Tuan Zea Tan
Tuan Zea Tan
Cancer Science Institute of Singapore
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Epithelial‐mesenchymal transition spectrum quantification and its efficacy in deciphering survival and drug responses of cancer patients
TZ Tan, QH Miow, Y Miki, T Noda, S Mori, RYJ Huang, JP Thiery
EMBO molecular medicine 6 (10), 1279-1293, 2014
An EMT spectrum defines an anoikis-resistant and spheroidogenic intermediate mesenchymal state that is sensitive to e-cadherin restoration by a src-kinase inhibitor …
RYJ Huang, MK Wong, TZ Tan, KT Kuay, AHC Ng, VY Chung, YS Chu, ...
Cell death & disease 4 (11), e915-e915, 2013
Dual role of autophagy in hallmarks of cancer
SS Singh, S Vats, AYQ Chia, TZ Tan, S Deng, MS Ong, F Arfuso, CT Yap, ...
Oncogene 37 (9), 1142-1158, 2018
Epithelial-to-mesenchymal transition and autophagy induction in breast carcinoma promote escape from T-cell–mediated lysis
I Akalay, B Janji, M Hasmim, MZ Noman, F André, P De Cremoux, ...
Cancer research 73 (8), 2418-2427, 2013
Lgr5 marks stem/progenitor cells in ovary and tubal epithelia
A Ng, S Tan, G Singh, P Rizk, Y Swathi, TZ Tan, RYJ Huang, ...
Nature cell biology 16 (8), 745-757, 2014
Molecular subtypes of urothelial bladder cancer: results from a meta-cohort analysis of 2411 tumors
TZ Tan, M Rouanne, KT Tan, RYJ Huang, JP Thiery
European urology 75 (3), 423-432, 2019
The immune checkpoint ligand PD-L1 is upregulated in EMT-activated human breast cancer cells by a mechanism involving ZEB-1 and miR-200
MZ Noman, B Janji, A Abdou, M Hasmim, S Terry, TZ Tan, ...
Oncoimmunology 6 (1), e1263412, 2017
Functional genomics identifies five distinct molecular subtypes with clinical relevance and pathways for growth control in epithelial ovarian cancer
TZ Tan, QH Miow, RYJ Huang, MK Wong, J Ye, JA Lau, MC Wu, ...
EMBO molecular medicine 5 (7), 1051-1066, 2013
Short-term expansion of breast circulating cancer cells predicts response to anti-cancer therapy
BL Khoo, SC Lee, P Kumar, TZ Tan, ME Warkiani, SGW Ow, S Nandi, ...
Oncotarget 6 (17), 15578, 2015
Molecular characterization of breast cancer CTCs associated with brain metastasis
D Boral, M Vishnoi, HN Liu, W Yin, ML Sprouse, A Scamardo, DS Hong, ...
Nature communications 8 (1), 1-10, 2017
A novel cognitive interpretation of breast cancer thermography with complementary learning fuzzy neural memory structure
TZ Tan, C Quek, GS Ng, EYK Ng
Expert Systems with Applications 33 (3), 652-666, 2007
DEAD-box helicase DP103 defines metastatic potential of human breast cancers
EM Shin, HS Hay, MH Lee, JN Goh, TZ Tan, YP Sen, SW Lim, EM Yousef, ...
The Journal of clinical investigation 124 (9), 3807-3824, 2014
FZD7 drives in vitro aggressiveness in Stem-A subtype of ovarian cancer via regulation of non-canonical Wnt/PCP pathway
M Asad, MK Wong, TZ Tan, M Choolani, J Low, S Mori, D Virshup, ...
Cell death & disease 5 (7), e1346-e1346, 2014
GRHL2-miR-200-ZEB1 maintains the epithelial status of ovarian cancer through transcriptional regulation and histone modification
VY Chung, TZ Tan, M Tan, MK Wong, KT Kuay, Z Yang, J Ye, J Muller, ...
Scientific reports 6 (1), 1-15, 2016
Epithelial–mesenchymal status renders differential responses to cisplatin in ovarian cancer
QH Miow, TZ Tan, J Ye, JA Lau, T Yokomizo, JP Thiery, S Mori
Oncogene 34 (15), 1899-1907, 2015
TRPV4 regulates breast cancer cell extravasation, stiffness and actin cortex
WH Lee, LY Choong, NN Mon, SY Lu, Q Lin, B Pang, B Yan, VSR Krishna, ...
Scientific reports 6 (1), 1-16, 2016
The GAS6-AXL signaling network is a mesenchymal (Mes) molecular subtype–specific therapeutic target for ovarian cancer
J Antony, TZ Tan, Z Kelly, J Low, M Choolani, C Recchi, H Gabra, ...
Science Signaling 9 (448), ra97-ra97, 2016
Disruption of Runx1 and Runx3 leads to bone marrow failure and leukemia predisposition due to transcriptional and DNA repair defects
CQ Wang, V Krishnan, LS Tay, DWL Chin, CP Koh, JY Chooi, GSS Nah, ...
Cell reports 8 (3), 767-782, 2014
A COL11A1-correlated pan-cancer gene signature of activated fibroblasts for the prioritization of therapeutic targets
D Jia, Z Liu, N Deng, TZ Tan, RYJ Huang, B Taylor-Harding, DJ Cheon, ...
Cancer letters 382 (2), 203-214, 2016
SPHK1 regulates proliferation and survival responses in triple-negative breast cancer
A Datta, SY Loo, B Huang, L Wong, SSL Tan, TZ Tan, SC Lee, JP Thiery, ...
Oncotarget 5 (15), 5920, 2014
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