Expression of X-linked inhibitor of apoptosis as a novel prognostic marker in radically resected non-small cell lung cancer patients
CG Ferreira, P van der Valk, SW Span, I Ludwig, EF Smit, FAE Kruyt, ...
Clinical cancer research 7 (8), 2468-2474, 2001
A physical complex of the Fanconi anemia proteins FANCG/XRCC9 and FANCA
Q Waisfisz, JP De Winter, FAE Kruyt, J De Groot, L Van Der Weel, ...
Proceedings of the National Academy of Sciences 96 (18), 10320-10325, 1999
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