|Epithelial‐mesenchymal transition spectrum quantification and its efficacy in deciphering survival and drug responses of cancer patients|
TZ Tan, QH Miow, Y Miki, T Noda, S Mori, RYJ Huang, JP Thiery
EMBO molecular medicine 6 (10), 1279-1293, 2014
|An EMT spectrum defines an anoikis-resistant and spheroidogenic intermediate mesenchymal state that is sensitive to e-cadherin restoration by a src-kinase inhibitor …|
RYJ Huang, MK Wong, TZ Tan, KT Kuay, AHC Ng, VY Chung, YS Chu, ...
Cell death & disease 4 (11), e915-e915, 2013
|Epithelial-to-mesenchymal transition and autophagy induction in breast carcinoma promote escape from T-cell–mediated lysis|
I Akalay, B Janji, M Hasmim, MZ Noman, F André, P De Cremoux, ...
Cancer research 73 (8), 2418-2427, 2013
|Dual role of autophagy in hallmarks of cancer|
SS Singh, S Vats, AYQ Chia, TZ Tan, S Deng, MS Ong, F Arfuso, CT Yap, ...
Oncogene 37 (9), 1142-1158, 2018
|Functional genomics identifies five distinct molecular subtypes with clinical relevance and pathways for growth control in epithelial ovarian cancer|
TZ Tan, QH Miow, RYJ Huang, MK Wong, J Ye, JA Lau, MC Wu, ...
EMBO molecular medicine 5 (7), 1051-1066, 2013
|Lgr5 marks stem/progenitor cells in ovary and tubal epithelia|
A Ng, S Tan, G Singh, P Rizk, Y Swathi, TZ Tan, RYJ Huang, ...
Nature cell biology 16 (8), 745-757, 2014
|A novel cognitive interpretation of breast cancer thermography with complementary learning fuzzy neural memory structure|
TZ Tan, C Quek, GS Ng, EYK Ng
Expert Systems with Applications 33 (3), 652-666, 2007
|Short-term expansion of breast circulating cancer cells predicts response to anti-cancer therapy|
BL Khoo, SC Lee, P Kumar, TZ Tan, ME Warkiani, SGW Ow, S Nandi, ...
Oncotarget 6 (17), 15578, 2015
|DEAD-box helicase DP103 defines metastatic potential of human breast cancers|
EM Shin, HS Hay, MH Lee, JN Goh, TZ Tan, YP Sen, SW Lim, EM Yousef, ...
The Journal of clinical investigation 124 (9), 3807-3824, 2014
|FZD7 drives in vitro aggressiveness in Stem-A subtype of ovarian cancer via regulation of non-canonical Wnt/PCP pathway|
M Asad, MK Wong, TZ Tan, M Choolani, J Low, S Mori, D Virshup, ...
Cell death & disease 5 (7), e1346-e1346, 2014
|Epithelial–mesenchymal status renders differential responses to cisplatin in ovarian cancer|
QH Miow, TZ Tan, J Ye, JA Lau, T Yokomizo, JP Thiery, S Mori
Oncogene 34 (15), 1899-1907, 2015
|The immune checkpoint ligand PD-L1 is upregulated in EMT-activated human breast cancer cells by a mechanism involving ZEB-1 and miR-200|
MZ Noman, B Janji, A Abdou, M Hasmim, S Terry, TZ Tan, ...
Oncoimmunology 6 (1), e1263412, 2017
|GRHL2-miR-200-ZEB1 maintains the epithelial status of ovarian cancer through transcriptional regulation and histone modification|
VY Chung, TZ Tan, M Tan, MK Wong, KT Kuay, Z Yang, J Ye, J Muller, ...
Scientific reports 6 (1), 1-15, 2016
|Disruption of Runx1 and Runx3 leads to bone marrow failure and leukemia predisposition due to transcriptional and DNA repair defects|
CQ Wang, V Krishnan, LS Tay, DWL Chin, CP Koh, JY Chooi, GSS Nah, ...
Cell reports 8 (3), 767-782, 2014
|Molecular characterization of breast cancer CTCs associated with brain metastasis|
D Boral, M Vishnoi, HN Liu, W Yin, ML Sprouse, A Scamardo, DS Hong, ...
Nature communications 8 (1), 1-10, 2017
|Ovarian cancer diagnosis with complementary learning fuzzy neural network|
TZ Tan, C Quek, GS Ng, K Razvi
Artificial intelligence in medicine 43 (3), 207-222, 2008
|Brain-inspired genetic complementary learning for stock market prediction|
TZ Tan, C Quek, GS Ng
2005 IEEE Congress on Evolutionary Computation 3, 2653-2660, 2005
|SPHK1 regulates proliferation and survival responses in triple-negative breast cancer|
A Datta, SY Loo, B Huang, L Wong, SSL Tan, TZ Tan, SC Lee, JP Thiery, ...
Oncotarget 5 (15), 5920, 2014
|Molecular subtypes of urothelial bladder cancer: results from a meta-cohort analysis of 2411 tumors|
TZ Tan, M Rouanne, KT Tan, RYJ Huang, JP Thiery
European urology 75 (3), 423-432, 2019
|The GAS6-AXL signaling network is a mesenchymal (Mes) molecular subtype–specific therapeutic target for ovarian cancer|
J Antony, TZ Tan, Z Kelly, J Low, M Choolani, C Recchi, H Gabra, ...
Sci. Signal. 9 (448), ra97-ra97, 2016