| Membrane potential modulates plasma membrane phospholipid dynamics and K-Ras signaling Y Zhou, CO Wong, K Cho, D Van Der Hoeven, H Liang, DP Thakur, J Luo, ... Science 349 (6250), 873-876, 2015 | 261 | 2015 |
| Inhibition of RAS function through targeting an allosteric regulatory site R Spencer-Smith, A Koide, Y Zhou, RR Eguchi, F Sha, P Gajwani, ... Nature chemical biology 13 (1), 62-68, 2017 | 237 | 2017 |
| Lipid-sorting specificity encoded in K-Ras membrane anchor regulates signal output Y Zhou, P Prakash, H Liang, KJ Cho, AA Gorfe, JF Hancock Cell 168 (1-2), 239-251. e16, 2017 | 229 | 2017 |
| Ras nanoclusters: Versatile lipid-based signaling platforms Y Zhou, JF Hancock Biochimica et Biophysica Acta (BBA)-Molecular Cell Research 1853 (4), 841-849, 2015 | 224 | 2015 |
| Tumor induces muscle wasting in mice through releasing extracellular Hsp70 and Hsp90 G Zhang, Z Liu, H Ding, Y Zhou, HA Doan, KWT Sin, ZJ Zhu, R Flores, ... Nature communications 8 (1), 589, 2017 | 182 | 2017 |
| NSAID injury to the gastrointestinal tract: evidence that NSAIDs interact with phospholipids to weaken the hydrophobic surface barrier and induce the formation of unstable … LM Lichtenberger, Y Zhou, EJ Dial, RM Raphael Journal of pharmacy and pharmacology 58 (11), 1421-1428, 2006 | 169 | 2006 |
| Insight into NSAID-induced membrane alterations, pathogenesis and therapeutics: characterization of interaction of NSAIDs with phosphatidylcholine LM Lichtenberger, Y Zhou, V Jayaraman, JR Doyen, RG O'Neil, EJ Dial, ... Biochimica et Biophysica Acta (BBA)-Molecular and Cell Biology of Lipids …, 2012 | 143 | 2012 |
| Signal integration by lipid-mediated spatial cross talk between Ras nanoclusters Y Zhou, H Liang, T Rodkey, N Ariotti, RG Parton, JF Hancock Molecular and cellular biology 34 (5), 862-876, 2014 | 138 | 2014 |
| Single-molecule analysis reveals self assembly and nanoscale segregation of two distinct cavin subcomplexes on caveolae Y Gambin, N Ariotti, KA McMahon, M Bastiani, E Sierecki, O Kovtun, ... elife 3, e01434, 2014 | 138 | 2014 |
| Solution pH alters mechanical and electrical properties of phosphatidylcholine membranes: relation between interfacial electrostatics, intramembrane potential, and bending … Y Zhou, RM Raphael Biophysical journal 92 (7), 2451-2462, 2007 | 138 | 2007 |
| Caveolae regulate the nanoscale organization of the plasma membrane to remotely control Ras signaling N Ariotti, MA Fernández-Rojo, Y Zhou, MM Hill, TL Rodkey, KL Inder, ... Journal of Cell Biology 204 (5), 777-792, 2014 | 132 | 2014 |
| Oncogenic K-Ras binds to an anionic membrane in two distinct orientations: a molecular dynamics analysis P Prakash, Y Zhou, H Liang, JF Hancock, AA Gorfe Biophysical journal 110 (5), 1125-1138, 2016 | 119 | 2016 |
| ω-3 polyunsaturated fatty acids direct differentiation of the membrane phenotype in mesenchymal stem cells to potentiate osteogenesis KR Levental, MA Surma, AD Skinkle, JH Lorent, Y Zhou, C Klose, ... Science advances 3 (11), eaao1193, 2017 | 99 | 2017 |
| Temporal production of the signaling lipid phosphatidic acid by phospholipase D2 determines the output of extracellular signal-regulated kinase signaling in cancer cells F Zhang, Z Wang, M Lu, Y Yonekubo, X Liang, Y Zhang, P Wu, Y Zhou, ... Molecular and cellular biology 34 (1), 84-95, 2014 | 97 | 2014 |
| Inhibition of acid sphingomyelinase depletes cellular phosphatidylserine and mislocalizes K-Ras from the plasma membrane K Cho, D van der Hoeven, Y Zhou, M Maekawa, X Ma, W Chen, GD Fairn, ... Molecular and cellular biology 36 (2), 363-374, 2016 | 96 | 2016 |
| Bile acids modulate signaling by functional perturbation of plasma membrane domains Y Zhou, KN Maxwell, E Sezgin, M Lu, H Liang, JF Hancock, EJ Dial, ... Journal of Biological Chemistry 288 (50), 35660-35670, 2013 | 94 | 2013 |
| Effect of indomethacin on bile acid-phospholipid interactions: implication for small intestinal injury induced by nonsteroidal anti-inflammatory drugs Y Zhou, EJ Dial, R Doyen, LM Lichtenberger American Journal of Physiology-Gastrointestinal and Liver Physiology 298 (5 …, 2010 | 90 | 2010 |
| Effect of salicylate on the elasticity, bending stiffness, and strength of SOPC membranes Y Zhou, RM Raphael Biophysical journal 89 (3), 1789-1801, 2005 | 87 | 2005 |
| Distinct binding preferences between Ras and Raf family members and the impact on oncogenic Ras signaling EM Terrell, DE Durrant, DA Ritt, NE Sealover, E Sheffels, ... Molecular cell 76 (6), 872-884. e5, 2019 | 71 | 2019 |
| Discovery of high-affinity noncovalent allosteric KRAS inhibitors that disrupt effector binding MJ McCarthy, CV Pagba, P Prakash, AK Naji, D van der Hoeven, H Liang, ... ACS omega 4 (2), 2921-2930, 2019 | 66 | 2019 |
John F HancockUniversity of Texas Medial School at HoustonVerified email at uth.tmc.edu
