Follow
Young-Hwan Jung
Title
Cited by
Cited by
Year
Discovery of potent antiallodynic agents for neuropathic pain targeting P2X3 receptors
YH Jung, YO Kim, H Lin, JH Cho, JH Park, SD Lee, J Bae, KM Kang, ...
ACS Chemical Neuroscience 8 (7), 1465-1478, 2017
302017
Structure–Activity Relationships and Optimization of 3,5-Dichloropyridine Derivatives As Novel P2X7 Receptor Antagonists
WG Lee, SD Lee, JH Cho, Y Jung, J Kim, TT Hien, KW Kang, H Ko, ...
Journal of Medicinal Chemistry 55 (8), 3687-3698, 2012
272012
P2Y14 Receptor Antagonists Reverse Chronic Neuropathic Pain in a Mouse Model
F Mufti, YH Jung, LA Giancotti, J Yu, Z Chen, NB Phung, KA Jacobson, ...
ACS Medicinal Chemistry Letters 11 (6), 1281-1286, 2020
252020
Exploration of Alternative Scaffolds for P2Y14 Receptor Antagonists Containing a Biaryl Core
YH Jung, J Yu, Z Wen, V Salmaso, TP Karcz, NB Phung, Z Chen, S Duca, ...
Journal of medicinal chemistry 63 (17), 9563-9589, 2020
232020
Design and synthesis of potent and selective P2X3 receptor antagonists derived from PPADS as potential pain modulators
JH Cho, KY Jung, Y Jung, MH Kim, H Ko, CS Park, YC Kim
European Journal of Medicinal Chemistry 70, 811-830, 2013
232013
Adipocyte P2Y14 receptors play a key role in regulating whole-body glucose and lipid homeostasis
S Jain, SP Pydi, YH Jung, M Scortichini, EL Kesner, TP Karcz, DN Cook, ...
JCI insight 6 (10), 2021
182021
Structure–Activity Relationship of Heterocyclic P2Y14 Receptor Antagonists: Removal of the Zwitterionic Character with Piperidine Bioisosteres
YH Jung, V Salmaso, Z Wen, JM Bennett, NB Phung, DI Lieberman, ...
Journal of medicinal chemistry 64 (8), 5099-5122, 2021
132021
Isobolographic analysis of drug combinations with intrathecal BRL52537 (κ-opioid agonist), pregabalin (calcium channel modulator), AF 353 (P2X3 receptor antagonist), and …
YH Jung, YO Kim, JH Han, YC Kim, MH Yoon
Anesthesia & Analgesia 125 (2), 670-677, 2017
122017
Structure activity relationship of 3-nitro-2-(trifluoromethyl)-2H-chromene derivatives as P2Y6 receptor antagonists
YH Jung, S Jain, V Gopinatth, NB Phung, ZG Gao, KA Jacobson
Bioorganic & medicinal chemistry letters 41, 128008, 2021
112021
Biological Evaluation of 5′-(N-Ethylcarboxamido)adenosine Analogues as Grp94-Selective Inhibitors
DK Tosh, CM Brackett, YH Jung, ZG Gao, M Banerjee, BSJ Blagg, ...
ACS Medicinal Chemistry Letters 12 (3), 373-379, 2021
102021
Synthesis and pharmacological characterization of multiply substituted 2H-chromene derivatives as P2Y6 receptor antagonists
YH Jung, Q Shah, SA Lewicki, A Pramanik, V Gopinatth, J Pelletier, ...
Bioorganic & medicinal chemistry letters 75, 128981, 2022
62022
Bridged Piperidine Analogues of a High Affinity Naphthalene-Based P2Y14R Antagonist
Z Wen, V Salmaso, YH Jung, NB Phung, V Gopinatth, Q Shah, ...
Journal of medicinal chemistry 65 (4), 3434-3459, 2022
62022
Structure activity relationship of 2-arylalkynyl-adenine derivatives as human A 3 adenosine receptor antagonists
J Yu, P Mannes, YH Jung, A Ciancetta, A Bitant, DI Lieberman, ...
Medchemcomm 9 (11), 1920-1932, 2018
52018
Effects of purinergic receptor deletion or pharmacologic modulation on pulmonary inflammation in mice
GS Whitehead, TP Karcz, DK Tosh, YH Jung, Z Wen, RG Campbell, ...
ACS Pharmacology & Translational Science 5 (10), 973-984, 2022
42022
Heterocyclic P2Y14 receptor antagonists
KA Jacobson, J Yu, A Ciancetta, Z Wen, YH Jung
WO 157417, A1, 2019
32019
Alicyclic Ring Size Variation of 4-Phenyl-2-naphthoic Acid Derivatives as P2Y14 Receptor Antagonists
Z Wen, A Pramanik, SA Lewicki, YH Jung, ZG Gao, JCR Randle, C Cronin, ...
Journal of Medicinal Chemistry 66 (13), 9076-9094, 2023
12023
Novel 5-hydroxy pyridine-based compound for use as p2x1 and p2x3 receptor antagonist and pharmaceutical composition comprising same
YC Kim, YH Jung
US Patent App. 16/494,212, 2020
12020
Heterocyclic P2Y14 receptor antagonists
KA Jacobson, J Yu, A Ciancetta, Z Wen, YH Jung
US Patent 11,584,736, 2023
2023
5-hydroxy pyridine-based compound for use as P2X1 and P2X3 receptor antagonist and pharmaceutical composition comprising same
YC Kim, YH Jung
US Patent 11,319,289, 2022
2022
P2Y14 receptor inhibition reverses mechanical sensitivity in a mouse model of chronic neuropathic pain
F Mufti, YH Jung, LA Giancotti, J Yu, Z Chen, NB Phung, KA Jacobson, ...
The FASEB Journal 36, 2022
2022
The system can't perform the operation now. Try again later.
Articles 1–20