Synthesis and in vitro anticancer activity of certain novel 1-(2-methyl-6-arylpyridin-3-yl)-3-phenylureas as apoptosis-inducing agents WM Eldehna, GS Hassan, ST Al-Rashood, T Al-Warhi, AE Altyar, ... Journal of enzyme inhibition and medicinal chemistry 34 (1), 322-332, 2019 | 76 | 2019 |
Interaction of an abiraterone with calf thymus DNA: Investigation with spectroscopic technique and modelling studies TA Wani, N Alsaif, AH Bakheit, S Zargar, AA Al-Mehizia, AA Khan Bioorganic Chemistry 100, 103957, 2020 | 75 | 2020 |
Tumor-associated carbonic anhydrase isoform IX and XII inhibitory properties of certain isatin-bearing sulfonamides endowed with in vitro antitumor activity towards colon cancer WM Eldehna, A Nocentini, ST Al-Rashood, GS Hassan, HM Alkahtani, ... Bioorganic Chemistry 81, 425-432, 2018 | 68 | 2018 |
Antitumor properties of certain spirooxindoles towards hepatocellular carcinoma endowed with antioxidant activity ST Al-Rashood, AR Hamed, GS Hassan, HM Alkahtani, AA Almehizia, ... Journal of Enzyme Inhibition and Medicinal Chemistry 35 (1), 831-839, 2020 | 64 | 2020 |
Design, synthesis and molecular docking of new pyrazole-thiazolidinones as potent anti-inflammatory and analgesic agents with TNF-α inhibitory activity SS Abd El-Karim, HS Mohamed, MF Abdelhameed, AEGE Amr, ... Bioorganic chemistry 111, 104827, 2021 | 62 | 2021 |
Discovery of new Schiff bases tethered pyrazole moiety: Design, synthesis, biological evaluation, and molecular docking study as dual targeting DHFR/DNA gyrase inhibitors with … AS Hassan, AA Askar, AM Naglah, AA Almehizia, A Ragab Molecules 25 (11), 2593, 2020 | 60 | 2020 |
Lead Discovery, Chemistry Optimization, and Biological Evaluation Studies of Novel Biamide Derivatives as CB2 Receptor Inverse Agonists and Osteoclast Inhibitors P Yang, KZ Myint, Q Tong, R Feng, H Cao, AA Almehizia, MH Alqarni, ... Journal of medicinal chemistry 55 (22), 9973-9987, 2012 | 60 | 2012 |
SLC-0111 enaminone analogs, 3/4-(3-aryl-3-oxopropenyl) aminobenzenesulfonamides, as novel selective subnanomolar inhibitors of the tumor-associated carbonic anhydrase isoform IX WM Eldehna, MF Abo-Ashour, E Berrino, D Vullo, HA Ghabbour, ... Bioorganic chemistry 83, 549-558, 2019 | 57 | 2019 |
Novel triaryl sulfonamide derivatives as selective cannabinoid receptor 2 inverse agonists and osteoclast inhibitors: discovery, optimization, and biological evaluation P Yang, L Wang, R Feng, AA Almehizia, Q Tong, KZ Myint, Q Ouyang, ... Journal of medicinal chemistry 56 (5), 2045-2058, 2013 | 50 | 2013 |
Synthesis, cytotoxic evaluation, and molecular docking studies of novel quinazoline derivatives with benzenesulfonamide and anilide tails: Dual inhibitors of EGFR/HER2 HM Alkahtani, AN Abdalla, AJ Obaidullah, MM Alanazi, AA Almehizia, ... Bioorganic Chemistry 95, 103461, 2020 | 48 | 2020 |
A spectroscopic, thermodynamic and molecular docking study of the binding mechanism of dapoxetine with calf thymus DNA NA Alsaif, AA Al-Mehiziaa, AH Bakheit, S Zargar, TA Wani South African Journal of Chemistry 73 (1), 44–50-44–50, 2020 | 43 | 2020 |
Synthesis, anticancer, apoptosis-inducing activities and EGFR and VEGFR2 assay mechanistic studies of 5, 5-diphenylimidazolidine-2, 4-dione derivatives: Molecular docking studies HM Alkahtani, MM Alanazi, FS Aleanizy, FY Alqahtani, A Alhoshani, ... Saudi Pharmaceutical Journal 27 (5), 682-693, 2019 | 42 | 2019 |
Synthesis of novel isoindoline-1, 3-dione-based oximes and benzenesulfonamide hydrazones as selective inhibitors of the tumor-associated carbonic anhydrase IX AM Alaa, AS El-Azab, MAA El-Enin, AA Almehizia, CT Supuran, ... Bioorganic Chemistry 80, 706-713, 2018 | 41 | 2018 |
Mechanistic interaction study of 5, 6-Dichloro-2-[2-(pyridin-2-yl) ethyl] isoindoline-1, 3-dione with bovine serum albumin by spectroscopic and molecular docking approaches MM Alanazi, AA Almehizia, AH Bakheit, NA Alsaif, HM Alkahtani, TA Wani Saudi Pharmaceutical Journal 27 (3), 341-347, 2019 | 40 | 2019 |
Facile synthesis and characterization of ZnO nanoparticles for studying their biological activities and photocatalytic degradation properties toward methylene blue dye AA Almehizia, MA Al-Omar, AM Naglah, MA Bhat, NS Al-Shakliah Alexandria Engineering Journal 61 (3), 2386-2395, 2022 | 39 | 2022 |
Antioxidant activities and molecular docking of 2-thioxobenzo[g]quinazoline derivatives R Al-Salahi, HAA Taie, AH Bakheit, M Marzouk, AA Almehizia, R Herqash, ... Pharmacological Reports 71, 695-700, 2019 | 37 | 2019 |
Novel Carbon/PEDOT/PSS-Based screen-printed biosensors for acetylcholine neurotransmitter and acetylcholinesterase detection in human serum NH Ashmawy, AA Almehizia, TA Youssef, AEGE Amr, MA Al-Omar, ... Molecules 24 (8), 1539, 2019 | 37 | 2019 |
Targeting microbial resistance: Synthesis, antibacterial evaluation, DNA binding and modeling study of new chalcone-based dithiocarbamate derivatives M Ayman, SM El-Messery, EE Habib, ST Al-Rashood, AA Almehizia, ... Bioorganic Chemistry 85, 282-292, 2019 | 36 | 2019 |
Design and activity of AP endonuclease-1 inhibitors Z Feng, S Kochanek, D Close, LR Wang, A Srinivasan, AA Almehizia, ... Journal of chemical biology 8, 79-93, 2015 | 32 | 2015 |
Immunoinformatics-guided design of a multi-epitope vaccine based on the structural proteins of severe acute respiratory syndrome coronavirus 2 AJ Obaidullah, MM Alanazi, NA Alsaif, H Albassam, AA Almehizia, ... RSC advances 11 (29), 18103-18121, 2021 | 29 | 2021 |