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emma wincent
emma wincent
Senior research fellow at Karolinska Institutet, Institute of Environmental Medicine
Verified email at ki.se
Title
Cited by
Cited by
Year
Feedback control of AHR signalling regulates intestinal immunity
C Schiering, E Wincent, A Metidji, A Iseppon, Y Li, AJ Potocnik, ...
Nature 542 (7640), 242-245, 2017
4332017
The suggested physiologic aryl hydrocarbon receptor activator and cytochrome P4501 substrate 6-formylindolo [3, 2-b] carbazole is present in humans
E Wincent, N Amini, S Luecke, H Glatt, J Bergman, C Crescenzi, ...
Journal of biological chemistry 284 (5), 2690-2696, 2009
3322009
Inhibition of cytochrome P4501-dependent clearance of the endogenous agonist FICZ as a mechanism for activation of the aryl hydrocarbon receptor
E Wincent, J Bengtsson, AM Bardbori, T Alsberg, S Luecke, U Rannug, ...
Proceedings of the National Academy of Sciences 109 (12), 4479-4484, 2012
2232012
AHR in the intestinal microenvironment: safeguarding barrier function
B Stockinger, K Shah, E Wincent
Nature reviews Gastroenterology & hepatology 18 (8), 559-570, 2021
1732021
Quercetin, resveratrol, and curcumin are indirect activators of the aryl hydrocarbon receptor (AHR)
A Mohammadi-Bardbori, J Bengtsson, U Rannug, A Rannug, E Wincent
Chemical research in toxicology 25 (9), 1878-1884, 2012
1692012
Evidence for new light-independent pathways for generation of the endogenous aryl hydrocarbon receptor agonist FICZ
A Smirnova, E Wincent, L Vikström Bergander, T Alsberg, J Bergman, ...
Chemical research in toxicology 29 (1), 75-86, 2016
1192016
Metabolic fate of the Ah receptor ligand 6-formylindolo [3, 2-b] carbazole
L Bergander, E Wincent, A Rannug, M Foroozesh, W Alworth, U Rannug
Chemico-biological interactions 149 (2-3), 151-164, 2004
1132004
Aryl hydrocarbon receptor activation and developmental toxicity in zebrafish in response to soil extracts containing unsubstituted and oxygenated PAHs
E Wincent, ME Jonsson, M Bottai, S Lundstedt, K Dreij
Environmental science & technology 49 (6), 3869-3877, 2015
932015
Toxicokinetics of Perfluorinated Alkyl Acids Influences Their Toxic Potency in the Zebrafish Embryo (Danio rerio)
C Vogs, G Johanson, M Näslund, S Wulff, M Sjödin, M Hellstrandh, ...
Environmental science & technology 53 (7), 3898-3907, 2019
812019
Cellular accumulation and lipid binding of perfluorinated alkylated substances (PFASs)–A comparison with lysosomotropic drugs
DS Garcia, M Sjödin, M Hellstrandh, U Norinder, V Nikiforova, J Lindberg, ...
Chemico-biological interactions 281, 1-10, 2018
602018
Biological effects of 6-formylindolo [3, 2-b] carbazole (FICZ) in vivo are enhanced by loss of CYP1A function in an Ahr2-dependent manner
E Wincent, A Kubota, A Timme-Laragy, ME Jönsson, ME Hahn, ...
Biochemical pharmacology 110, 117-129, 2016
512016
Synthesis and biological evaluation of fused thio-and selenopyrans as new indolocarbazole analogues with aryl hydrocarbon receptor affinity
E Wincent, H Shirani, J Bergman, U Rannug, T Janosik
Bioorganic & medicinal chemistry 17 (4), 1648-1653, 2009
432009
Cytochrome P4501-inhibiting chemicals amplify aryl hydrocarbon receptor activation and IL-22 production in T helper 17 cells
C Schiering, A Vonk, S Das, B Stockinger, E Wincent
Biochemical pharmacology 151, 47-58, 2018
402018
Induction and inhibition of human cytochrome P4501 by oxygenated polycyclic aromatic hydrocarbons
E Wincent, F Le Bihanic, K Dreij
Toxicology Research 5 (3), 788-799, 2016
402016
Cytochrome P450 1A1 gene regulation by UVB involves crosstalk between the aryl hydrocarbon receptor and nuclear factor κB
S Luecke, E Wincent, M Backlund, U Rannug, A Rannug
Chemico-biological interactions 184 (3), 466-473, 2010
402010
Combination effects of AHR agonists and Wnt/β-catenin modulators in zebrafish embryos: implications for physiological and toxicological AHR functions
E Wincent, JJ Stegeman, ME Jönsson
Toxicology and applied pharmacology 284 (2), 163-179, 2015
272015
Retene, pyrene and phenanthrene cause distinct molecular-level changes in the cardiac tissue of rainbow trout (Oncorhynchus mykiss) larvae, part 2–Proteomics and metabolomics
C Rigaud, A Eriksson, A Rokka, M Skaugen, J Lihavainen, M Keinänen, ...
Science of The Total Environment 746, 141161, 2020
262020
Exposure to retene, fluoranthene, and their binary mixture causes distinct transcriptomic and apical outcomes in rainbow trout (Oncorhynchus mykiss) yolk sac alevins
ANM Eriksson, C Rigaud, A Krasnov, E Wincent, ER Vehniäinen
Aquatic Toxicology 244, 106083, 2022
112022
Perfluorooctanesulfonic acid modulates barrier function and systemic T-cell homeostasis during intestinal inflammation
OE Diaz, C Sorini, RA Morales, X Luo, A Frede, AM Krais, MN Chávez, ...
Disease models & mechanisms 14 (12), dmm049104, 2021
102021
Non-additive mixture effects of benzo [a] pyrene and pesticides in vitro and in vivo: Role of AhR signaling
BÜ Endirlik, E Wincent, K Dreij
Environmental Pollution 316, 120510, 2023
72023
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