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| IDH1 mutation is sufficient to establish the glioma hypermethylator phenotype S Turcan, D Rohle, A Goenka, LA Walsh, F Fang, E Yilmaz, C Campos, ... Nature 483 (7390), 479-483, 2012 | 2220 | 2012 |
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| Molecular profiling reveals biologically discrete subsets and pathways of progression in diffuse glioma M Ceccarelli, FP Barthel, TM Malta, TS Sabedot, SR Salama, BA Murray, ... Cell 164 (3), 550-563, 2016 | 2164 | 2016 |
| PTEN/PI3K/Akt pathway regulates the side population phenotype and ABCG2 activity in glioma tumor stem-like cells AM Bleau, D Hambardzumyan, T Ozawa, EI Fomchenko, JT Huse, ... Cell stem cell 4 (3), 226-235, 2009 | 975 | 2009 |
| Targeting brain cancer: advances in the molecular pathology of malignant glioma and medulloblastoma JT Huse, EC Holland Nature reviews cancer 10 (5), 319-331, 2010 | 937 | 2010 |
| Serpins promote cancer cell survival and vascular co-option in brain metastasis M Valiente, AC Obenauf, X Jin, Q Chen, XHF Zhang, DJ Lee, JE Chaft, ... Cell 156 (5), 1002-1016, 2014 | 909 | 2014 |
| The PTEN-regulating microRNA miR-26a is amplified in high-grade glioma and facilitates gliomagenesis in vivo JT Huse, C Brennan, D Hambardzumyan, B Wee, J Pena, ... Genes & development 23 (11), 1327-1337, 2009 | 674 | 2009 |
| The tumor microenvironment underlies acquired resistance to CSF-1R inhibition in gliomas DF Quail, RL Bowman, L Akkari, ML Quick, AJ Schuhmacher, JT Huse, ... Science 352 (6288), aad3018, 2016 | 641 | 2016 |
| Intratumoral heterogeneity of receptor tyrosine kinases EGFR and PDGFRA amplification in glioblastoma defines subpopulations with distinct growth factor response NJ Szerlip, A Pedraza, D Chakravarty, M Azim, J McGuire, Y Fang, ... Proceedings of the National Academy of Sciences 109 (8), 3041-3046, 2012 | 638 | 2012 |
| Orally administered colony stimulating factor 1 receptor inhibitor PLX3397 in recurrent glioblastoma: an Ivy Foundation Early Phase Clinical Trials Consortium phase II study N Butowski, H Colman, JF De Groot, AM Omuro, L Nayak, PY Wen, ... Neuro-oncology 18 (4), 557-564, 2015 | 573 | 2015 |
| Maturation and endosomal targeting of β-site amyloid precursor protein-cleaving enzyme: the Alzheimer's disease β-secretase JT Huse, DS Pijak, GJ Leslie, VMY Lee, RW Doms Journal of Biological Chemistry 275 (43), 33729-33737, 2000 | 573 | 2000 |
| Osteopontin-CD44 signaling in the glioma perivascular niche enhances cancer stem cell phenotypes and promotes aggressive tumor growth A Pietras, AM Katz, EJ Ekström, B Wee, JJ Halliday, KL Pitter, JL Werbeck, ... Cell stem cell 14 (3), 357-369, 2014 | 562 | 2014 |
| The mutational landscape of adenoid cystic carcinoma AS Ho, K Kannan, DM Roy, LGT Morris, I Ganly, N Katabi, D Ramaswami, ... Nature genetics 45 (7), 791-798, 2013 | 500 | 2013 |
| Longitudinal molecular trajectories of diffuse glioma in adults FP Barthel, KC Johnson, FS Varn, AD Moskalik, G Tanner, E Kocakavuk, ... Nature 576 (7785), 112-120, 2019 | 488 | 2019 |
| Benefit From Procarbazine, Lomustine, and Vincristine in Oligodendroglial Tumors Is Associated With Mutation of IDH JG Cairncross, M Wang, RB Jenkins, EG Shaw, C Giannini, DG Brachman, ... Journal of clinical oncology 32 (8), 783-790, 2014 | 483 | 2014 |
| Most human non-GCIMP glioblastoma subtypes evolve from a common proneural-like precursor glioma T Ozawa, M Riester, YK Cheng, JT Huse, M Squatrito, K Helmy, N Charles, ... Cancer cell 26 (2), 288-300, 2014 | 444 | 2014 |
| Stereotactic radiosurgery for melanoma brain metastases in patients receiving ipilimumab: safety profile and efficacy of combined treatment AP Kiess, JD Wolchok, CA Barker, MA Postow, V Tabar, JT Huse, ... International Journal of Radiation Oncology* Biology* Physics 92 (2), 368-375, 2015 | 402 | 2015 |
| Mutational burden, immune checkpoint expression, and mismatch repair in glioma: implications for immune checkpoint immunotherapy TR Hodges, M Ott, J Xiu, Z Gatalica, J Swensen, S Zhou, JT Huse, ... Neuro-oncology 19 (8), 1047-1057, 2017 | 399 | 2017 |
| Ibrutinib unmasks critical role of Bruton tyrosine kinase in primary CNS lymphoma C Grommes, A Pastore, N Palaskas, SS Tang, C Campos, D Schartz, ... Cancer discovery 7 (9), 1018-1029, 2017 | 396 | 2017 |
